Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDCBP | O00560 | 1/20 | 0.47 |
| ▸ | SDC2 | P34741 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | FPR3 | P25089 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12290721 | 0.83 | CYP17A1 (0.42) | NAMPTGAAMAPTALDH1A1HPGD | |
| SCHEMBL17026722 | 0.83 | ALDH1A1 (0.45) | L3MBTL1GAACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL17039174 | 0.80 | ACACB (0.50) | HDAC1MAPTTDP1ALDH1A1 | |
| SCHEMBL3180689 | 0.76 | L3MBTL1 (0.61) | SDCBPSDC2L3MBTL1NAMPTHDAC1 | |
| SCHEMBL17171415 | 0.76 | EPHX2 (0.57) | SDCBPSDC2L3MBTL1NAMPTHDAC1 | |
| SCHEMBL19654454 | 0.76 | L3MBTL1 (0.52) | SDCBPSDC2L3MBTL1NAMPTHDAC1 | |
| SCHEMBL314044 | 0.75 | MMP9 (0.44) | GAAMAPTALDH1A1 | |
| SCHEMBL11523954 | 0.75 | ALDH1A1 (0.52) | SDCBPSDC2L3MBTL1NAMPTHDAC1 | |
| SCHEMBL4616649 | 0.75 | MAPK14 (0.53) | L3MBTL1NAMPTHDAC1CA1CYP3A4 | |
| SCHEMBL11523953 | 0.75 | SDCBP (0.52) | SDCBPSDC2L3MBTL1NAMPTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10357546-B2 | Acceleration of diabetic wound healing | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2019-07-23 | — | — | US | disclosed |
| US-9951035-B2 | Selective matrix metalloproteinase inhibitors | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2018-04-24 | — | — | US | disclosed |
| US-20170274053-A1 | ACCELERATION OF DIABETIC WOUND HEALING | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2017-09-28 | — | — | US | disclosed |
| US-20170190685-A1 | SELECTIVE MATRIX METALLOPROTEINASE INHIBITORS | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2017-07-06 | — | — | US | disclosed |
| US-9604957-B2 | Selective matrix metalloproteinase inhibitors | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2017-03-28 | — | — | US | disclosed |
| US-20170015647-A1 | SELECTIVE MATRIX METALLOPROTEINASE INHIBITORS | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2017-01-19 | — | — | US | disclosed |
| WO-2016044844-A1 | ACCELERATION OF DIABETIC WOUND HEALING | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2016-03-24 | — | — | WO | disclosed |
| WO-2015127302-A1 | SELECTIVE MATRIX METALLOPROTEINASE INHIBITORS | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2015-08-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170274053-A1 | ACCELERATION OF DIABETIC WOUND HEALING | MMP8, MMP9, MMP1 | SDCBP 2587/4885SDC2 984/4885L3MBTL1 4328/4885 |
| US-20170190685-A1 | SELECTIVE MATRIX METALLOPROTEINASE INHIBITORS | MMP14, MMP9, MMP13 | SDCBP 4016/4885SDC2 834/4885L3MBTL1 3997/4885 |
| US-20170015647-A1 | SELECTIVE MATRIX METALLOPROTEINASE INHIBITORS | MMP14, MMP9, MMP13 | SDCBP 4016/4885SDC2 834/4885L3MBTL1 3997/4885 |
| US-10357546-B2 | Acceleration of diabetic wound healing | MMP8, MMP9, MMP1 | SDCBP 2587/4885SDC2 984/4885L3MBTL1 4328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.