Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | GRM5 | P41594 | 2/20 | 0.44 |
| ▸ | SPR | P35270 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16735578 | 0.85 | POLB (0.56) | POLBALDH1A1HPGDRXFP1DPP4 | |
| SCHEMBL16735670 | 0.79 | MAPT (0.55) | POLBALDH1A1HPGDRXFP1L3MBTL1 | |
| SCHEMBL2143839 | 0.78 | ALDH1A1 (0.51) | ALDH1A1GRM5SPRHPGDL3MBTL1 | |
| SCHEMBL16735667 | 0.78 | POLB (0.51) | POLBALDH1A1HPGDRXFP1HSD17B10 | |
| SCHEMBL16735658 | 0.77 | POLB (0.53) | POLBALDH1A1HSP90AA1HSD17B10KDM4E | |
| SCHEMBL16735619 | 0.76 | POLB (0.52) | POLBHPGDRXFP1HSP90AA1L3MBTL1 | |
| SCHEMBL16735647 | 0.76 | POLB (0.49) | POLBALDH1A1SPRRXFP1HSP90AA1 | |
| SCHEMBL16735636 | 0.76 | HSP90AA1 (0.62) | POLBHSP90AA1 | |
| SCHEMBL16735634 | 0.76 | KDM4C (0.54) | POLBSPRRXFP1MAPTSMN1; SMN2 | |
| SCHEMBL16735639 | 0.75 | RXFP1 (0.46) | POLBRXFP1DPP4DPP8HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519505-B1 | TERTIARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES AND USES THEREOF | POLICHEM SA (LU) | 2015-05-27 | — | — | EP | claimed |