Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | MAT2A | P31153 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | ABL1 | P00519 | 2/20 | 0.31 |
| ▸ | BCR | P11274 | 1/20 | 0.30 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.30 |
| ▸ | NAMPT | P43490 | 2/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.30 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.30 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983950 | 0.91 | CYP11B1 (0.41) | CYP11B1CYP11B2MAT2AROCK2DGAT2 | |
| SCHEMBL19983960 | 0.91 | CYP11B1 (0.36) | CYP11B1CYP11B2MAT2AROCK2DGAT2 | |
| SCHEMBL19984028 | 0.83 | ALDH1A1 (0.37) | CYP11B1CYP11B2DGAT2PDE10ANAMPT | |
| SCHEMBL16626624 | 0.82 | KLKB1 (0.33) | NAMPT | |
| SCHEMBL16626750 | 0.81 | RAB9A (0.36) | NAMPT | |
| SCHEMBL16626650 | 0.79 | SLC6A4 (0.33) | CYP11B1CYP11B2MAT2ANAMPT | |
| SCHEMBL16626783 | 0.79 | P2RX7 (0.35) | DGAT2NAMPT | |
| SCHEMBL17975821 | 0.79 | HTR6 (0.38) | CYP11B1CYP11B2MAT2AROCK2CHRM5 | |
| Hydrochloric Acid SCHEMBL16618980 | 0.79 | HTR6 (0.37) | CYP11B1CYP11B2MAT2AROCK2CHRM5 | |
| SCHEMBL16626086 | 0.73 | GRIN2B (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050412-A1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2015-04-09 | — | — | WO | disclosed |