Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20143332 | 0.78 | KDM4E (0.55) | KDM4EALDH1A1HPGDHSD17B10P2RX3 | |
| SCHEMBL20118855 | 0.74 | KDM4E (0.34) | KDM4EALDH1A1HPGDHSD17B10P2RX3 | |
| SCHEMBL16769243 | 0.74 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10P2RX3 | |
| SCHEMBL19413644 | 0.72 | GABRA1 (0.34) | KDM4EALDH1A1HPGDHSD17B10P2RX3 | |
| SCHEMBL14015230 | 0.71 | KDM4E (0.71) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL14752379 | 0.68 | KDM4E (0.71) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL17229270 | 0.67 | KDM5A (0.32) | KDM5A | |
| SCHEMBL12433035 | 0.67 | NOS3 (0.36) | P2RX3P2RX2GABRA1GABRB2 | |
| SCHEMBL13167669 | 0.67 | LMNA (0.43) | KDM4EALDH1A1HPGDHSD17B10P2RX3 | |
| SCHEMBL23054799 | 0.66 | MAPT (0.35) | KDM4EALDH1A1HPGDHSD17B10P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787906-B2 | Biodegradable drug-polymer conjugate | POLYACTIVA PTY LTD (AU) | 2023-10-17 | — | — | US | disclosed |
| US-20220401455-A1 | BIODEGRADABLE DRUG-POLYMER CONJUGATE | POLYACTIVA PTY LTD (AU) | 2022-12-22 | — | — | US | disclosed |
| US-20180214561-A1 | EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2018-08-02 | — | — | US | disclosed |
| US-9968684-B2 | Polymer-NSAID conjugate | POLYACTIVA PTY LTD (AU) | 2018-05-15 | — | — | US | disclosed |
| US-9968684-B2 | Polymer-NSAID conjugate | POLYACTIVA PTY LTD (AU) | 2018-05-15 | — | — | US | disclosed |
| US-20170312363-A1 | MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2017-11-02 | — | — | US | disclosed |
| US-20170216308-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | POLYACTIVA PTY LTD (AU) | 2017-08-03 | — | — | US | disclosed |
| US-20170182173-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | POLYACTIVA PTY LTD (AU) | 2017-06-29 | — | — | US | disclosed |
| US-9572892-B2 | Polymer conjugate for delivery of a bioactive agent | POLYACTIVA PTY LTD (AU) | 2017-02-21 | — | — | US | disclosed |
| US-20160000929-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | POLYACTIVA PTY LTD (AU) | 2016-01-07 | — | — | US | disclosed |
| US-20150150999-A1 | POLYMER-NSAID CONJUGATE | POLYACTIVA PTY LTD (AU) | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150150999-A1 | POLYMER-NSAID CONJUGATE | PTGS1, PTGES3, PTGES | KDM4E 3166/4885ALDH1A1 216/4885HPGD 36/4885 |
| US-20180214561-A1 | EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF | MRPL38, CXCL8, ALG8 | KDM4E 2604/4885ALDH1A1 1061/4885HPGD 3535/4885 |
| US-20220401455-A1 | BIODEGRADABLE DRUG-POLYMER CONJUGATE | PTGER1, PTGDR, F12 | KDM4E 2195/4885ALDH1A1 688/4885HPGD 422/4885 |
| US-20160000929-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | PTGIS, PTGIR, PGF | KDM4E 4458/4885ALDH1A1 1399/4885HPGD 55/4885 |
| US-20170216308-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | PTGIS, PTGIR, PGF | KDM4E 4260/4885ALDH1A1 1738/4885HPGD 77/4885 |
| US-20170182173-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | PTGIS, PTGIR, PGF | KDM4E 3979/4885ALDH1A1 1479/4885HPGD 40/4885 |
| US-11787906-B2 | Biodegradable drug-polymer conjugate | ADRB3, PTGER3, CHRM3 | KDM4E 1912/4885ALDH1A1 907/4885HPGD 911/4885 |
| US-20170312363-A1 | MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR | HDGF, F11, F12 | KDM4E 4115/4885ALDH1A1 1582/4885HPGD 549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.