Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16626650 | 0.90 | SLC6A4 (0.33) | NAMPT | |
| SCHEMBL16626750 | 0.89 | RAB9A (0.36) | KDM4ENAMPTRAB9A | |
| SCHEMBL19984028 | 0.89 | ALDH1A1 (0.37) | KDM4ENAMPT | |
| SCHEMBL16626783 | 0.85 | P2RX7 (0.35) | KDM4ENAMPT | |
| SCHEMBL16626644 | 0.82 | CYP11B1 (0.37) | NAMPT | |
| SCHEMBL19983950 | 0.80 | CYP11B1 (0.41) | RAB9A | |
| SCHEMBL19984136 | 0.79 | MEN1 (0.39) | NAMPT | |
| SCHEMBL19984004 | 0.79 | MEN1 (0.32) | KDM4ENAMPT | |
| SCHEMBL19983960 | 0.79 | CYP11B1 (0.36) | NAMPT | |
| SCHEMBL16626433 | 0.79 | EGFR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050412-A1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2015-04-09 | — | — | WO | disclosed |