Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK2 | P25098 | 3/20 | 0.55 |
| ▸ | GRK3 | P35626 | 3/20 | 0.55 |
| ▸ | GRK5 | P34947 | 2/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | CTSV | O60911 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.52 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.52 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.52 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10832939 | 0.91 | FFAR1 (0.58) | GRK2GRK3GRK5FFAR1CTSV | |
| SCHEMBL8009616 | 0.88 | FFAR1 (0.58) | GRK2GRK3GRK5FFAR1CTSV | |
| SCHEMBL23916262 | 0.87 | HTT (0.52) | GRK2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL5955117 | 0.86 | ALDH1A1 (0.64) | ALDH1A1LTA4HLMNAMEN1KMT2A | |
| SCHEMBL5287947 | 0.84 | FFAR1 (0.62) | GRK2GRK3GRK5FFAR1CTSV | |
| SCHEMBL28302706 | 0.84 | PDK1 (0.57) | GRK2GRK3GRK5FFAR1CTSV | |
| SCHEMBL23283424 | 0.84 | LTA4H (0.61) | PDK1PDK2PDK3PDK4MAOB | |
| SCHEMBL5229166 | 0.82 | BCHE (0.62) | FFAR1MAOBALDH1A1LTA4HCYP2D6 | |
| SCHEMBL9164404 | 0.82 | PLA2G4B (0.49) | FFAR1CYP2D6NR1H4SMPD1 | |
| SCHEMBL31748463 | 0.81 | ALDH1A1 (0.47) | CTSVCTSLALDH1A1LTA4HLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210353683-A1 | ADDITIVE FOR MEDIUM FOR PROMOTING PRODUCTION OF PARACRINE FACTOR | NISSAN CHEMICAL CORPORATION (JP) | 2021-11-18 | — | — | US | disclosed |
| EP-3851519-A1 | ADDITIVE FOR MEDIUM FOR PROMOTING PRODUCTION OF PARACRINE FACTOR | Nissan Chemical Corporation (JP) | 2021-07-21 | — | — | EP | disclosed |
| CN-112805268-A | Medium supplement reagent for promoting production of paracrine factor | 日产化学株式会社 | 2021-05-14 | — | — | CN | disclosed |
| US-20200165194-A1 | ADDITIVE COMPOSITION FOR CULTURE MEDIUM, ADDITIVE COMPOUND FOR CULTURE MEDIUM, AND METHOD FOR CULTURE OF CELLS OR TISSUE USING SAME | NISSAN CHEMICAL CORPORATION (JP) | 2020-05-28 | — | — | US | disclosed |
| WO-2020067477-A1 | ADDITIVE FOR MEDIUM FOR PROMOTING PRODUCTION OF PARACRINE FACTOR | 日産化学株式会社 | 2020-04-02 | — | — | WO | disclosed |
| US-9181186-B2 | Aromatic ring compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-11-10 | — | — | US | disclosed |
| US-20150045378-A1 | AROMATIC RING COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-02-12 | — | — | US | disclosed |
| EP-2816032-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2014-12-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150045378-A1 | AROMATIC RING COMPOUND | GPR119, GPR27, GPR4 | GRK2 153/4885GRK3 269/4885GRK5 120/4885 |
| US-20210353683-A1 | ADDITIVE FOR MEDIUM FOR PROMOTING PRODUCTION OF PARACRINE FACTOR | HGF, HDGF, FGF2 | GRK2 3303/4885GRK3 4193/4885GRK5 3279/4885 |
| US-20200165194-A1 | ADDITIVE COMPOSITION FOR CULTURE MEDIUM, ADDITIVE COMPOUND FOR CULTURE MEDIUM, AND METHOD FOR CULTURE OF CELLS OR TISSUE USING SAME | NEFM, FGF2, FGF1 | GRK2 2359/4885GRK3 3109/4885GRK5 1689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.