SCHEMBL167417

SCHEMBL167417

CC1(C)OB(c2cnc3ccccc3c2)OC1(C)C

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALPL P05186 1/20 0.57
LPL P06858 5/20 0.49
LIPG Q9Y5X9 5/20 0.49
CYP1A2 P05177 1/20 0.47
PDGFRB P09619 4/20 0.42
KDR P35968 2/20 0.42
ALDH1A1 P00352 1/20 0.41
CYP2A6 P11509 1/20 0.41
DGAT1 O75907 1/20 0.40
PDGFRA P16234 2/20 0.39
MGAM O43451 1/20 0.39
HTR3A P46098 1/20 0.38
IRAK4 Q9NWZ3 1/20 0.38
LMNA P02545 1/20 0.37
POLB P06746 1/20 0.37
TSHR P16473 1/20 0.37
RAB9A P51151 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1825954 0.84 LPL (0.65) ALPLLPLLIPGPDGFRBCYP2A6
SCHEMBL29831910 0.84 LPL (0.50) ALPLLPLLIPGCYP1A2PDGFRB
SCHEMBL29847497 0.84 LPL (0.50) ALPLLPLLIPGCYP1A2PDGFRB
SCHEMBL19106677 0.84 LPL (0.50) ALPLLPLLIPGCYP1A2PDGFRB
SCHEMBL12731574 0.83 DGAT1 (0.53) ALPLLPLLIPGCYP1A2PDGFRB
SCHEMBL27349470 0.83 LIPG (0.56) ALPLLPLLIPGPDGFRBKDR
SCHEMBL19106599 0.82 LPL (0.58) ALPLLPLLIPGPDGFRBALDH1A1
SCHEMBL14926830 0.81 ALPL (0.42) ALPLLPLLIPGCYP1A2PDGFRB
SCHEMBL14983523 0.81 CYP1A2 (0.50) ALPLCYP1A2PDGFRBALDH1A1CYP2A6
SCHEMBL23487533 0.81 LPL (0.47) ALPLLPLLIPGCYP1A2PDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118084934-A Fluorescent probe for detecting NADH, preparation method and biological application thereof 天津理工大学 2024-05-28 CN claimed
CN-113957441-B Etching solution and preparation method and application thereof 光华科学技术研究院(广东)有限公司 2024-01-02 CN claimed
CN-113957441-A Etching solution and preparation method and application thereof 光华科学技术研究院(广东)有限公司 2022-01-21 CN claimed
US-20250136556-A1 NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF ALLIANTHERA BOSTON INC. 2025-05-01 US disclosed
CN-117105936-B Imidazo [1,2-a ] pyridine compound serving as FLT3 inhibitor, and preparation method and application thereof 遵义医科大学 2025-01-24 CN disclosed
US-20240368104-A1 Novel Dialkoxynaphtho[2,3-C]Furan-1(3H)-One Derivatives and Pharmaceutical Composition For Preventing or Treating Respiratory Disease or SARS-COV-2 Infection Disease, Comprising Same DONG WHA PHARM. CO., LTD. (KR) 2024-11-07 US disclosed
EP-4430028-A2 NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF Allianthera (Suzhou) Biopharmaceutical Co., Ltd. (CN) 2024-09-18 EP disclosed
CN-118084778-A Preparation method of 3-hydroxyquinoline 甘肃汇健药业有限公司 2024-05-28 CN disclosed
CN-118084934-A Fluorescent probe for detecting NADH, preparation method and biological application thereof 天津理工大学 2024-05-28 CN disclosed
US-20240116914-A1 COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAID COMPOUND HODOGAYA CHEMICAL CO., LTD. (JP) 2024-04-11 US disclosed
WO-2024020170-A1 ARYL HYDROCARBON RECEPTOR AGONIST PRODRUGS AND METHODS OF USE THEREOF ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) 2024-01-25 WO disclosed
WO-2009042607-A1 THIAZOLOPYRIMIDINE P13K INHIBITOR COMPOUNDS AND METHODS OF USE GENENTECH, INC. (US) 2009-04-02 WO disclosed
EP-2041139-A2 PHARMACEUTICAL COMPOUNDS F.HOFFMANN-LA ROCHE AG (CH) 2009-04-01 EP disclosed
EP-1926729-A1 BENZOTHIAZOLE CYCLOBUTYL AMINE DERIVATIVES AND THEIR USE AS HISTAMINE-3 RECEPTORS LIGANDS ABBOTT LABORATORIES (US) 2008-06-04 EP disclosed
US-20080076758-A1 1S,4S)-2-((2-(1H-indazol-4-yl)-4- morpholinothieno[3,2-d]pyrirnidin-6- yl)methyl)-5-methylsulfonyl-2,5- diaza-bicyclo[2.2.1]heptane; 2-(6-fluoropyridin-3-yl)-6-((4- methylsulfonylpiperazin-1-yl)methyl)-4- morpholinothieno[3,2-d]pyrimidine; treats cancer mediated by pik3 kinase; enzyme inhibitors PIRAMED LIMITED (GB) 2008-03-27 US disclosed
WO-2007127175-A2 PHARMACEUTICAL COMPOUNDS F. HOFFMANN-LA ROCHE AG (CH) 2007-11-08 WO disclosed
WO-2007038074-A1 BENZOTHIAZOLE CYCLOBUTYL AMINE DERIVATIVES AND THEIR USE AS HISTAMINE-3 RECEPTORS LIGANDS ABBOTT LABORATORIES (US) 2007-04-05 WO disclosed
US-20070066588-A1 Benzothiazole cyclobutyl amine derivatives ABBVIE INC. 2007-03-22 US disclosed
US-20050148775-A1 Process for production of heteroaryl-type boron compounds with iridium catalyst MITSUBISHI RAYON CO., LTD. (JP) 2005-07-07 US disclosed
EP-1481978-A1 PROCESS FOR PRODUCTION OF HETEROARYL-TYPE BORON COMPOUNDS WITH IRIDIUM CATALYST Mitsubishi Rayon Co., Ltd. (JP) 2004-12-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250136556-A1 NOVEL MODULATORS OF THE ARYL HYDROCARBON RECEPTOR AND METHODS OF USE THEREOF AHR, ARNT, NR1H2 ALPL 2931/4885LPL 832/4885LIPG 1921/4885
US-20240368104-A1 Novel Dialkoxynaphtho[2,3-C]Furan-1(3H)-One Derivatives and Pharmaceutical Composition For Preventing or Treating Respiratory Disease or SARS-COV-2 Infection Disease, Comprising Same IL5, ACE2, IL15 ALPL 3584/4885LPL 3407/4885LIPG 3149/4885
US-20050148775-A1 Process for production of heteroaryl-type boron compounds with iridium catalyst PIN4, IPO5, HLCS ALPL 198/4885LPL 2994/4885LIPG 4113/4885
US-20080076758-A1 1S,4S)-2-((2-(1H-indazol-4-yl)-4- morpholinothieno[3,2-d]pyrirnidin-6- yl)methyl)-5-methylsulfonyl-2,5- diaza-bicyclo[2.2.1]heptane; 2-(6-fluoropyridin-3-yl)-6-((4- methylsulfonylpiperazin-1-yl)methyl)-4- morpholinothieno[3,2-d]pyrimidine; treats cancer mediated by pik3 kinase; enzyme inhibitors PIK3CA, PIK3CD, PIK3CB ALPL 3082/4885LPL 3598/4885LIPG 2592/4885
US-20070066588-A1 Benzothiazole cyclobutyl amine derivatives HRH2, HRH4, HRH1 ALPL 4765/4885LPL 3549/4885LIPG 2740/4885
US-20240116914-A1 COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAID COMPOUND LEF1, ELP1, EEF1A1 ALPL 1594/4885LPL 991/4885LIPG 950/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.