Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of D-Glutamate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 3/20 | 0.52 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.41 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| D-Glutamate SCHEMBL330960 | 1.00 | CA1 (0.52) | CA1FOLH1BBOX1GRM8GRM6 | |
| D-Glutamate SCHEMBL330961 | 1.00 | CA1 (0.52) | CA1FOLH1BBOX1GRM8GRM6 | |
| D-Glutamate SCHEMBL18880 | 1.00 | CA1 (0.52) | CA1FOLH1BBOX1GRM8GRM6 | |
| D-Glutamate SCHEMBL541429 | 1.00 | CA1 (0.52) | CA1FOLH1BBOX1GRM8GRM6 | |
| D-Glutamate SCHEMBL16053546 | 0.98 | CA1 (0.50) | CA1FOLH1BBOX1GRM8GRM6 | |
| D-Glutamate SCHEMBL8853445 | 0.98 | CA1 (0.50) | CA1FOLH1BBOX1GRM8GRM6 | |
| D-Glutamate SCHEMBL1518007 | 0.98 | CA1 (0.50) | CA1FOLH1BBOX1GRM8GRM6 | |
| D-Glutamate SCHEMBL317909 | 0.98 | CA1 (0.50) | CA1FOLH1BBOX1GRM8GRM6 | |
| D-Glutamate SCHEMBL1897914 | 0.98 | CA1 (0.50) | CA1FOLH1BBOX1GRM8GRM6 | |
| D-Glutamate SCHEMBL2853212 | 0.98 | CA1 (0.50) | CA1FOLH1BBOX1GRM8GRM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 140056 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305328-B1 | NON-GELATIN VACCINE PROTECTANT COMPOSITION AND LIVE ATTENUATED INFLUENZA VACCINE | CHANGCHUN BCHT BIOTECHNOLOGY CO (CN) | 2026-05-27 | — | — | EP | claimed |
| EP-4747394-A2 | BIOPOLYMER, AND SYSTEM AND METHOD FOR PRODUCING BIOPOLYMER | Flexsea Ltd (GB) | 2026-05-27 | — | — | EP | claimed |
| CN-122085601-A | Photosensitive glue solution, preparation method of photosensitive glue solution and photosensitive dry film | — | 2026-05-26 | — | — | CN | claimed |
| CN-122074617-A | Compound cereal high-fiber rice crust for fermenting and enriching GABA and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122081070-A | Microbial inoculum synergistic agent for efficiently degrading straw at low temperature and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122094649-A | Personal care compositions | — | 2026-05-26 | — | — | CN | claimed |
| CN-122074670-A | Compound ferment rich in ergothioneine and probiotics and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122081109-A | Composite microbial inoculant for straw decomposition and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-115537446-B | Application of rhodococcus aether in conversion of cholesterol to produce 4-androstenedione | TIANJIN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-121406556-B | Coli engineering bacterium for high yield of glutathione and application thereof | Guangdong Zhumei Biomedical Technology Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| US-3989856-A | 3-Furyl beta-oxoalkyl sulfides and methods for using same for altering, modifying or enhancing the organoleptic properties of foodstuffs | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1976-11-02 | — | — | US | claimed |
| US-3988204-A | Production of glucoamylase for conversion of grain mashes in the production of grain spirits | JOSEPH E. SEAGRAM & SONS, INC. (US) | 1976-10-26 | — | — | US | claimed |
| US-3985908-A | 3-Furyl sulfides and foodstuff flavor compositions comprising same | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1976-10-12 | — | — | US | claimed |
| US-3985907-A | Novel 3-furyl beta oxoalkyl sulfides, processes for producing same and methods for using same for altering the organoleptic properties of foodstuffs | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1976-10-12 | — | — | US | claimed |
| US-3982038-A | Methods for using 3-furyl β-chalocogenalkyl sulfides for altering the organoleptic properties of foodstuffs, and compositions of matter containing 3-furyl β-chalcogenalkyl sulfides | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1976-09-21 | — | — | US | claimed |
| US-3966972-A | Packaged coated food product capable of being cooked using electrodes | LECTROFOOD, INC. (US) | 1976-06-29 | — | — | US | claimed |
| US-3961093-A | ORGANOLEPTIC PROPERTIES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1976-06-01 | — | — | US | claimed |
| US-3961090-A | COOKING IN A VACUUM SEALED OVEN BAG | THE E. KAHN'S SONS COMPANY (US) | 1976-06-01 | — | — | US | claimed |
| US-3950555-A | Method of tenderizing and improving the flavor of food | STROMBERG BENGT | 1976-04-13 | — | — | US | claimed |
| US-3940501-A | BETA-PHENYL-PROPIONIC ACID | LEVER BROTHERS COMPANY (US) | 1976-02-24 | — | — | US | claimed |