SCHEMBL16802474

SCHEMBL16802474

C#CCCCC(=O)N(C)C

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
CHRNB2 P17787 1/20 0.45
CHRNB4 P30926 1/20 0.45
CHRNA4 P43681 1/20 0.45
CYP1A2 P05177 2/20 0.45
CYP2D6 P10635 2/20 0.45
MAPT P10636 2/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
HSD17B10 Q99714 1/20 0.45
KDM4E B2RXH2 1/20 0.43
HPGD P15428 1/20 0.43
CYP3A4 P08684 2/20 0.38
ALOX5 P09917 1/20 0.38
PTGS1 P23219 1/20 0.38
PTGS2 P35354 1/20 0.38
LMNA P02545 1/20 0.34
MEN1 O00255 1/20 0.34
USP2 O75604 1/20 0.34
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL232706 0.86
SCHEMBL14392990 0.81 ALDH1A1 (0.43) ALDH1A1CYP1A2CYP2D6MAPTCYP2C9
SCHEMBL18075667 0.79 CYP1A2 (0.39) ALDH1A1CYP1A2CYP2D6MAPTCYP2C9
SCHEMBL11908759 0.78 LMNA (0.64) ALDH1A1CYP1A2CYP2D6MAPTCYP2C9
SCHEMBL965544 0.77 ALDH1A1 (0.54) ALDH1A1CHRNB2CHRNB4CHRNA4HSD17B10
SCHEMBL131476 0.77 ALDH1A1 (0.74) ALDH1A1CHRNB2CHRNB4CHRNA4ALOX5
SCHEMBL5948495 0.77 ALDH1A1 (0.74) ALDH1A1CHRNB2CHRNB4CHRNA4HSD17B10
SCHEMBL3189950 0.75 ALDH1A1 (0.70) ALDH1A1CHRNB2CHRNB4CHRNA4LMNA
SCHEMBL25416800 0.74 MAPT (0.47) ALDH1A1CYP1A2CYP2D6MAPTCYP2C9
SCHEMBL1415148 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4683672-A1 BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF Beone Medicines I GmbH (CH) 2026-01-28 EP disclosed
US-20260007761-A1 Bioactive Conjugate, Preparation Method Therefor and Use Thereof BEONE MEDICINES I GMBH (CH) 2026-01-08 US disclosed
WO-2024194851-A1 BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF BEIGENE SWITZERLAND GMBH (CH) 2024-09-26 WO disclosed
CN-112516179-A Dosing regimens and formulations for adenovirus type B 普赛奥克苏斯治疗公司 2021-03-19 CN disclosed
US-10727488-B2 Redox mediators for metal-sulfur batteries THE MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2020-07-28 US disclosed
US-10727488-B2 Redox mediators for metal-sulfur batteries THE MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2020-07-28 US disclosed
US-20180116983-A1 COMPOUNDS FOR TREATING DISORDERS ASSOCIATED WITH BK CHANNEL MODULATION CANBEX THERAPEUTICS LIMITED (GB) 2018-05-03 US disclosed
US-20180116983-A1 COMPOUNDS FOR TREATING DISORDERS ASSOCIATED WITH BK CHANNEL MODULATION CANBEX THERAPEUTICS LIMITED (GB) 2018-05-03 US disclosed
US-9908843-B2 Benzamide derivatives useful in the treatment of muscular disorders and pain and for controlling spasticity and tremors CANBEX THERAPEUTICS LIMITED (GB) 2018-03-06 US disclosed
US-9908843-B2 Benzamide derivatives useful in the treatment of muscular disorders and pain and for controlling spasticity and tremors CANBEX THERAPEUTICS LIMITED (GB) 2018-03-06 US disclosed
US-20170222226-A1 REDOX MEDIATORS FOR METAL-SULFUR BATTERIES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2017-08-03 US disclosed
US-20170222226-A1 REDOX MEDIATORS FOR METAL-SULFUR BATTERIES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2017-08-03 US disclosed
US-20170222226-A1 REDOX MEDIATORS FOR METAL-SULFUR BATTERIES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2017-08-03 US disclosed
US-20160304441-A1 BENZAMIDE DERIVATIVES USEFUL IN THE TREATMENT OF MUSCULAR DISORDERS AND PAIN AND FOR CONTROLLING SPASTICITY AND TREMORS UCL BUSINESS PLC (GB) 2016-10-20 US disclosed
US-20160304441-A1 BENZAMIDE DERIVATIVES USEFUL IN THE TREATMENT OF MUSCULAR DISORDERS AND PAIN AND FOR CONTROLLING SPASTICITY AND TREMORS UCL BUSINESS PLC (GB) 2016-10-20 US disclosed
WO-2016128771-A1 COMPOUNDS FOR TREATING DISORDERS ASSOCIATED WITH BK CHANNEL MODULATION CANBEX THERAPEUTICS LIMITED (GB) 2016-08-18 WO disclosed
CN-105793237-A Benzamide derivatives for the treatment of muscular disorders and pain and for the control of spasticity and tremors 坎贝克斯治疗有限公司 2016-07-20 CN disclosed
WO-2016025467-A1 REDOX MEDIATORS FOR METAL-SULFUR BATTERIES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-02-18 WO disclosed
WO-2016025467-A1 REDOX MEDIATORS FOR METAL-SULFUR BATTERIES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-02-18 WO disclosed
WO-2015082938-A1 BENZAMIDE DERIVATIVES USEFUL IN THE TREATMENT OF MUSCULAR DISORDERSAND PAIN AND FOR CONTROLLING SPASTICITY AND TREMORS CANBEX THERAPEUTICS LIMITED (GB) 2015-06-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260007761-A1 Bioactive Conjugate, Preparation Method Therefor and Use Thereof IGLV6-57, BCR, INCENP ALDH1A1 2110/4885CHRNB2 426/4885CHRNB4 803/4885
US-10727488-B2 Redox mediators for metal-sulfur batteries SQOR, NDUFS4, NDUFS3 ALDH1A1 1024/4885CHRNB2 3329/4885CHRNB4 2892/4885
US-20170222226-A1 REDOX MEDIATORS FOR METAL-SULFUR BATTERIES SQOR, NDUFS4, NDUFS3 ALDH1A1 1024/4885CHRNB2 3329/4885CHRNB4 2892/4885
US-20180116983-A1 COMPOUNDS FOR TREATING DISORDERS ASSOCIATED WITH BK CHANNEL MODULATION HCN4, KCNJ4, KCNQ4 ALDH1A1 3891/4885CHRNB2 199/4885CHRNB4 120/4885
US-20160304441-A1 BENZAMIDE DERIVATIVES USEFUL IN THE TREATMENT OF MUSCULAR DISORDERS AND PAIN AND FOR CONTROLLING SPASTICITY AND TREMORS MUSK, MYLK2, CBR3 ALDH1A1 3265/4885CHRNB2 94/4885CHRNB4 68/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.