Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25954061 | 0.93 | ELANE (0.46) | ACHEELANECA12CA1CA2 | |
| SCHEMBL164160 | 0.93 | ELANE (0.46) | ACHEELANECA12CA1CA2 | |
| SCHEMBL25954054 | 0.91 | RELA (0.62) | ACHERELANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25954108 | 0.87 | LTA4H (0.48) | NPC1RAB9AELANECA12CA1 | |
| SCHEMBL25954134 | 0.87 | ELANE (0.42) | ACHENPC1RAB9AELANECA12 | |
| SCHEMBL25954105 | 0.87 | ESR2 (0.48) | NPC1RAB9AELANECA12CA1 | |
| SCHEMBL25954058 | 0.87 | LTA4H (0.48) | NPC1RAB9AELANECA12CA1 | |
| SCHEMBL25954129 | 0.87 | TEAD4 (0.44) | ACHENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8782519 | 0.87 | TSHR (0.44) | ACHENPC1RAB9ACA1CA2 | |
| SCHEMBL1011203 | 0.86 | KIF11 (0.45) | ELANEKIF11SMN1; SMN2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023140186-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | 株式会社トクヤマ | 2023-07-27 | — | — | WO | disclosed |
| WO-2023136213-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | 株式会社トクヤマ | 2023-07-20 | — | — | WO | disclosed |
| US-9643905-B2 | Phenylnaphthol derivatives | TOKUYAMA CORPORATION (JP) | 2017-05-09 | — | — | US | disclosed |
| US-9487693-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2016-11-08 | — | — | US | disclosed |
| US-9487693-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2016-11-08 | — | — | US | disclosed |
| US-20160130203-A1 | NOVEL PHENYLNAPHTHOL DERIVATIVES | TOKUYAMA CORPORATION (JP) | 2016-05-12 | — | — | US | disclosed |
| US-20150034887-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2015-02-05 | — | — | US | disclosed |
| US-20150034887-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2015-02-05 | — | — | US | disclosed |
| US-8916071-B2 | Chromene compound and curable composition | TOKUYAMA CORPORATION (JP) | 2014-12-23 | — | — | US | disclosed |
| US-20140225050-A1 | CHROMENE COMPOUND AND CURABLE COMPOSITION | TOKUYAMA CORPORATION (JP) | 2014-08-14 | — | — | US | disclosed |
| US-20120121934-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2012-05-17 | — | — | US | disclosed |
| US-8147726-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2012-04-03 | — | — | US | disclosed |
| US-8147726-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2012-04-03 | — | — | US | disclosed |
| US-8123987-B2 | Chromene compounds | TOKUYAMA CORPORATION (JP) | 2012-02-28 | — | — | US | disclosed |
| US-8123987-B2 | Chromene compounds | TOKUYAMA CORPORATION (JP) | 2012-02-28 | — | — | US | disclosed |
| US-20110062396-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2011-03-17 | — | — | US | disclosed |
| US-20110062396-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2011-03-17 | — | — | US | disclosed |
| US-20100230648-A1 | Chromene Compounds | TOKUYAMA CORPORATION (JP) | 2010-09-16 | — | — | US | disclosed |
| US-20100230648-A1 | Chromene Compounds | TOKUYAMA CORPORATION (JP) | 2010-09-16 | — | — | US | disclosed |
| EP-1978022-A1 | CHROMENE COMPOUNDS | TOKUYAMA CORPORATION (JP) | 2008-10-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160130203-A1 | NOVEL PHENYLNAPHTHOL DERIVATIVES | AHR, ARL1, PAH | ACHE 3663/4885RELA 1546/4885NPC1 2951/4885 |
| US-20100230648-A1 | Chromene Compounds | H1-4, RB1, H1-0 | ACHE 2565/4885RELA 1644/4885NPC1 3522/4885 |
| US-20150034887-A1 | CHROMENE COMPOUND | CRY2, TRMT1, CDK20 | ACHE 1859/4885RELA 4102/4885NPC1 3167/4885 |
| US-20140225050-A1 | CHROMENE COMPOUND AND CURABLE COMPOSITION | CRY2, CRY1, CDYL | ACHE 2034/4885RELA 1916/4885NPC1 4022/4885 |
| US-20110062396-A1 | CHROMENE COMPOUND | CDYL, NR0B1, NR1H2 | ACHE 2579/4885RELA 2673/4885NPC1 809/4885 |
| US-20120121934-A1 | CHROMENE COMPOUND | TST, CNOT1, CNOT9 | ACHE 2105/4885RELA 4169/4885NPC1 1530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.