Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | DGAT2 | Q96PD7 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.33 |
| ▸ | USP2 | O75604 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16626644 | 0.91 | CYP11B1 (0.37) | CYP11B1CYP11B2DGAT2MAT2AABL1 | |
| SCHEMBL19983950 | 0.90 | CYP11B1 (0.41) | CYP11B1CYP11B2DGAT2CYP3A4CYP2C19 | |
| SCHEMBL19984028 | 0.85 | ALDH1A1 (0.37) | CYP11B1CYP11B2DGAT2CYP2C9NAMPT | |
| SCHEMBL16626649 | 0.80 | HTR6 (0.38) | CYP11B1CYP11B2DGAT2LMNAMAT2A | |
| Hydrochloric Acid SCHEMBL16619246 | 0.79 | HTR6 (0.37) | CYP11B1CYP11B2DGAT2LMNAMAT2A | |
| SCHEMBL16626624 | 0.79 | KLKB1 (0.33) | NAMPT | |
| SCHEMBL16626650 | 0.78 | SLC6A4 (0.33) | CYP11B1CYP11B2MAT2ANAMPT | |
| SCHEMBL16626783 | 0.78 | P2RX7 (0.35) | DGAT2NAMPT | |
| SCHEMBL16626750 | 0.78 | RAB9A (0.36) | CLK4LMNANAMPT | |
| SCHEMBL16626590 | 0.74 | L3MBTL1 (0.33) | CYP1A2CYP3A4CYP2D6CLK4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |