Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | APP | P05067 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | PTPRA | P18433 | 1/20 | 0.61 |
| ▸ | PTPRB | P23467 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.53 |
| ▸ | DUSP5 | Q16690 | 2/20 | 0.53 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29421649 | 1.00 | MAPK1 (0.73) | MAPK1ALDH1A1APPCYP1A2HIF1A | |
| SCHEMBL10621059 | 1.00 | MAPK1 (0.73) | MAPK1ALDH1A1APPCYP1A2HIF1A | |
| SCHEMBL93701 | 0.90 | APP (0.72) | MAPK1ALDH1A1APPCYP1A2HIF1A | |
| SCHEMBL93700 | 0.90 | APP (0.72) | MAPK1ALDH1A1APPCYP1A2HIF1A | |
| SCHEMBL29353967 | 0.90 | APP (0.72) | MAPK1ALDH1A1APPCYP1A2HIF1A | |
| SCHEMBL29912825 | 0.88 | APP (0.69) | MAPK1ALDH1A1APPCYP1A2HIF1A | |
| SCHEMBL10621065 | 0.84 | MAPK1 (1.00) | MAPK1ALDH1A1APPCYP1A2HIF1A | |
| SCHEMBL1098204 | 0.84 | MAPK1 (1.00) | MAPK1ALDH1A1APPCYP1A2HIF1A | |
| SCHEMBL1098207 | 0.84 | MAPK1 (1.00) | MAPK1ALDH1A1APPCYP1A2HIF1A | |
| SCHEMBL10621049 | 0.83 | MAPK1 (0.98) | MAPK1ALDH1A1APPCYP1A2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 267 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170315031-A1 | TISSUE AND CELL STAIN FORMULA WITH A NOVEL MOLECULE OBTAINED FROM PAPAVER RHOEAS | BUDAK MEHMET (TR) | 2017-11-02 | — | — | US | claimed |
| EP-3209292-A1 | TISSUE AND CELL STAIN FORMULA WITH A NOVEL MOLECULE OBTAINED FROM PAPAVER RHOEAS | Budak, Mehmet (TR) | 2017-08-30 | — | — | EP | claimed |
| CN-104744217-A | Hydroquinone synthesis method | JIANGSU YANGNONG CHEMICAL GROUP CO LTD | 2015-07-01 | — | — | CN | claimed |
| US-7481975-B2 | Hydrogen peroxide indicator and method | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2009-01-27 | — | — | US | claimed |
| US-20040265170-A1 | Hydrogen peroxide indicator and method | 3M INNOVATIVE PROPERTIES COMPANY | 2004-12-30 | — | — | US | claimed |
| US-6790411-B1 | MONITORING STERILIZATION OF SURGICAL AND MEDICAL EQUIPMENT BY COLORIMETRIC ANALYSIS USING DYES | 3M INNOVATIVE PROPERTIES COMPANY | 2004-09-14 | — | — | US | claimed |
| EP-1366196-A4 | METHODS AND COMPOSITIONS OF AMPLIFYING RNA | BAYLOR COLLEGE MEDICINE (US) | 2004-07-07 | — | — | EP | claimed |
| EP-1366196-A2 | METHODS AND COMPOSITIONS OF AMPLIFYING RNA | BAYLOR COLLEGE OF MEDICINE (US) | 2003-12-03 | — | — | EP | claimed |
| US-20030186237-A1 | Methods and compositions of amplifying RNA | BAYLOR COLLEGE OF MEDICINE | 2003-10-02 | — | — | US | claimed |
| US-6531581-B1 | When incorporated into hairpin oligonucleotides these quench the fluorescence of fluorophores linked to the 5'-terminus of the oligonucleotide | SEROLOGICALS, INC. | 2003-03-11 | — | — | US | claimed |
| EP-1236040-A1 | HYDROGEN PEROXIDE INDICATOR AND METHOD | 3M Innovative Properties Company (US) | 2002-09-04 | — | — | EP | claimed |
| WO-2002065093-A2 | METHODS AND COMPOSITIONS OF AMPLIFYING RNA | BAYLOR COLLEGE OF MEDICINE (US) | 2002-08-22 | — | — | WO | claimed |
| WO-2001040792-A1 | HYDROGEN PEROXIDE INDICATOR AND METHOD | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2001-06-07 | — | — | WO | claimed |
| EP-1086115-A2 | PURINES AND PYRIMIDINES LINKED TO A QUENCHER | Intergen Company (US) | 2001-03-28 | — | — | EP | claimed |
| US-6117986-A | QUENCHING FLUORESCENCE | INTERGEN COMPANY, L.P. (US) | 2000-09-12 | — | — | US | claimed |
| WO-1999064431-A2 | PURINES AND PYRIMIDINES LINKED TO A QUENCHER | INTERGEN COMPANY (US) | 1999-12-16 | — | — | WO | claimed |
| US-11975221-B2 | Anti-microbial multilayer fabric media and method for making same | Shuai Danmeng (US) | 2024-05-07 | — | — | US | disclosed |
| US-11953493-B2 | Biophotonic methods for increasing in situ energy production and energy emission in biological cells and tissues | FLE INTERNATIONAL S.R.L. (IT) | 2024-04-09 | — | — | US | disclosed |
| US-6117986-A | QUENCHING FLUORESCENCE | INTERGEN COMPANY, L.P. (US) | 2000-09-12 | — | — | US | disclosed |
| WO-1999064431-A2 | PURINES AND PYRIMIDINES LINKED TO A QUENCHER | INTERGEN COMPANY (US) | 1999-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170315031-A1 | TISSUE AND CELL STAIN FORMULA WITH A NOVEL MOLECULE OBTAINED FROM PAPAVER RHOEAS | MYADM, PRSS8, MKI67 | THRB 3702/4885MAPK1 255/4885ALDH1A1 450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.