SCHEMBL1712602

SCHEMBL1712602

CCCCCCC(C)(C)OC(=O)CCCCC(=O)OC(C)(C)CCCCCC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.52
LMNA P02545 2/20 0.48
PAM P19021 2/20 0.47
MAPT P10636 2/20 0.46
MAPK1 P28482 1/20 0.46
CES2 O00748 3/20 0.45
CES1 P23141 3/20 0.45
TSHR P16473 5/20 0.44
PPARG P37231 6/20 0.43
PPARD Q03181 6/20 0.43
PPARA Q07869 6/20 0.43
HDAC11 Q96DB2 5/20 0.43
GPR84 Q9NQS5 4/20 0.43
ALDH1A1 P00352 2/20 0.43
TLR2 O60603 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
FABP4 P15090 2/20 0.43
PTPN1 P18031 2/20 0.43
SLC22A6 Q4U2R8 1/20 0.43
SLC22A8 Q8TCC7 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29227001 1.00 DGKA (0.52) DGKALMNAPAMMAPTMAPK1
SCHEMBL8041219 1.00 DGKA (0.52) DGKALMNAPAMMAPTMAPK1
SCHEMBL28949803 1.00 DGKA (0.52) DGKALMNAPAMMAPTMAPK1
SCHEMBL28949796 1.00 DGKA (0.52) DGKALMNAPAMMAPTMAPK1
SCHEMBL11687288 0.98 DGKA (0.50) DGKALMNAPAMMAPTMAPK1
Ammonia Solution, Strong SCHEMBL9150921 0.98 DGKA (0.50) DGKALMNAPAMMAPTMAPK1
SCHEMBL20918464 0.96 DGKA (0.52) DGKALMNAPAMMAPTMAPK1
SCHEMBL17123453 0.95 DGKA (0.47) DGKALMNAPAMMAPTMAPK1
SCHEMBL18473868 0.95 DGKA (0.47) DGKALMNAPAMMAPTMAPK1
SCHEMBL11820606 0.94 PAM (0.48) DGKALMNAPAMMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2178491-B1 MIXTURES COMPRISING BENZOTRIAZOLES AND MEROCYANINES BASF SE (DE) 2017-03-22 EP disclosed
EP-2016059-B1 TRIAZINE DERIVATIVES BASF SE (DE) 2016-12-07 EP disclosed
US-20130251650-A1 MIXTURES COMPRISING BENZOTRIAZOLES AND MEROCYANINES BASF SE (DE) 2013-09-26 US disclosed
US-8454940-B2 Mixtures comprising benzotriazoles and merocyanines BASF SE (DE) 2013-06-04 US disclosed
US-8444879-B2 Triazine derivatives BASF SE (DE) 2013-05-21 US disclosed
EP-2120854-B1 STABILIZATION OF UV-SENSITIVE ACTIVE INGREDIENTS BASF SE (DE) 2012-12-26 EP disclosed
EP-2344112-A1 SUNSCREEN AND PERSONAL CARE COMPOSITIONS COMPRISING A RANDOM TERPOLYMER BASF SE (DE) 2011-07-20 EP disclosed
EP-2340088-A2 COLOR COSMETIC COMPRISING A RANDOM TERPOLYMER BASF SE (DE) 2011-07-06 EP disclosed
US-20100129303-A1 SUNSCREEN AND PERSONAL CARE COMPOSITIONS COMPRISING A RANDOM TERPOLYMER BASF SE (DE) 2010-05-27 US disclosed
US-20100104610-A1 Color cosmetics comprising a random terpolymer BASF SE (DE) 2010-04-29 US disclosed
WO-2010043588-A1 SUNSCREEN AND PERSONAL CARE COMPOSITIONS COMPRISING A RANDOM TERPOLYMER BASF SE (DE) 2010-04-22 WO disclosed
EP-2152230-A2 SUNSCREEN COMPOSTIONS COMPRISING A RANDOM TERPOLYMER BASF SE (DE) 2010-02-17 EP disclosed
EP-2129363-A2 SUNSCREEN AND PERSONAL CARE COMPOSITIONS COMPRISING A SELECT COPOLYMER BASF SE (DE) 2009-12-09 EP disclosed
US-20090124576-A1 Triazine Derivatives BASF SE (DE) 2009-05-14 US disclosed
EP-2005940-A2 Higher performance capsule particles INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) 2008-12-24 EP disclosed
US-20080311064-A1 Higher Performance Capsule Particles INTERNATIONAL FLAVORS & FRAGRANCES INC. 2008-12-18 US disclosed
WO-2008122516-A2 SUNSCREEN AND PERSONAL CARE COMPOSITIONS COMPRISING A SELECT COPOLYMER BASF SE (CH) 2008-10-16 WO disclosed
WO-2008122517-A2 SUNSCREEN COMPOSITIONS COMPRISING A RANDOM TERPOLYMER BASF SE (CH) 2008-10-16 WO disclosed
US-20080247976-A1 water-resistant cosmetic or dermatological compositions for the UV-photoprotection of human skin and/or hair with enhanced stability to water DUEVA-KOGANOV OLGA V 2008-10-09 US disclosed
US-20080247975-A1 Sunscreen and personal care compositions comprising a select copolymer CIBA CORP. 2008-10-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080247976-A1 water-resistant cosmetic or dermatological compositions for the UV-photoprotection of human skin and/or hair with enhanced stability to water CUTA, POLR1C, MSH6 DGKA 1574/4885LMNA 598/4885PAM 3871/4885
US-20080311064-A1 Higher Performance Capsule Particles PFKP, GYS1, GYS2 DGKA 1045/4885LMNA 3220/4885PAM 1523/4885
US-20090124576-A1 Triazine Derivatives MSR1, NR1H2, NR1H3 DGKA 4255/4885LMNA 1949/4885PAM 829/4885
US-20100129303-A1 SUNSCREEN AND PERSONAL CARE COMPOSITIONS COMPRISING A RANDOM TERPOLYMER MITF, TYR, MSH6 DGKA 3941/4885LMNA 2909/4885PAM 1889/4885
US-20080247975-A1 Sunscreen and personal care compositions comprising a select copolymer MSH6, CUTA, ERCC5 DGKA 3145/4885LMNA 1080/4885PAM 1857/4885
US-20100104610-A1 Color cosmetics comprising a random terpolymer CUTA, TYR, MSH6 DGKA 763/4885LMNA 2401/4885PAM 4564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.