Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1666405 | 0.83 | MAOA (0.38) | — | |
| SCHEMBL3481806 | 0.82 | TP53 (0.41) | LTA4HTP53ALDH1A1CYP3A4TSHR | |
| SCHEMBL15302051 | 0.75 | LTA4H (0.44) | LTA4HTP53ALDH1A1CYP3A4TSHR | |
| SCHEMBL29415969 | 0.74 | KDM4E (0.35) | LTA4HTP53ALDH1A1MAPK1 | |
| SCHEMBL29415920 | 0.73 | CA2 (0.34) | LTA4HTP53ALDH1A1TSHR | |
| SCHEMBL3481959 | 0.73 | IDO1 (0.42) | L3MBTL1 | |
| SCHEMBL29415760 | 0.73 | SMN1; SMN2 (0.40) | TP53ALDH1A1TSHR | |
| SCHEMBL5180297 | 0.72 | SIGMAR1 (0.40) | LTA4HTP53MAPK1 | |
| SCHEMBL11353289 | 0.71 | CALM1 (0.33) | TP53ALDH1A1TSHR | |
| SCHEMBL703150 | 0.71 | TP53 (0.41) | LTA4HTP53ALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2785726-B1 | ESTER-FUNCTIONAL SILANES AND THE PREPARATION AND USE THEREOF; AND USE OF IMINIUM COMPOUNDS AS PHASE TRANSFER CATALYSTS | DOW SILICONES CORP (US) | 2018-08-01 | — | — | EP | claimed |
| US-7863398-B2 | Process for making hydrolyzable silylated polymers | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2011-01-04 | — | — | US | claimed |
| EP-2134767-B1 | PROCESS FOR MAKING HYDROLYZABLE SILYLATED POLYMERS | MOMENTIVE PERFORMANCE MAT INC (US) | 2010-09-15 | — | — | EP | claimed |
| US-20080242825-A1 | Process for making hydrolyzable silylated polymers | MOMENTIVE PERFORMANCE MATERIALS INC. | 2008-10-02 | — | — | US | claimed |
| EP-2785726-B1 | ESTER-FUNCTIONAL SILANES AND THE PREPARATION AND USE THEREOF; AND USE OF IMINIUM COMPOUNDS AS PHASE TRANSFER CATALYSTS | DOW SILICONES CORP (US) | 2018-08-01 | — | — | EP | disclosed |
| EP-2573092-B1 | Method for the preparation and use of bis (alkoxysilylorgano)-dicarboxylates | DOW CORNING (US) | 2017-03-29 | — | — | EP | disclosed |
| US-9518072-B2 | Ester-functional silanes and the preparation and use thereof; and use of iminium compounds as phase transfer catalysts | DOW CORNING CORPORATION (US) | 2016-12-13 | — | — | US | disclosed |
| EP-2137198-B1 | EPOXYSILANES, PROCESSES FOR THEIR MANUFACTURE AND CURABLE COMPOSITIONS CONTAINING SAME | MOMENTIVE PERFORMANCE MAT INC (US) | 2016-05-18 | — | — | EP | disclosed |
| US-20150126676-A1 | Ester-Functional Silanes And The Preparation And Use Thereof; And Use Of Iminium Compounds As Phase Transfer Catalysts | DOW SILICONES CORPORATION | 2015-05-07 | — | — | US | disclosed |
| EP-2785726-A2 | ESTER-FUNCTIONAL SILANES AND THE PREPARATION AND USE THEREOF; AND USE OF IMINIUM COMPOUNDS AS PHASE TRANSFER CATALYSTS | Dow Corning Corporation (US) | 2014-10-08 | — | — | EP | disclosed |
| US-8580886-B2 | Method for the preparation and use of bis (alkoxysilylorgano)-dicarboxylates | DOW CORNING CORPORATION (US) | 2013-11-12 | — | — | US | disclosed |
| WO-2013081820-A2 | ESTER-FUNCTIONAL SILANES AND THE PREPARATION AND USE THEREOF;AND USE OF IMINIUM COMPOUNDS AS PHASE TRANSFER CATALYSTS | DOW CORNING CORPORATION (US) | 2013-06-06 | — | — | WO | disclosed |
| EP-2573092-A1 | Method for the preparation and use of bis (alkoxysilylorgano)-dicarboxylates | Dow Corning Corporation (US) | 2013-03-27 | — | — | EP | disclosed |
| US-20130072625-A1 | Method for the Preparation and Use of Bis (Alkoxysilylorgano)-Dicarboxylates | DOW CORNING CORPORATION (US) | 2013-03-21 | — | — | US | disclosed |
| US-7989651-B2 | trimethoxysilylpropyl-carbamic acid oxiranylmethyl ester; reacting glycidol with gamma-isocyanatopropyltriethoxysilane in presence of dibutyltin laurate catalyst | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2011-08-02 | — | — | US | disclosed |
| EP-2137198-A1 | EPOXYSILANES, PROCESSES FOR THEIR MANUFACTURE AND CURABLE COMPOSITIONS CONTAINING SAME | Momentive Performance Materials Inc. (US) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008112150-A1 | EPOXYSILANES, PROCESSES FOR THEIR MANUFACTURE AND CURABLE COMPOSITIONS CONTAINING SAME | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2008-09-18 | — | — | WO | disclosed |
| US-20080221238-A1 | Epoxysilanes, processes for their manufacture and curable compositions containing same | MOMENTIVE PERFORMANCE MATERIALS INC. | 2008-09-11 | — | — | US | disclosed |
| US-5905150-A | HEATING IN PRESENCE OF PHASE TRANSFER AGENT | GENERAL ELECTRIC COMPANY (US) | 1999-05-18 | — | — | US | disclosed |
| EP-0900801-A1 | Process for preparing organosilanes | GENERAL ELECTRIC COMPANY (US) | 1999-03-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072625-A1 | Method for the Preparation and Use of Bis (Alkoxysilylorgano)-Dicarboxylates | PBRM1, IPMK, BOLA2; BOLA2B | LTA4H 3770/4885TP53 2702/4885ALDH1A1 3400/4885 |
| US-20150126676-A1 | Ester-Functional Silanes And The Preparation And Use Thereof; And Use Of Iminium Compounds As Phase Transfer Catalysts | ICMT, INTS9, HDHD5 | LTA4H 2683/4885TP53 2712/4885ALDH1A1 2430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.