Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KCNJ6 | P48051 | 13/20 | 0.41 |
| ▸ | KCNJ3 | P48549 | 13/20 | 0.41 |
| ▸ | KCNJ5 | P48544 | 11/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16347011 | 0.80 | ALDH1A1 (0.40) | ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL27329778 | 0.80 | GAA (0.46) | ALDH1A1 | |
| SCHEMBL31462462 | 0.78 | ALDH1A1 (0.49) | ALDH1A1KDM4EHSD17B10KCNJ6KCNJ3 | |
| SCHEMBL3364096 | 0.78 | ALDH1A1 (0.49) | ALDH1A1KDM4EHSD17B10KCNJ6KCNJ3 | |
| SCHEMBL22133076 | 0.76 | DRD2 (0.46) | ALDH1A1KCNJ6KCNJ3KCNJ5 | |
| SCHEMBL23748795 | 0.76 | KDM4E (0.46) | ALDH1A1KDM4EHSD17B10KCNJ6KCNJ3 | |
| SCHEMBL27847371 | 0.76 | HCAR3 (0.42) | ALDH1A1KDM4EHSD17B10KCNJ6KCNJ3 | |
| SCHEMBL1695102 | 0.75 | KDM4E (0.50) | ALDH1A1KDM4EHSD17B10KCNJ6KCNJ3 | |
| SCHEMBL6525498 | 0.75 | KDM4E (0.46) | ALDH1A1KDM4EHSD17B10KCNJ6KCNJ3 | |
| SCHEMBL855347 | 0.75 | KDM4E (0.46) | ALDH1A1KDM4EHSD17B10KCNJ6KCNJ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828379-B2 | Pyrrolo-pyrrole carbamate and related organic compounds, pharmaceutical compositions, and medical uses thereof | ABIDE THERAPEUTICS, INC. (US) | 2017-11-28 | — | — | US | disclosed |
| US-9828379-B2 | Pyrrolo-pyrrole carbamate and related organic compounds, pharmaceutical compositions, and medical uses thereof | ABIDE THERAPEUTICS, INC. (US) | 2017-11-28 | — | — | US | disclosed |
| US-9828379-B2 | Pyrrolo-pyrrole carbamate and related organic compounds, pharmaceutical compositions, and medical uses thereof | ABIDE THERAPEUTICS, INC. (US) | 2017-11-28 | — | — | US | disclosed |
| US-20160137649-A1 | PYRROLO-PYRROLE CARBAMATE AND RELATED ORGANIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF | ABIDE THERAPEUTICS, INC. | 2016-05-19 | — | — | US | disclosed |
| US-20160137649-A1 | PYRROLO-PYRROLE CARBAMATE AND RELATED ORGANIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF | ABIDE THERAPEUTICS, INC. | 2016-05-19 | — | — | US | disclosed |
| US-20160137649-A1 | PYRROLO-PYRROLE CARBAMATE AND RELATED ORGANIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF | ABIDE THERAPEUTICS, INC. | 2016-05-19 | — | — | US | disclosed |
| EP-3016653-A1 | PYRROLO-PYRROLE CARBAMATE AND RELATED ORGANIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF | Abide Therapeutics, Inc. (US) | 2016-05-11 | — | — | EP | disclosed |
| WO-2015003002-A1 | PYRROLO-PYRROLE CARBAMATE AND RELATED ORGANIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF | ABIDE THERAPEUTICS, INC. (US) | 2015-01-08 | — | — | WO | disclosed |
| WO-2015003002-A1 | PYRROLO-PYRROLE CARBAMATE AND RELATED ORGANIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF | ABIDE THERAPEUTICS, INC. (US) | 2015-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160137649-A1 | PYRROLO-PYRROLE CARBAMATE AND RELATED ORGANIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF | FAAH, FAAH2, ABHD6 | ALDH1A1 2203/4885KDM4E 1114/4885HSD17B10 1905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.