Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 5/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16795410 | 0.83 | L3MBTL3 (0.42) | KDM4EGAABRD4ALDH1A1 | |
| SCHEMBL16795329 | 0.79 | ALDH1A1 (0.43) | KDM4EHIF1AALDH1A1 | |
| SCHEMBL16795221 | 0.76 | HRH3 (0.40) | HIF1AACHEBACE1BCHE | |
| SCHEMBL16795137 | 0.75 | ACHE (0.34) | ACHEBACE1ALDH1A1BCHE | |
| SCHEMBL16795444 | 0.75 | GRIN2B (0.38) | KDM4EGAABRD4TDP1 | |
| SCHEMBL16795141 | 0.74 | CXCR3 (0.51) | CXCR3SIGMAR1ACHEBACE1BCHE | |
| SCHEMBL16795407 | 0.67 | KDM4E (0.44) | KDM4EALDH1A1 | |
| SCHEMBL18579804 | 0.67 | ALDH1A1 (0.49) | KDM4EGAATDP1ACHEALDH1A1 | |
| SCHEMBL1639345 | 0.67 | ALDH1A1 (0.47) | KDM4EGAAALDH1A1 | |
| SCHEMBL16426120 | 0.67 | LPL (0.44) | HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015086693-A1 | PYRAZOLOPYRIMIDIN-2-YL DERIVATIVES AS JAK INHIBITORS | ALMIRALL, S.A. (ES) | 2015-06-18 | — | — | WO | disclosed |