Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CPA1 | P15085 | 2/20 | 0.31 |
| ▸ | CPB1 | P15086 | 1/20 | 0.31 |
| ▸ | CPA3 | P15088 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3787466 | 0.82 | ALDH1A1 (0.35) | TDP1KDM4EALDH1A1POLBAPOBEC3G | |
| SCHEMBL8893948 | 0.82 | KDM4E (0.32) | TDP1KDM4EALDH1A1POLBAPOBEC3G | |
| SCHEMBL8341038 | 0.82 | KDM4E (0.32) | TDP1KDM4EALDH1A1POLBAPOBEC3G | |
| SCHEMBL4122580 | 0.79 | APEX1 (0.35) | TDP1KDM4EALDH1A1POLBAPOBEC3G | |
| SCHEMBL1285166 | 0.74 | TBXAS1 (0.43) | ALDH1A1SLC22A6 | |
| SCHEMBL17250967 | 0.73 | GABBR2 (0.43) | — | |
| SCHEMBL11260715 | 0.70 | — | — | |
| SCHEMBL10231795 | 0.70 | GRM1 (0.34) | KDM4E | |
| SCHEMBL4112058 | 0.70 | POLB (0.35) | POLB | |
| SCHEMBL1696772 | 0.70 | HPGD (0.36) | TDP1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9061067-B2 | Polypeptide protracting tags | NOVO NORDISK A/S (DK) | 2015-06-23 | — | — | US | disclosed |
| US-20120088716-A1 | Polypeptide Protracting Tags | NOVO NORDISK A/S (DK) | 2012-04-12 | — | — | US | disclosed |
| US-20090111730-A1 | Polypeptide protracting tags | NOVO NORDISK A/S (DK) | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088716-A1 | Polypeptide Protracting Tags | VIP, FGB, NPPA | TDP1 1834/4885KDM4E 4692/4885ALDH1A1 4220/4885 |
| US-20090111730-A1 | Polypeptide protracting tags | LNPEP, FGB, ENPEP | TDP1 2852/4885KDM4E 4806/4885ALDH1A1 3105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.