SCHEMBL17186

SCHEMBL17186

C=CCOC[C@H](O)[C@@H](O)[C@H](O)CO

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.48
CA2 P00918 3/20 0.48
CA7 P43166 2/20 0.48
CA9 Q16790 2/20 0.41
LMNA P02545 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
CA4 P22748 1/20 0.31
KDM4E B2RXH2 2/20 0.30
PDE4A P27815 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3970966 1.00 CA1 (0.48) CA1CA2CA7CA9LMNA
SCHEMBL10587296 1.00 CA1 (0.48) CA1CA2CA7CA9LMNA
SCHEMBL8373146 1.00 CA1 (0.48) CA1CA2CA7CA9LMNA
SCHEMBL2863103 0.96 CA1 (0.48) CA1CA2CA7CA9LMNA
SCHEMBL657952 0.96 CA1 (0.48) CA1CA2CA7CA9LMNA
SCHEMBL11059349 0.96 CA1 (0.48) CA1CA2CA7CA9LMNA
Ethylene Glycol SCHEMBL28198773 0.92 CA1 (0.46) CA1CA2CA7CA9LMNA
Xylitol SCHEMBL3293322 0.89 LMNA (0.46) CA1CA2CA7CA9LMNA
Adonitol SCHEMBL3970962 0.89 LMNA (0.46) CA1CA2CA7CA9LMNA
Phosphoric Acid SCHEMBL2859329 0.87 CA1 (0.42) CA1CA2CA7CA9LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108951169-B Preparation method of natural alcohol ether modified organosilicon hydrophilic softening agent 杭州美高华颐化工有限公司 2021-02-09 CN claimed
US-8138248-B2 Method to improve cold flow resistance of polymers BRIDGESTONE CORPORATION (JP) 2012-03-20 US claimed
CN-101925349-A Orally disintegrating tablet composition of temazepam EURAND INC 2010-12-22 CN claimed
US-20100004361-A1 METHOD TO IMPROVE COLD FLOW RESISTANCE OF POLYMERS BRIDGESTONE CORPORATION (JP) 2010-01-07 US claimed
WO-2009086046-A1 ORALLY DISINTEGRATING TABLET COMPOSITIONS OF TEMAZEPAM EURAND, INC. (US) 2009-07-09 WO claimed
US-20090169620-A1 ORALLY DISINTEGRATING TABLET COMPOSITIONS OF TEMAZEPAM ADARE DEVELOPMENT I, L.P. 2009-07-02 US claimed
CN-111971025-B Cross-linking compositions, personal care compositions comprising the same and methods of forming 美国陶氏有机硅公司 2023-06-09 CN disclosed
EP-2492301-B1 NOVEL CO-MODIFIED ORGANOPOLYSILOXANE DOW TORAY CO LTD (JP) 2023-03-29 EP disclosed
EP-3787594-B1 CROSS-LINKED COMPOSITION, PERSONAL CARE COMPOSITION INCLUDING THE SAME, AND METHODS OF FORMATION DOW SILICONES CORP (US) 2022-08-31 EP disclosed
CN-109745244-B Whitening essence 西安博鸿生物技术有限公司 2021-12-24 CN disclosed
CN-107690329-B Pituitous silicone emulsions 美国陶氏有机硅公司 2021-10-08 CN disclosed
US-20210236409-A1 CROSS-LINKED COMPOSITION, PERSONAL CARE COMPOSITION INCLUDING THE SAME, AND METHODS OF FORMATION DOW SILICONES CORP (US) 2021-08-05 US disclosed
EP-3448974-B1 DETERGENT COMPOSITION COMPRISING A CARBINOL FUNCTIONAL TRISILOXANE DOW SILICONES CORP (US) 2021-07-07 EP disclosed
US-7157510-B2 Method of nucleating a polyolefin composition with acetal-based compounds MILLIKEN & COMPANY (US) 2007-01-02 US disclosed
WO-2006044187-A1 A METHOD FOR PREPARING ACETAL-CONTAINING COMPOSITIONS AND RELATED COMPOSITIONS AND ARTICLES MILLIKEN & COMPANY (US) 2006-04-27 WO disclosed
US-20060079720-A1 Method for preparing acetal-containing compositions MILLIKEN & COMPANY 2006-04-13 US disclosed
WO-2005111134-A2 METHOD OF NUCLEATING A POLYOLEFIN COMPOSITION WITH ACETAL-BASED COMPOUNDS MILLIKEN & COMPANY (US) 2005-11-24 WO disclosed
WO-2005108479-A2 ACETAL-BASED COMPOSITIONS MILLIKEN & COMPANY (US) 2005-11-17 WO disclosed
US-20050239928-A1 Acetal-based compositions MILLIKEN & COMPANY 2005-10-27 US disclosed
US-20050239926-A1 Method of nucleating a polyolefin composition with acetal-based compounds MILLIKEN & COMPANY 2005-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210236409-A1 CROSS-LINKED COMPOSITION, PERSONAL CARE COMPOSITION INCLUDING THE SAME, AND METHODS OF FORMATION PLOD2, PLOD1, PLOD3 CA1 202/4885CA2 425/4885CA7 20/4885
US-20090169620-A1 ORALLY DISINTEGRATING TABLET COMPOSITIONS OF TEMAZEPAM SORD, GABRQ, KCNT1 CA1 1353/4885CA2 2476/4885CA7 1929/4885
US-20050239928-A1 Acetal-based compositions PCNA, RAD51, AR CA1 1596/4885CA2 2980/4885CA7 961/4885
US-20060079720-A1 Method for preparing acetal-containing compositions ADH1C, ME1, ADH5 CA1 27/4885CA2 276/4885CA7 87/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.