SCHEMBL1712604

SCHEMBL1712604

CCCCCCC(C)(C)OC(=O)CCCCC(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.57
PPARG P37231 7/20 0.57
PPARD Q03181 7/20 0.57
PPARA Q07869 7/20 0.57
HDAC11 Q96DB2 5/20 0.57
TSHR P16473 4/20 0.57
PTPN1 P18031 3/20 0.57
FABP4 P15090 3/20 0.57
ALDH1A1 P00352 2/20 0.57
TLR2 O60603 2/20 0.57
TDP1 Q9NUW8 2/20 0.57
KMT2A Q03164 2/20 0.57
ALOX15 P16050 2/20 0.57
HSD17B10 Q99714 2/20 0.57
SLC22A6 Q4U2R8 1/20 0.57
SLC22A8 Q8TCC7 1/20 0.57
MEN1 O00255 1/20 0.57
ESR1 P03372 1/20 0.57
PDE4A P27815 1/20 0.57
PDE3A Q14432 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28949796 0.93 DGKA (0.52) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL8041219 0.93 DGKA (0.52) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL1712602 0.93 DGKA (0.52) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL29227001 0.93 DGKA (0.52) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL28949803 0.93 DGKA (0.52) GPR84PPARGPPARDPPARAHDAC11
Ammonia Solution, Strong SCHEMBL9150921 0.91 DGKA (0.50) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL11687288 0.91 DGKA (0.50) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL26978207 0.90 TSHR (0.47) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL20918464 0.90 DGKA (0.52) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL690625 0.88 GPR84 (0.59) GPR84PPARGPPARDPPARAHDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2178491-B1 MIXTURES COMPRISING BENZOTRIAZOLES AND MEROCYANINES BASF SE (DE) 2017-03-22 EP disclosed
EP-2016059-B1 TRIAZINE DERIVATIVES BASF SE (DE) 2016-12-07 EP disclosed
CN-101711151-B Stabilization of UV-sensitive active ingredients CIBA HOLDING INC 2013-12-18 CN disclosed
US-20130251650-A1 MIXTURES COMPRISING BENZOTRIAZOLES AND MEROCYANINES BASF SE (DE) 2013-09-26 US disclosed
US-8454940-B2 Mixtures comprising benzotriazoles and merocyanines BASF SE (DE) 2013-06-04 US disclosed
US-8444879-B2 Triazine derivatives BASF SE (DE) 2013-05-21 US disclosed
EP-2120854-B1 STABILIZATION OF UV-SENSITIVE ACTIVE INGREDIENTS BASF SE (DE) 2012-12-26 EP disclosed
CN-102227238-A Color cosmetics containing random terpolymer BASF SE 2011-10-26 CN disclosed
CN-102186452-A Sunscreen and personal care compositions comprising a random terpolymer BASF SE 2011-09-14 CN disclosed
EP-2344112-A1 SUNSCREEN AND PERSONAL CARE COMPOSITIONS COMPRISING A RANDOM TERPOLYMER BASF SE (DE) 2011-07-20 EP disclosed
CN-101677938-A Sunscreen compositions comprising random terpolymers BASF SE 2010-03-24 CN disclosed
EP-2152230-A2 SUNSCREEN COMPOSTIONS COMPRISING A RANDOM TERPOLYMER BASF SE (DE) 2010-02-17 EP disclosed
EP-2129363-A2 SUNSCREEN AND PERSONAL CARE COMPOSITIONS COMPRISING A SELECT COPOLYMER BASF SE (DE) 2009-12-09 EP disclosed
US-20090124576-A1 Triazine Derivatives BASF SE (DE) 2009-05-14 US disclosed
EP-2005940-A2 Higher performance capsule particles INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) 2008-12-24 EP disclosed
US-20080311064-A1 Higher Performance Capsule Particles INTERNATIONAL FLAVORS & FRAGRANCES INC. 2008-12-18 US disclosed
WO-2008122516-A2 SUNSCREEN AND PERSONAL CARE COMPOSITIONS COMPRISING A SELECT COPOLYMER BASF SE (CH) 2008-10-16 WO disclosed
WO-2008122517-A2 SUNSCREEN COMPOSITIONS COMPRISING A RANDOM TERPOLYMER BASF SE (CH) 2008-10-16 WO disclosed
US-20080247976-A1 water-resistant cosmetic or dermatological compositions for the UV-photoprotection of human skin and/or hair with enhanced stability to water DUEVA-KOGANOV OLGA V 2008-10-09 US disclosed
US-20080247975-A1 Sunscreen and personal care compositions comprising a select copolymer CIBA CORP. 2008-10-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080247976-A1 water-resistant cosmetic or dermatological compositions for the UV-photoprotection of human skin and/or hair with enhanced stability to water CUTA, POLR1C, MSH6 GPR84 4328/4885PPARG 1485/4885PPARD 1229/4885
US-20080311064-A1 Higher Performance Capsule Particles PFKP, GYS1, GYS2 GPR84 625/4885PPARG 502/4885PPARD 417/4885
US-20090124576-A1 Triazine Derivatives MSR1, NR1H2, NR1H3 GPR84 199/4885PPARG 2126/4885PPARD 2575/4885
US-20080247975-A1 Sunscreen and personal care compositions comprising a select copolymer MSH6, CUTA, ERCC5 GPR84 4089/4885PPARG 1261/4885PPARD 1220/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.