Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16626624 | 0.89 | KLKB1 (0.33) | KDM4ENAMPT | |
| SCHEMBL16626650 | 0.88 | SLC6A4 (0.33) | CYP11B1CYP11B2NAMPT | |
| SCHEMBL19983960 | 0.85 | CYP11B1 (0.36) | CYP11B1CYP11B2CYP2C9NAMPTDGAT2 | |
| SCHEMBL19983950 | 0.83 | CYP11B1 (0.41) | CYP11B1CYP11B2CYP2C9DGAT2 | |
| SCHEMBL16626783 | 0.83 | P2RX7 (0.35) | ALDH1A1KDM4ENAMPTDGAT2 | |
| SCHEMBL16626644 | 0.83 | CYP11B1 (0.37) | CYP11B1CYP11B2NAMPTDGAT2PDE10A | |
| SCHEMBL16626750 | 0.81 | RAB9A (0.36) | ALDH1A1KDM4ENAMPTSMN1; SMN2 | |
| SCHEMBL19984031 | 0.80 | ALDH1A1 (0.38) | ALDH1A1KDM4EPOLBMAPTCYP11B1 | |
| SCHEMBL16626785 | 0.78 | HTR6 (0.44) | ALDH1A1KDM4EPOLBMAPTCYP11B1 | |
| Hydrochloric Acid SCHEMBL16618742 | 0.78 | HTR6 (0.43) | ALDH1A1KDM4EPOLBMAPTCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |