Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 7/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728463 | 0.90 | CES1 (0.52) | CES1SRCPRSS1CTSGCTRB1 | |
| Hydrogen Peroxide SCHEMBL29060971 | 0.90 | CES1 (0.52) | CES1SRCPRSS1CTSGCTRB1 | |
| SCHEMBL28442493 | 0.84 | CES1 (0.47) | CES1SRCPRSS1CTSGCTRB1 | |
| SCHEMBL9321972 | 0.84 | PPARA (0.47) | CES1SRCPRSS1CTSGCTRB1 | |
| SCHEMBL759622 | 0.83 | CES1 (0.50) | CES1SRCPRSS1CTSGCTRB1 | |
| SCHEMBL12982174 | 0.82 | CA2 (0.47) | CES1ALDH1A1TDP1MEN1MAPT | |
| SCHEMBL4312735 | 0.82 | ALDH1A1 (0.47) | POLBALDH1A1TSHRTDP1MAPK1 | |
| SCHEMBL27835153 | 0.82 | SRC (0.46) | CES1SRCPRSS1CTSGCTRB1 | |
| SCHEMBL11762158 | 0.81 | CES1 (0.44) | CES1SRCPRSS1CTSGCTRB1 | |
| SCHEMBL26064181 | 0.81 | CES1 (0.49) | CES1SRCPRSS1CTSGCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9757493-B2 | Cement products and methods of making and using the same | PIONEER SURGICAL TECHNOLOGY, INC. (US) | 2017-09-12 | — | — | US | claimed |
| US-20160250376-A1 | CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME | TUTOGEN MEDICAL, INC. | 2016-09-01 | — | — | US | claimed |
| EP-2192886-A2 | CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME | Pioneer Surgical Technology, Inc. (US) | 2010-06-09 | — | — | EP | claimed |
| US-20090270527-A1 | CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME | ANGSTROM MEDICA (US) | 2009-10-29 | — | — | US | claimed |
| WO-2009029734-A2 | CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME | PIONEER SURGICAL TECHNOLOGY, INC. (US) | 2009-03-05 | — | — | WO | claimed |
| US-20250083136-A1 | METHODS AND SYSTEMS FOR MODIFYING SELECTIVITY IN CATALYTIC REACTIONS | U.S. DEPARTMENT OF ENERGY | 2025-03-13 | — | — | US | disclosed |
| CN-111253583-B | Dilatant hybrid dynamic polymer and dilatant realization method thereof | 厦门天策材料科技有限公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-108329265-B | Imidazole ion-containing photocuring monomer and application thereof in self-repairing photocuring material | 北京化工大学 | 2020-11-03 | — | — | CN | disclosed |
| US-10799610-B2 | Cement products and methods of making and using the same | PIONEER SURGICAL TECHNOLOGY, INC. (US) | 2020-10-13 | — | — | US | disclosed |
| CN-111253583-A | Dilatancy hybrid dynamic polymer and method for realizing dilatancy thereof | 翁秋梅 | 2020-06-09 | — | — | CN | disclosed |
| CN-111171329-A | Plastic dilatancy polymer and method for realizing dilatancy thereof | 翁秋梅 | 2020-05-19 | — | — | CN | disclosed |
| US-10413632-B2 | Cement products and methods of making and using the same | PIONEER SURGICAL TECHNOLOGY, INC. (US) | 2019-09-17 | — | — | US | disclosed |
| US-20070032568-A1 | Cement products and methods of making and using the same | ANGSTROM MEDICA (US) | 2007-02-08 | — | — | US | disclosed |
| US-6987136-B2 | Bioactive spinal implant material and method of manufacture thereof | VITA SPECIAL PURPOSE CORPORATION (US) | 2006-01-17 | — | — | US | disclosed |
| EP-1463465-A1 | BIOACTIVE SPINAL IMPLANTS AND METHOD OF MANUFACTURE THEREOF | Vita Special Purpose Corporation (US) | 2004-10-06 | — | — | EP | disclosed |
| EP-1408883-A1 | BIOACTIVE SPINAL IMPLANT MATERIAL AND METHOD OF MANUFACTURE THEREOF | Vita Licensing Inc. (US) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003053290-A1 | BIOACTIVE SPINAL IMPLANTS AND METHOD OF MANUFACTURE THEREOF | VITA SPECIAL PURPOSE CORPORATION (US) | 2003-07-03 | — | — | WO | disclosed |
| US-20030125739-A1 | Bioactive spinal implants and method of manufacture thereof | VITA SPECIAL PURPOSE CORP. | 2003-07-03 | — | — | US | disclosed |
| US-20030087984-A1 | Bioactive spinal implant material and method of manufacture thereof | VITA SPECIAL PURPOSE CORP. | 2003-05-08 | — | — | US | disclosed |
| WO-2003005937-A1 | BIOACTIVE SPINAL IMPLANT MATERIAL AND METHOD OF MANUFACTURE THEREOF | VITA LICENSING, INC. (US) | 2003-01-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250083136-A1 | METHODS AND SYSTEMS FOR MODIFYING SELECTIVITY IN CATALYTIC REACTIONS | HMBS, UNG, MPG | CES1 351/4885SRC 994/4885PRSS1 813/4885 |
| US-20070032568-A1 | Cement products and methods of making and using the same | BMP2, ETF1, EPHX2 | CES1 3566/4885SRC 1416/4885PRSS1 4633/4885 |
| US-20160250376-A1 | CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME | BHMT2, SHMT1, BHMT | CES1 4426/4885SRC 2079/4885PRSS1 4801/4885 |
| US-10799610-B2 | Cement products and methods of making and using the same | BHMT2, SHMT1, BHMT | CES1 4426/4885SRC 2079/4885PRSS1 4801/4885 |
| US-10413632-B2 | Cement products and methods of making and using the same | BHMT2, SHMT1, BHMT | CES1 4426/4885SRC 2079/4885PRSS1 4801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.