Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Formaldehyde. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50845 | 0.87 | — | — | |
| SCHEMBL9562190 | 0.87 | — | — | |
| SCHEMBL9562194 | 0.87 | — | — | |
| SCHEMBL4329607 | 0.87 | — | — | |
| SCHEMBL1236243 | 0.72 | — | — | |
| SCHEMBL8239798 | 0.70 | ALDH1A1 (0.32) | — | |
| SCHEMBL13376965 | 0.69 | ALOX15 (0.35) | — | |
| SCHEMBL1591922 | 0.69 | ALOX15 (0.33) | — | |
| SCHEMBL14535056 | 0.66 | ALDH1A1 (0.34) | — | |
| SCHEMBL8934677 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9593193-B2 | Nitrile rubbers having low emission values | ARLANXEO DEUTSCHLAND GMBH (US) | 2017-03-14 | — | — | US | disclosed |
| US-20160108162-A1 | NITRILE RUBBERS HAVING LOW EMISSION VALUES | ARLANXEO DEUTSCHLAND GMBH (DE) | 2016-04-21 | — | — | US | disclosed |
| US-9279028-B2 | Nitrile rubbers having low emission values | LANXESS DEUTSCHLAND GMBH (DE) | 2016-03-08 | — | — | US | disclosed |
| US-20150105515-A1 | NITRILE RUBBERS HAVING LOW EMISSION VALUES | ARLANXEO DEUTSCHLAND GMBH (DE) | 2015-04-16 | — | — | US | disclosed |