SCHEMBL1666405

SCHEMBL1666405

CCCO[SiH](CCCN)Cc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.38
KIF11 P52732 2/20 0.34
HTR2A P28223 2/20 0.33
CYP2A6 P11509 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
LOXL2 Q9Y4K0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1001797 0.83 LTA4H (0.33)
SCHEMBL3481806 0.83 TP53 (0.41) SMN1; SMN2
SCHEMBL15302051 0.76 LTA4H (0.44) SMN1; SMN2
SCHEMBL29415969 0.75 KDM4E (0.35)
SCHEMBL29415920 0.74 CA2 (0.34)
SCHEMBL3481959 0.74 IDO1 (0.42)
SCHEMBL29415760 0.74 SMN1; SMN2 (0.40) SMN1; SMN2
SCHEMBL703150 0.72 TP53 (0.41) SMN1; SMN2
SCHEMBL705824 0.70 SIGMAR1 (0.43)
SCHEMBL5180297 0.70 SIGMAR1 (0.40) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2771379-A2 POLYMER, COMPOSITIONS AND PROCESS FOR PREPARING THEM DSM IP Assets B.V. (NL) 2014-09-03 EP claimed
US-20140242399-A1 POLYMER, COMPOSITIONS AND PROCESS FOR PREPARING THEM DSM IP ASSETS B.V. (NL) 2014-08-28 US claimed
WO-2013060767-A2 POLYMER, COMPOSITIONS AND PROCESS FOR PREPARING THEM DSM IP ASSETS B.V. (NL) 2013-05-02 WO claimed
US-12594700-B2 Coatings from polyisocyanurate coatings (rim) and their use in injection molding processes COVESTRO DEUTSCHLAND AG (DE) 2026-04-07 US disclosed
EP-4606829-A1 PROCESS FOR THE PREPARATION OF ALKOXYSILANE-FUNCTIONAL POLYURETHANES AND POLYURETHANE UREAS Covestro Deutschland AG (DE) 2025-08-27 EP disclosed
US-12331214-B2 Resistant 2K-PUR coatings COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2025-06-17 US disclosed
EP-3994192-B1 RESISTANT 2K-PUR COATINGS COVESTRO DEUTSCHLAND AG (DE) 2025-04-30 EP disclosed
US-20250043146-A1 MULTILAYER CONSTRUCTION ON METAL SUBSTRATES BASED ON POLYASPARTATE COATINGS COVESTRO DEUTSCHLAND AG (DE) 2025-02-06 US disclosed
EP-4453107-A1 MULTILAYER CONSTRUCTION ON METAL SUBSTRATES BASED ON POLYASPARATE COATINGS Covestro Deutschland AG (DE) 2024-10-30 EP disclosed
US-20240294798-A1 Coating Agents and Coatings That Are Obtainable Therefrom and Have Improved Resistance to Soiling and (Self-) Cleaning Properties COVESTRO DEUTSCHLAND AG (DE) 2024-09-05 US disclosed
EP-4359459-A1 COATING AGENTS AND COATINGS THAT ARE OBTAINABLE THEREFROM AND HAVE IMPROVED RESISTANCE TO SOILING AND (SELF-)CLEANING PROPERTIES Covestro Deutschland AG (DE) 2024-05-01 EP disclosed
EP-2305691-A1 Highly functional polyisocyanates containing allophanate and silane groups Bayer MaterialScience AG (DE) 2011-04-06 EP disclosed
WO-2010112157-A1 PROTECTIVE PAINT BAYER MATERIALSCIENCE AG (DE) 2010-10-07 WO disclosed
US-20090018302-A1 POLYISOCYANATES CONTAINING ALLOPHANATE AND SILANE GROUPS BAYER MATERIALSCIENCE AG (DE) 2009-01-15 US disclosed
EP-2014692-A2 Polyisocyanates containing allophanate and silane groups Bayer MaterialScience AG (DE) 2009-01-14 EP disclosed
US-20020016486-A1 PROCESS FOR PREPARING CARBAMATOORGANOSILANES AND ISOCYANATOORGANOSILANES DEGUSSA AG (DE) 2002-02-07 US disclosed
EP-1010704-A2 Process for preparing carbamato-organosilanes and isocyanato-organosilanes Degussa-Hüls Aktiengesellschaft (DE) 2000-06-21 EP disclosed
EP-0583581-B1 Process for making a silylisocyanurate OSI SPECIALTIES INC (US) 1997-05-28 EP disclosed
EP-0583581-A1 Process for making a silylisocyanurate OSi Specialties, Inc. (US) 1994-02-23 EP disclosed
US-5218133-A Process for making a silylisocyanurate UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12594700-B2 Coatings from polyisocyanurate coatings (rim) and their use in injection molding processes TST, C9, ESD MAOA 959/4885KIF11 4439/4885HTR2A 1799/4885
US-20020016486-A1 PROCESS FOR PREPARING CARBAMATOORGANOSILANES AND ISOCYANATOORGANOSILANES DDT, STOM, CPS1 MAOA 1081/4885KIF11 3334/4885HTR2A 3626/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.