SCHEMBL1661019

SCHEMBL1661019

CCCCNc1nc2c(N)ncnc2n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HSPA8 P11142 6/20 0.74
HSPA5 P11021 2/20 0.74
RXFP1 Q9HBX9 1/20 0.74
FBP1 P09467 1/20 0.73
SLC28A2 O43868 7/20 0.69
SLC29A1 Q99808 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1661023 1.00 HSPA8 (0.74) HSPA8HSPA5RXFP1FBP1SLC28A2
SCHEMBL14380122 1.00 HSPA8 (0.74) HSPA8HSPA5RXFP1FBP1SLC28A2
SCHEMBL11574082 0.97 HSPA8 (0.73) HSPA8HSPA5RXFP1FBP1SLC28A2
SCHEMBL11574099 0.97 HSPA8 (0.73) HSPA8HSPA5RXFP1FBP1SLC28A2
SCHEMBL6758944 0.96 HSPA8 (0.72) HSPA8HSPA5RXFP1FBP1SLC28A2
SCHEMBL6758942 0.96 HSPA8 (0.72) HSPA8HSPA5RXFP1FBP1SLC28A2
SCHEMBL6762435 0.90 FBP1 (0.79) HSPA8HSPA5RXFP1FBP1SLC28A2
SCHEMBL13127208 0.90 HSPA8 (0.80) HSPA8HSPA5RXFP1FBP1SLC28A2
SCHEMBL6762443 0.90 FBP1 (0.79) HSPA8HSPA5RXFP1FBP1SLC28A2
SCHEMBL6763143 0.90 HSPA8 (0.80) HSPA8HSPA5RXFP1FBP1SLC28A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250171740-A1 METHODS FOR GENERATING FUNCTIONAL HEMATOPOIETIC STEM CELLS THE BRIGHAM AND WOMEN'S HOSPITAL, INC. 2025-05-29 US claimed
US-11767523-B2 Acrylamide copolymerization for sequestration and production of single-stranded nucleic acid DANA-FARBER CANCER INSTITUTE, INC. (US) 2023-09-26 US claimed
EP-3383182-B1 METHODS FOR GENERATING FUNCTIONAL HEMATOPOIETIC STEM CELLS BRIGHAM & WOMENS HOSPITAL INC (US) 2023-06-07 EP claimed
US-20110262442-A1 COMPOSITIONS FOR TREATING CNS DISORDERS ADENIOS, INC. (US) 2011-10-27 US claimed
CN-122091465-A Plasma electrospray fusion ionization source and mass spectrum combined system and detection method 2026-05-26 CN disclosed
US-12623215-B2 Method for preparing a monolithic support on which uranyl cations are immobilised, and associated methods for capture and recovery COMMISSARIAT À L'ENERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES (FR) 2026-05-12 US disclosed
US-20260126354-A1 TISSUE TRANSFER HYDROGEL DEVICES SINGULAR GENOMICS SYSTEMS INC (US) 2026-05-07 US disclosed
US-12590053-B2 Process for preparing vanillin (meth)acrylates EVONIK OPERATIONS GMBH (DE) 2026-03-31 US disclosed
EP-3986610-B1 METHOD FOR PREPARING A MONOLITHIC SUPPORT ON WHICH URANYL CATIONS ARE IMMOBILISED, AND ASSOCIATED METHODS FOR CAPTURE AND RECOVERY COMMISSARIAT ENERGIE ATOMIQUE (FR) 2026-03-04 EP disclosed
EP-4211106-B1 A PROCESS FOR PREPARING VANILLIN (METH)ACRYLATES EVONIK OPERATIONS GMBH (DE) 2025-11-19 EP disclosed
EP-3791863-B1 PROCESS FOR THE PRODUCTION OF HYBRIDOSOMES ANJARIUM BIOSCIENCES AG (CH) 2025-09-10 EP disclosed
US-20250171740-A1 METHODS FOR GENERATING FUNCTIONAL HEMATOPOIETIC STEM CELLS THE BRIGHAM AND WOMEN'S HOSPITAL, INC. 2025-05-29 US disclosed
WO-2015013653-A1 GENERATING DEFINITIVE ENDODERM AND PANCREATIC PROGENITOR CELLS THE J. DAVID GLADSTONE INSTITUTES, A TESTAMENTARY TRUST ESTABLISHED UNDER THE WILL OF J. DAVID GLADSTONE (US) 2015-01-29 WO disclosed
US-20120277199-A1 Modulation of Gel Temperature of Poloxamer-Containing Formulations OTONOMY, INC. (US) 2012-11-01 US disclosed
EP-2490722-A2 MODULATION OF GEL TEMPERATURE OF POLOXAMER-CONTAINING FORMULATIONS Otonomy, Inc. (US) 2012-08-29 EP disclosed
WO-2011050206-A2 COMPOSITIONS AND METHODS FOR THE TREATMENT OF SINONASAL DISORDERS OTONOMY, INC. (US) 2011-04-28 WO disclosed
WO-2011049960-A2 COMPOSITIONS AND METHODS FOR THE TREATMENT OF SINONASAL DISORDERS OTONOMY, INC. (US) 2011-04-28 WO disclosed
WO-2011049958-A2 MODULATION OF GEL TEMPERATURE OF POLOXAMER-CONTAINING FORMULATIONS OTONOMY, INC. (US) 2011-04-28 WO disclosed
US-20090306225-A1 AURIS FORMULATIONS FOR TREATING OTIC DISEASES AND CONDITIONS OTONOMY, INC. (US) 2009-12-10 US disclosed
US-20070265223-A1 COMPOSITIONS AND METHODS OF ENHANCING SURVIVABILITY AND REDUCING INJURY OF CELLS, TISSUES, ORGANS, AND ORGANISMS UNDER HYPOXIC OR ISCHEMIC CONDITIONS IKARIA, INC. (US) 2007-11-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070265223-A1 COMPOSITIONS AND METHODS OF ENHANCING SURVIVABILITY AND REDUCING INJURY OF CELLS, TISSUES, ORGANS, AND ORGANISMS UNDER HYPOXIC OR ISCHEMIC CONDITIONS ADORA2A, ADORA2B, ADORA1 HSPA8 1006/4885HSPA5 1875/4885RXFP1 265/4885
US-12623215-B2 Method for preparing a monolithic support on which uranyl cations are immobilised, and associated methods for capture and recovery ORAI1, STIM1, STIM2 HSPA8 1245/4885HSPA5 1269/4885RXFP1 3952/4885
US-20090306225-A1 AURIS FORMULATIONS FOR TREATING OTIC DISEASES AND CONDITIONS OTC, AQP4, SLC26A4 HSPA8 1036/4885HSPA5 3165/4885RXFP1 294/4885
US-20260126354-A1 TISSUE TRANSFER HYDROGEL DEVICES CD68, ACTB, GJA1 HSPA8 218/4885HSPA5 201/4885RXFP1 1142/4885
US-12590053-B2 Process for preparing vanillin (meth)acrylates ADH1A, HVCN1, ADH1C HSPA8 2139/4885HSPA5 2439/4885RXFP1 4840/4885
US-20120277199-A1 Modulation of Gel Temperature of Poloxamer-Containing Formulations PTGIR, HSPH1, HSP90AA1 HSPA8 15/4885HSPA5 446/4885RXFP1 2585/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.