Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29891064 | 1.00 | SIRT2 (0.40) | SIRT2SIRT1TDP1L3MBTL1ALOX12 | |
| SCHEMBL30618856 | 0.86 | BACE1 (0.43) | SIRT2SIRT1TDP1L3MBTL1ALOX12 | |
| SCHEMBL2354617 | 0.86 | BACE1 (0.43) | SIRT2SIRT1TDP1L3MBTL1ALOX12 | |
| SCHEMBL5670529 | 0.81 | DHFR (0.42) | TDP1L3MBTL1ALOX12DHFRESR1 | |
| SCHEMBL29357296 | 0.81 | SIRT2 (0.50) | SIRT2SIRT1TDP1ALDH1A1CYP2A6 | |
| SCHEMBL31610342 | 0.81 | SIRT2 (0.50) | SIRT2SIRT1TDP1ALDH1A1CYP2A6 | |
| SCHEMBL14912 | 0.81 | SIRT2 (0.50) | SIRT2SIRT1TDP1ALDH1A1CYP2A6 | |
| SCHEMBL6863260 | 0.81 | SIRT2 (0.50) | SIRT2SIRT1TDP1ALDH1A1CYP2A6 | |
| SCHEMBL6077039 | 0.80 | ALDH1A1 (0.56) | TDP1L3MBTL1ALDH1A1CYP2A6TSHR | |
| SCHEMBL29434197 | 0.80 | ALDH1A1 (0.48) | SIRT2SIRT1TDP1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260003210-A1 | DIFFRACTIVE CONTACT LENSES | ALCON INC (CH) | 2026-01-01 | — | — | US | claimed |
| US-12379611-B2 | Diffractive contact lenses | ALCON INC. (CH) | 2025-08-05 | — | — | US | claimed |
| EP-4356169-A1 | MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2024-04-24 | — | — | EP | claimed |
| US-20230004023-A1 | DIFFRACTIVE CONTACT LENSES | ALCON INC. (CH) | 2023-01-05 | — | — | US | claimed |
| WO-2022263994-A1 | MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2022-12-22 | — | — | WO | claimed |
| US-20260133439-A1 | CONTACT LENSES WITH COLOR FILTERING ZONE | ALCON INC. (CH) | 2026-05-14 | — | — | US | disclosed |
| US-20260118700-A1 | DIFFRACTIVE MULTIFOCAL CONTACT LENS | ALCON INC (CH) | 2026-04-30 | — | — | US | disclosed |
| US-20260104598-A1 | COMPOSITE CONTACT LENSES WITH ULTRATHIN OBJECTS | ALCON INC (CH) | 2026-04-16 | — | — | US | disclosed |
| EP-4719751-A1 | METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2026-04-08 | — | — | EP | disclosed |
| EP-4719750-A1 | EMBEDDED HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2026-04-08 | — | — | EP | disclosed |
| EP-4719753-A1 | METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2026-04-08 | — | — | EP | disclosed |
| US-20260003210-A1 | DIFFRACTIVE CONTACT LENSES | ALCON INC (CH) | 2026-01-01 | — | — | US | disclosed |
| WO-2024246822-A1 | METHOD FOR MAKING EMBEDDED SILICONE HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2024-12-05 | — | — | WO | disclosed |
| US-20240316886-A1 | METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2024-09-26 | — | — | US | disclosed |
| EP-4356169-A1 | MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2024-04-24 | — | — | EP | disclosed |
| EP-4314118-A1 | POLYSILOXANE VINYLIC CROSSLINKERS WITH HIGH REFRACTIVE INDEX | Alcon Inc. (CH) | 2024-02-07 | — | — | EP | disclosed |
| US-20230004023-A1 | DIFFRACTIVE CONTACT LENSES | ALCON INC. (CH) | 2023-01-05 | — | — | US | disclosed |
| WO-2022263994-A1 | MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2022-12-22 | — | — | WO | disclosed |
| US-20220306810-A1 | POLYSILOXANE VINYLIC CROSSLINKERS WITH HIGH REFRACTIVE INDEX | ALCON INC. (CH) | 2022-09-29 | — | — | US | disclosed |
| WO-2015023001-A1 | NOVEL ORGANOPOLYSILOXANE, SURFACE TREATMENT AGENT COMPRISING THE SAME, RESIN COMPOSITION COMPRISING THE SAME, AND GELATINOUS PRODUCT OR CURED PRODUCT THEREOF | DOW CORNING TORAY CO., LTD. (JP) | 2015-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260133439-A1 | CONTACT LENSES WITH COLOR FILTERING ZONE | MYO1G, STRA6, GJA1 | SIRT2 1956/4885SIRT1 1496/4885TDP1 3729/4885 |
| US-20260003210-A1 | DIFFRACTIVE CONTACT LENSES | LBR, CRYZ, CRYAA | SIRT2 2090/4885SIRT1 1660/4885TDP1 2489/4885 |
| US-20260104598-A1 | COMPOSITE CONTACT LENSES WITH ULTRATHIN OBJECTS | CRYZ, CRYAA, LIMA1 | SIRT2 3625/4885SIRT1 3545/4885TDP1 3619/4885 |
| US-20260118700-A1 | DIFFRACTIVE MULTIFOCAL CONTACT LENS | DSG1, SDC1, DSP | SIRT2 1736/4885SIRT1 1224/4885TDP1 3016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.