SCHEMBL163247

SCHEMBL163247

O=C(O)c1ccccc1C12CC3CC(C1)CC(c1ccccc1C(=O)O)(C3)C2(c1ccccc1C(=O)O)c1ccccc1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.46
ALDH1A1 P00352 3/20 0.41
ALOX15 P16050 1/20 0.41
P2RX7 Q99572 8/20 0.39
HPGD P15428 2/20 0.38
MAPT P10636 1/20 0.38
TSHR P16473 1/20 0.38
ALOX12 P18054 1/20 0.38
HTT P42858 1/20 0.38
ATM Q13315 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
HSD17B10 Q99714 1/20 0.38
FAAH O00519 1/20 0.37
CNR2 P34972 1/20 0.37
EPHX1 P07099 1/20 0.36
EPHX2 P34913 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2747082 0.79 KDM4E (0.47) KDM4EALDH1A1ALOX15P2RX7HPGD
SCHEMBL5475249 0.78 KDM4E (0.53) KDM4EALDH1A1ALOX15P2RX7HPGD
SCHEMBL5872142 0.73 MEN1 (0.40) KDM4EALDH1A1ALOX15P2RX7HPGD
Phthalic Acid SCHEMBL28793332 0.72 ALDH1A1 (0.70) KDM4EALDH1A1ALOX15P2RX7HPGD
SCHEMBL15093129 0.70 ALDH1A1 (0.43) KDM4EALDH1A1ALOX15HPGDMAPT
SCHEMBL8740875 0.68 P2RX7 (0.49) KDM4EP2RX7MEN1KMT2A
SCHEMBL4309684 0.68 KDM4E (0.46) KDM4EALDH1A1ALOX15HPGDMAPT
SCHEMBL30293277 0.67 ALDH1A1 (0.54) KDM4EALDH1A1ALOX15HPGDMAPT
SCHEMBL5834020 0.67 KDM4E (0.51) KDM4EALDH1A1ALOX15P2RX7HPGD
SCHEMBL3031194 0.67 ALDH1A1 (0.43) KDM4EALDH1A1ALOX15HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2739169-B1 POROUS CATALYTIC MATRICES FOR ELIMINATION OF TOXICANTS FOUND IN TOBACCO COMBUSTION PRODUCTS MASSACHUSETTS INST TECHNOLOGY (US) 2019-06-12 EP claimed
US-20140311507-A1 Porous Catalytic Matrices for Elimination of Toxicants Found in Tobacco Combustion Products MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2014-10-23 US claimed
EP-2739169-A2 POROUS CATALYTIC MATRICES FOR ELIMINATION OF TOXICANTS FOUND IN TOBACCO COMBUSTION PRODUCTS Massachusetts Institute Of Technology (US) 2014-06-11 EP claimed
WO-2013019865-A2 POROUS CATALYTIC MATRICES FOR ELIMINATION OF TOXICANTS FOUND IN TOBACCO COMBUSTION PRODUCTS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2013-02-07 WO claimed
US-20250276300-A1 REDUCTION OF MONOMERIC ISOCYANATES BY POROUS MATERIAL BASF SE (DE) 2025-09-04 US disclosed
EP-4291588-B1 REDUCTION OF MONOMERIC ISOCYANATES BY POROUS MATERIAL BASF SE (DE) 2025-08-20 EP disclosed
US-20250251092-A1 PORTABLE IOT-ENABLED GAS STORAGE SYSTEM WITH INTEGRATED HIDDEN MODULE ATOMIS INC. (JP) 2025-08-07 US disclosed
US-12227526-B2 Metal-organic framework materials comprising a diimine scaffold and methods for production thereof ExxonMobil Technology and Engineering Company (US) 2025-02-18 US disclosed
EP-3947396-B1 METAL-ORGANIC FRAMEWORK MATERIALS COMPRISING A DIIMINE SCAFFOLD AND METHODS FOR PRODUCTION THEREOF EXXONMOBIL TECHNOLOGY & ENGINEERING COMPANY (US) 2024-12-11 EP disclosed
US-12097481-B2 Process for preparing metal organic frameworks having improved water stability MOF Technologies Limited (GB) 2024-09-24 US disclosed
US-20240197868-A1 IMMUNOGENIC COMPOSITION CONTAINING AN ANTIGEN AND AN ADJUVANT COMPRISING AL-MOFS UNIVERSITE DE VERSAILLES-SAINT-QUENTIN-EN-YVELINES (FR) 2024-06-20 US disclosed
EP-4313133-A2 IMMUNOGENIC COMPOSITION CONTAINING AN ANTIGEN AND AN ADJUVANT COMPRISING AL-MOFS UNIVERSITE DE VERSAILLES-SAINT QUENTIN EN YVELINES (FR) 2024-02-07 EP disclosed
EP-1689670-A1 METHOD FOR THE CONTROLLED STORAGE AND RELEASE OF GASES USING AN ELECTROCHEMICALLY PRODUCED CRYSTALLINE, POROUS, ORGANOMETALLIC SKELETON MATERIAL BASF AKTIENGESELLSCHAFT (DE) 2006-08-16 EP disclosed
EP-1687462-A1 METHOD FOR ELECTROCHEMICAL PRODUCTION OF A CRYSTALLINE POROUS METAL ORGANIC SKELETON MATERIAL BASF AKTIENGESELLSCHAFT (DE) 2006-08-09 EP disclosed
WO-2006072573-A2 ADSORPTIVE PRODUCTION OF XENON FROM KRYPTON/XENON GAS MIXTURES BASF AKTIENGESELLSCHAFT (DE) 2006-07-13 WO disclosed
EP-1674555-A1 Concentration of methane in methane containing gas mixtures by adsorption BASF AKTIENGESELLSCHAFT (DE) 2006-06-28 EP disclosed
WO-2005049484-A1 METHOD FOR THE CONTROLLED STORAGE AND RELEASE OF GASES USING AN ELECTROCHEMICALLY PRODUCED CRYSTALLINE, POROUS, ORGANOMETALLIC SKELETON MATERIAL BASF AKTIENGESELLSCHAFT (DE) 2005-06-02 WO disclosed
WO-2005049892-A1 METHOD FOR ELECTROCHEMICAL PRODUCTION OF A CRYSTALLINE POROUS METAL ORGANIC SKELETON MATERIAL BASF AKTIENGESELLSCHAFT (DE) 2005-06-02 WO disclosed
EP-1471997-A1 METHOD FOR STORING, ABSORBING AND EMITTING GASES USING NOVEL FRAMEWORK MATERIALS BASF AKTIENGESELLSCHAFT (DE) 2004-11-03 EP disclosed
WO-2003064030-A1 METHOD FOR STORING, ABSORBING AND EMITTING GASES USING NOVEL FRAMEWORK MATERIALS BASF AKTIENGESELLSCHAFT (DE) 2003-08-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12227526-B2 Metal-organic framework materials comprising a diimine scaffold and methods for production thereof PICALM, ILK, CAD KDM4E 3487/4885ALDH1A1 2699/4885ALOX15 4145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.