Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | APP | P05067 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | PTPRA | P18433 | 1/20 | 0.61 |
| ▸ | PTPRB | P23467 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.53 |
| ▸ | DUSP5 | Q16690 | 2/20 | 0.53 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10621059 | 1.00 | MAPK1 (0.73) | MAPK1ALDH1A1APPCYP1A2HIF1A | |
| SCHEMBL1638375 | 1.00 | MAPK1 (0.73) | MAPK1ALDH1A1APPCYP1A2HIF1A | |
| SCHEMBL93701 | 0.90 | APP (0.72) | MAPK1ALDH1A1APPCYP1A2HIF1A | |
| SCHEMBL93700 | 0.90 | APP (0.72) | MAPK1ALDH1A1APPCYP1A2HIF1A | |
| SCHEMBL29353967 | 0.90 | APP (0.72) | MAPK1ALDH1A1APPCYP1A2HIF1A | |
| SCHEMBL29912825 | 0.88 | APP (0.69) | MAPK1ALDH1A1APPCYP1A2HIF1A | |
| SCHEMBL10621065 | 0.84 | MAPK1 (1.00) | MAPK1ALDH1A1APPCYP1A2HIF1A | |
| SCHEMBL1098204 | 0.84 | MAPK1 (1.00) | MAPK1ALDH1A1APPCYP1A2HIF1A | |
| SCHEMBL1098207 | 0.84 | MAPK1 (1.00) | MAPK1ALDH1A1APPCYP1A2HIF1A | |
| SCHEMBL10621049 | 0.83 | MAPK1 (0.98) | MAPK1ALDH1A1APPCYP1A2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 257 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112946140-B | Method for detecting water-soluble anion synthetic pigment in food | 广州市食品检验所（广州市酒类检测中心） | 2023-03-21 | — | — | CN | claimed |
| WO-2022188373-A1 | METHOD FOR DETECTING WATER-SOLUBLE ANIONIC SYNTHETIC PIGMENT IN FOOD | 广州市食品检验所（广州市酒类检测中心） | 2022-09-15 | — | — | WO | claimed |
| EP-4547208-B1 | PROCESS FOR REMOVING THE COLOUR FROM PREVIOUSLY DYED KERATINOUS HAIR FIBRES | OREAL (FR) | 2026-05-27 | — | — | EP | disclosed |
| US-12636246-B2 | Process for colouring hair keratin fibers, comprising the application of a composition comprising at least one (poly)carbodiimide compound and a composition comprising at least one associative polymer and a particular compound | L'OREAL (FR) | 2026-05-26 | — | — | US | disclosed |
| CN-122094656-A | Method for dyeing hair keratin fibres, comprising the step of washing the hair keratin fibres with a particular composition and subsequently applying to the hair keratin fibres a particular dyeing composition | — | 2026-05-26 | — | — | CN | disclosed |
| WO-2026039882-A1 | METHODS FOR REDUCING COLOR FADING IN COLOR-TREATED HAIR | L'OREAL (FR) | 2026-02-26 | — | — | WO | disclosed |
| US-20260043720-A1 | STABILIZED TWO-PART HEMATOXYLIN SOLUTION UTILIZING pH ADJUSTMENT | VENTANA MED SYST INC (US) | 2026-02-12 | — | — | US | disclosed |
| US-20260027027-A1 | FRAGRANCED COMPOSITION COMPRISING AT LEAST ONE SULFUR-COMPRISING ANTIOXIDANT COMPOUND, AT LEAST ONE ORGANIC UV SCREENING AGENT AND AT LEAST ONE FRAGRANCING SUBSTANCE | OREAL (FR) | 2026-01-29 | — | — | US | disclosed |
| US-12533303-B2 | Composition for the simultaneous bleaching and dyeing of keratin fibres and process using this composition | L'OREAL (FR) | 2026-01-27 | — | — | US | disclosed |
| US-20260007583-A1 | COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION | OREAL (FR) | 2026-01-08 | — | — | US | disclosed |
| US-20250381106-A1 | COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION | OREAL (FR) | 2025-12-18 | — | — | US | disclosed |
| US-20220178795-A1 | CYTOLOGICAL STAINING COMPOSITIONS AND USES THEREOF | TRIPATH IMAGING, INC. | 2022-06-09 | — | — | US | disclosed |
| US-11331257-B2 | Biophotonic compositions and methods for providing biophotonic treatment | KLOX TECHNOLOGIES INC. (CA) | 2022-05-17 | — | — | US | disclosed |
| US-11324823-B2 | Biophotonic materials and uses thereof | KLOX TECHNOLOGIES INC. (CA) | 2022-05-10 | — | — | US | disclosed |
| EP-3986366-A1 | COMPOSITION COMPRISING AT LEAST ONE ALKOXYSILANE, AT LEAST ONE NON-AMINO SILICONE AND WATER, THE ALKOXYSILANE/NON-AMINO SILICONE MASS RATIO RANGING FROM 95/5 TO 5/95 | L'OREAL (FR) | 2022-04-27 | — | — | EP | disclosed |
| CN-114340588-A | Composition comprising at least one alkoxysilane of formula (I), at least one alkoxysilane of formula (II), at least one non-amino silicone and optionally a pigment and/or direct dye | 莱雅公司 | 2022-04-12 | — | — | CN | disclosed |
| EP-3151861-B1 | SILICONE-BASED BIOPHOTONIC COMPOSITIONS AND USES THEREOF | KLOX TECH INC (CA) | 2022-04-06 | — | — | EP | disclosed |
| US-20220090993-A1 | STABILIZED TWO-PART HEMATOXYLIN SOLUTION UTILIZING pH ADJUSTMENT | VENTANA MEDICAL SYSTEMS, INC. | 2022-03-24 | — | — | US | disclosed |
| US-11274997-B2 | Cytological staining compositions and uses thereof | TRIPATH IMAGING, INC. (US) | 2022-03-15 | — | — | US | disclosed |
| CN-114184593-A | Dynamic surface enhanced Raman spectroscopy detection method | 厦门大学 | 2022-03-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12533303-B2 | Composition for the simultaneous bleaching and dyeing of keratin fibres and process using this composition | KRT18, CA12, CA7 | THRB 2468/4885MAPK1 2416/4885ALDH1A1 1626/4885 |
| US-20260027027-A1 | FRAGRANCED COMPOSITION COMPRISING AT LEAST ONE SULFUR-COMPRISING ANTIOXIDANT COMPOUND, AT LEAST ONE ORGANIC UV SCREENING AGENT AND AT LEAST ONE FRAGRANCING SUBSTANCE | CBR3, CBR1, ERCC1 | THRB 3716/4885MAPK1 2148/4885ALDH1A1 52/4885 |
| US-20250381106-A1 | COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION | KRT18, VIM, MAP1LC3A | THRB 4386/4885MAPK1 1975/4885ALDH1A1 730/4885 |
| US-20260007583-A1 | COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION | KRT18, F12, VIM | THRB 3644/4885MAPK1 1232/4885ALDH1A1 1427/4885 |
| US-20260043720-A1 | STABILIZED TWO-PART HEMATOXYLIN SOLUTION UTILIZING pH ADJUSTMENT | SMCHD1, KIT, CD68 | THRB 3803/4885MAPK1 892/4885ALDH1A1 1823/4885 |
| US-12636246-B2 | Process for colouring hair keratin fibers, comprising the application of a composition comprising at least one (poly)carbodiimide compound and a composition comprising at least one associative polymer and a particular compound | KRT18, CYC1, CYBA | THRB 1477/4885MAPK1 1320/4885ALDH1A1 197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.