Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 1/20 | 0.72 |
| ▸ | ERN1 | O75460 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | CGAS | Q8N884 | 4/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.49 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.49 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.49 |
| ▸ | ABAT | P80404 | 1/20 | 0.49 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1320502 | 0.93 | PRKDC (0.72) | PRKDCERN1ALDH1A1TDP1KDM4E | |
| SCHEMBL7410524 | 0.85 | PRKDC (0.61) | PRKDCERN1ALDH1A1TDP1KDM4E | |
| SCHEMBL515642 | 0.84 | PRKDC (1.00) | PRKDCERN1ALDH1A1TDP1KDM4E | |
| SCHEMBL23094474 | 0.83 | XDH (0.54) | PRKDCERN1ALDH1A1TDP1LMNA | |
| SCHEMBL1002368 | 0.82 | ALDH1A1 (0.69) | PRKDCERN1ALDH1A1TDP1KDM4E | |
| SCHEMBL1004432 | 0.82 | ALDH1A1 (0.57) | PRKDCERN1ALDH1A1TDP1KDM4E | |
| SCHEMBL29459727 | 0.82 | ALDH1A1 (0.69) | PRKDCERN1ALDH1A1TDP1KDM4E | |
| SCHEMBL29459687 | 0.82 | ALDH1A1 (0.57) | PRKDCERN1ALDH1A1TDP1KDM4E | |
| SCHEMBL698744 | 0.82 | PRKDC (0.81) | PRKDCERN1ALDH1A1TDP1KDM4E | |
| SCHEMBL23094682 | 0.81 | LMNA (0.75) | PRKDCERN1ALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250179087-A1 | COMPOUNDS AND THEIR USES AS LPAR5 ANTAGONISTS | Immunophage Biotech (Shanghai) Co., Ltd. (CN) | 2025-06-05 | — | — | US | disclosed |
| CN-119403800-A | Compounds and their use as LPAR5 antagonists | 艾美斐生物医药科技(上海)有限公司 | 2025-02-07 | — | — | CN | disclosed |
| EP-4486742-A1 | COMPOUNDS AND THEIR USES AS LPAR5 ANTAGONISTS | IMMUNOPHAGE BIOTECH (SHANGHAI) CO., LTD. (CN) | 2025-01-08 | — | — | EP | disclosed |
| US-20240239787-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2024-07-18 | — | — | US | disclosed |
| US-20240239787-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2024-07-18 | — | — | US | disclosed |
| EP-4334294-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | Nanyang Technological University (SG) | 2024-03-13 | — | — | EP | disclosed |
| US-11767286-B2 | Phenylpropionate compound, preparation method for same, and applications thereof | SUZHOU PHARMAVAN CO., LTD (CN) | 2023-09-26 | — | — | US | disclosed |
| WO-2023165591-A1 | COMPOUNDS AND THEIR USES AS LPAR5 ANTAGONISTS | IMMUTHER PHARMATECH (SHANGHAI) CO., LTD. (CN) | 2023-09-07 | — | — | WO | disclosed |
| CN-116635371-A | Polycyclic pyridazinone derivative serving as SOS1 inhibitor, and preparation method and application thereof | 苏州阿尔脉生物科技有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-116606256-A | Benzimidazole-4-carboxamide derivatives with selective PARP-1 inhibition effect | 山东大学 | 2023-08-18 | — | — | CN | disclosed |
| US-7790896-B2 | RNA-selective probes for live cell imaging of nuclear structure and function | NEW YORK UNIVERSITY (US) | 2010-09-07 | — | — | US | disclosed |
| US-20100190831-A1 | GPR120 RECEPTOR AGONISTS AND USES THEREOF | METABOLEX, INC. | 2010-07-29 | — | — | US | disclosed |
| US-20100190831-A1 | GPR120 RECEPTOR AGONISTS AND USES THEREOF | METABOLEX, INC. | 2010-07-29 | — | — | US | disclosed |
| WO-2010080537-A1 | GPR120 RECEPTOR AGONISTS AND USES THEREOF | METABOLEX, INC. (US) | 2010-07-15 | — | — | WO | disclosed |
| US-20100048901-A1 | NOVEL CURCUMIN DERIVATIVE | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2010-02-25 | — | — | US | disclosed |
| EP-2123637-A1 | NOVEL CURCUMIN DERIVATIVE | Tokyo Institute of Technology (JP) | 2009-11-25 | — | — | EP | disclosed |
| US-20090111962-A1 | Palladium Complexes and Polymerization and Coupling Processes Thereof | WEST CHESTER UNIVERSITY OF PENNSYLVANIA OF THE STATE SYSTEM OF HIGHER EDUCATION | 2009-04-30 | — | — | US | disclosed |
| US-20080064037-A1 | RNA-SELECTIVE PROBES FOR LIVE CELL IMAGING OF NUCLEAR STRUCTURE AND FUNCTION | NEW YORK UNIVERSITY (US) | 2008-03-13 | — | — | US | disclosed |
| US-20080064037-A1 | RNA-SELECTIVE PROBES FOR LIVE CELL IMAGING OF NUCLEAR STRUCTURE AND FUNCTION | NEW YORK UNIVERSITY (US) | 2008-03-13 | — | — | US | disclosed |
| US-3976695-A | Halogen substituted α-(aminoalkyl)-3,4-dihydroxybenzyl alcohols | SMITHKLINE CORPORATION (US) | 1976-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048901-A1 | NOVEL CURCUMIN DERIVATIVE | BACE1, APP, BACE2 | PRKDC 4869/4885ERN1 2254/4885ALDH1A1 253/4885 |
| US-20080064037-A1 | RNA-SELECTIVE PROBES FOR LIVE CELL IMAGING OF NUCLEAR STRUCTURE AND FUNCTION | SNRPE, HNRNPUL2, EFTUD2 | PRKDC 2754/4885ERN1 157/4885ALDH1A1 4222/4885 |
| US-11767286-B2 | Phenylpropionate compound, preparation method for same, and applications thereof | PLAT, TFPI, PF4 | PRKDC 4436/4885ERN1 4206/4885ALDH1A1 711/4885 |
| US-20100190831-A1 | GPR120 RECEPTOR AGONISTS AND USES THEREOF | GPR119, GPR52, GCGR | PRKDC 4823/4885ERN1 3254/4885ALDH1A1 3347/4885 |
| US-20090111962-A1 | Palladium Complexes and Polymerization and Coupling Processes Thereof | DDT, PDCD2L, PDCD1LG2 | PRKDC 565/4885ERN1 4681/4885ALDH1A1 1671/4885 |
| US-20240239787-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | BRIX1, TP53, XPOT | PRKDC 2794/4885ERN1 1051/4885ALDH1A1 1975/4885 |
| US-20250179087-A1 | COMPOUNDS AND THEIR USES AS LPAR5 ANTAGONISTS | LPAR5, LPAR3, LPAR2 | PRKDC 4072/4885ERN1 3850/4885ALDH1A1 2592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.