Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phenolsulfonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 5/20 | 0.54 |
| ▸ | CA12 known ✓ | O43570 | 3/20 | 0.54 |
| ▸ | CA1 known ✓ | P00915 | 3/20 | 0.54 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.45 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.54 |
| ▸ | DUSP5 | Q16690 | 3/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | DUSP6 | Q16828 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenolsulfonic Acid SCHEMBL30756570 | 0.97 | LMNA (0.59) | LMNACA2CA12CA9CA1 | |
| Phenolsulfonic Acid SCHEMBL125056 | 0.97 | LMNA (0.59) | LMNACA2CA12CA9CA1 | |
| Phenolsulfonic Acid SCHEMBL2518118 | 0.97 | LMNA (0.59) | LMNACA2CA12CA9CA1 | |
| Phenolsulfonic Acid SCHEMBL27472854 | 0.95 | LMNA (0.56) | LMNACA2CA12CA9CA1 | |
| Phenolsulfonic Acid SCHEMBL710820 | 0.95 | LMNA (0.56) | LMNACA2CA12CA9CA1 | |
| Phenolsulfonic Acid SCHEMBL11202643 | 0.95 | LMNA (0.56) | LMNACA2CA12CA9CA1 | |
| Phenolsulfonic Acid SCHEMBL11198896 | 0.95 | LMNA (0.56) | LMNACA2CA12CA9CA1 | |
| Phenolsulfonic Acid SCHEMBL7671608 | 0.95 | LMNA (0.56) | LMNACA2CA12CA9CA1 | |
| Phenolsulfonic Acid SCHEMBL10758562 | 0.95 | LMNA (0.56) | LMNACA2CA12CA9CA1 | |
| Phenolsulfonic Acid SCHEMBL8764688 | 0.95 | LMNA (0.56) | LMNACA2CA12CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3263145-B1 | ANTIMICROBIAL COMPOSITIONS AND METHODS FOR LOCKING CATHETERS | BECTON DICKINSON CO (US) | 2021-01-20 | — | — | EP | claimed |
| US-9872941-B2 | Antimicrobial compositions and methods for locking catheters | BECTON, DICKINSON AND COMPANY (US) | 2018-01-23 | — | — | US | claimed |
| EP-3263145-A1 | ANTIMICROBIAL COMPOSITIONS AND METHODS FOR LOCKING CATHETERS | Becton, Dickinson and Company (US) | 2018-01-03 | — | — | EP | claimed |
| EP-1998825-B1 | ANTIMICROBIAL COMPOSITIONS AND METHODS FOR LOCKING CATHETERS | BECTON DICKINSON CO (US) | 2017-10-18 | — | — | EP | claimed |
| US-20170216493-A1 | Antimicrobial Compositions and Methods for Locking Catheters | BECTON, DICKINSON AND COMPANY | 2017-08-03 | — | — | US | claimed |
| US-9649411-B2 | Antimicrobial compositions and methods for locking catheters | BECTON, DICKINSON AND COMPANY (US) | 2017-05-16 | — | — | US | claimed |
| US-20160213818-A1 | Antimicrobial Compositions and Methods for Locking Catheters | BECTON, DICKINSON AND COMPANY | 2016-07-28 | — | — | US | claimed |
| JP-2009528360-A | — | — | 2009-08-06 | — | — | JP | claimed |
| EP-1998825-A2 | ANTIMICROBIAL COMPOSITIONS AND METHODS FOR LOCKING CATHETERS | Becton, Dickinson and Company, Wagner, Jaconda (US) | 2008-12-10 | — | — | EP | claimed |
| WO-2007100776-A2 | ANTIMICROBIAL COMPOSITIONS AND METHODS FOR LOCKING CATHETERS | BECTON, DICKINSON AND COMPANY (US) | 2007-09-07 | — | — | WO | claimed |
| US-20070202177-A1 | Antimicrobial Compositions and Methods for Locking Catheters | BECTON, DICKINSON AND COMPANY (US) | 2007-08-30 | — | — | US | claimed |
| EP-1073470-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2001-02-07 | — | — | EP | claimed |
| WO-2000048636-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2000-08-24 | — | — | WO | claimed |
| EP-3263145-B1 | ANTIMICROBIAL COMPOSITIONS AND METHODS FOR LOCKING CATHETERS | BECTON DICKINSON CO (US) | 2021-01-20 | — | — | EP | disclosed |
| US-20200197310-A1 | Technology for Preparation of Macromolecular Microspheres | NEXBIO, INC. | 2020-06-25 | — | — | US | disclosed |
| US-10583086-B2 | Technology for preparation of macromolecular microspheres | ANSUN BIOPHARMA, INC. (US) | 2020-03-10 | — | — | US | disclosed |
| US-6221383-B1 | BLEND OF AT LEAST TWO POLYMERS, OR AT LEAST ONE POLYMER AND A SOLUBLE POLYVINYLPYRROLIDONE, IN COMBINATION WITH A DRUG PROVIDES A PRESSURE-SENSITIVE ADHESIVE COMPOSITION FOR A TRANSDERMAL DRUG DELIVERY SYSTEM | NOVEN PHARMACEUTICALS, INC. | 2001-04-24 | — | — | US | disclosed |
| US-6024976-A | TRANSDERMAL DRUG DELIVERY WITH PRESSURE SENSITIVE ADHESIVE COMPOSITION OF POLYVINYLPYRROLIDONE WITH DRUG IN MULTILAYER PATCH | NOVEN PHARMACEUTICALS, INC. (US) | 2000-02-15 | — | — | US | disclosed |
| US-5656286-A | BLEND OF TWO POLYMERS; PRESSURE SENSITIVE ADHESIVE | NOVEN PHARMACEUTICALS, INC. (US) | 1997-08-12 | — | — | US | disclosed |
| US-5120325-A | Color-matched sterile adhesive bandages containing melanin-like pigment composition | FLESHTONES PRODUCTS CO., INC. (US) | 1992-06-09 | — | — | US | disclosed |