Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 6/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 6/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 6/20 | 0.35 |
| ▸ | BACE1 | P56817 | 6/20 | 0.35 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 4/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16795137 | 0.86 | ACHE (0.34) | CARM1PRMT6ACHEBACE1PRMT8 | |
| SCHEMBL16795329 | 0.84 | ALDH1A1 (0.43) | HRH3CYP2C9HIF1A | |
| SCHEMBL16795306 | 0.77 | CARM1 (0.47) | HRH3CARM1PRMT6CYP2C9ACHE | |
| SCHEMBL16795229 | 0.76 | CXCR3 (0.36) | ACHEBACE1BCHEHIF1A | |
| SCHEMBL16795178 | 0.76 | ALDH1A1 (0.37) | HRH3 | |
| SCHEMBL16795410 | 0.72 | L3MBTL3 (0.42) | — | |
| SCHEMBL18580408 | 0.70 | LPL (0.47) | CARM1PRMT6ACHEBACE1PRMT8 | |
| SCHEMBL18580127 | 0.69 | LPL (0.46) | HRH3CARM1PRMT6ACHEBACE1 | |
| SCHEMBL16795407 | 0.66 | KDM4E (0.44) | — | |
| SCHEMBL28690594 | 0.66 | HRH3 (0.53) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015086693-A1 | PYRAZOLOPYRIMIDIN-2-YL DERIVATIVES AS JAK INHIBITORS | ALMIRALL, S.A. (ES) | 2015-06-18 | — | — | WO | disclosed |