Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | MAT2A | P31153 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 3/20 | 0.34 |
| ▸ | BCR | P11274 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16626644 | 0.91 | CYP11B1 (0.37) | CYP11B1CYP11B2MAT2AABL1BCR | |
| SCHEMBL19983960 | 0.90 | CYP11B1 (0.36) | CYP11B1CYP11B2MAT2AABL1CYP3A4 | |
| SCHEMBL16626750 | 0.86 | RAB9A (0.36) | RAB9A | |
| SCHEMBL19984028 | 0.83 | ALDH1A1 (0.37) | CYP11B1CYP11B2CYP2C9DGAT2 | |
| SCHEMBL16626624 | 0.80 | KLKB1 (0.33) | RAB9A | |
| SCHEMBL16626783 | 0.79 | P2RX7 (0.35) | DGAT2SLC6A4 | |
| SCHEMBL16626650 | 0.79 | SLC6A4 (0.33) | CYP11B1CYP11B2MAT2ASLC6A4 | |
| SCHEMBL16626784 | 0.78 | HTR6 (0.42) | CYP11B1CYP11B2MAT2ADGAT2TRPM8 | |
| Hydrochloric Acid SCHEMBL16618786 | 0.77 | HTR6 (0.42) | CYP11B1CYP11B2MAT2ADGAT2TRPM8 | |
| SCHEMBL16626672 | 0.77 | ALDH1A1 (0.35) | NPC1RAB9ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |