Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16626650 | 0.88 | SLC6A4 (0.33) | SLC6A2SLC6A3SLC6A4HTR2CNAMPT | |
| SCHEMBL16626624 | 0.85 | KLKB1 (0.33) | KDM4ENAMPT | |
| SCHEMBL19984028 | 0.83 | ALDH1A1 (0.37) | KDM4ENAMPTALDH1A1DGAT2 | |
| SCHEMBL16626750 | 0.83 | RAB9A (0.36) | HTR2CKDM4ENAMPTALDH1A1 | |
| SCHEMBL16626644 | 0.79 | CYP11B1 (0.37) | NAMPTDGAT2 | |
| SCHEMBL16626693 | 0.79 | TBXAS1 (0.31) | TBXAS1NAMPTALDH1A1 | |
| SCHEMBL19983950 | 0.79 | CYP11B1 (0.41) | SLC6A4DGAT2 | |
| SCHEMBL16626424 | 0.79 | MAPK14 (0.36) | KDM4ETBXAS1NAMPTALDH1A1 | |
| SCHEMBL19983960 | 0.78 | CYP11B1 (0.36) | NAMPTDGAT2 | |
| SCHEMBL17971579 | 0.78 | SLC6A2 (0.38) | P2RX7SLC6A2SLC6A3SLC6A4TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050412-A1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2015-04-09 | — | — | WO | disclosed |