SCHEMBL17278526

SCHEMBL17278526

CC1(C)c2ccccc2N(c2ccc3c(c2)Oc2ccccc2N3c2ccc(-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)cc2)c2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.32
▸ MAPT P10636 2/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32
▸ NPSR1 Q6W5P4 1/20 0.32
▸ MEN1 O00255 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ HPGD P15428 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ EGLN1 Q9GZT9 3/20 0.31
▸ P2RX4 Q99571 1/20 0.30
▸ ADAMTS5 Q9UNA0 1/20 0.30
▸ CDK8 P49336 1/20 0.30
▸ ADORA2A P29274 1/20 0.30
▸ ADORA1 P30542 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17278587 0.95 L3MBTL1 (0.32) POLBL3MBTL1MAPTMEN1ALDH1A1
SCHEMBL17278673 0.94 L3MBTL1 (0.36) POLBL3MBTL1MAPTSMN1; SMN2MEN1
SCHEMBL17278674 0.93 L3MBTL1 (0.35) POLBL3MBTL1MAPTSMN1; SMN2MEN1
SCHEMBL17278509 0.92 ADORA2A (0.33) POLBL3MBTL1MAPTSMN1; SMN2NPSR1
SCHEMBL17278584 0.92 ADORA2A (0.33) POLBL3MBTL1MAPTSMN1; SMN2NPSR1
SCHEMBL17278707 0.92 TRPV4 (0.33) POLBL3MBTL1MAPTSMN1; SMN2NPSR1
SCHEMBL17278705 0.92 TRPV4 (0.33) POLBL3MBTL1MAPTSMN1; SMN2NPSR1
SCHEMBL17278510 0.90 MEN1 (0.37) POLBL3MBTL1MAPTSMN1; SMN2NPSR1
SCHEMBL20230569 0.88 POLB (0.33) POLBL3MBTL1MAPTSMN1; SMN2MEN1
SCHEMBL20230605 0.88 POLB (0.35) POLBL3MBTL1MAPTSMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11730052-B2 Light-emitting device IDEMITSU KOSAN CO., LTD. (JP) 2023-08-15 — — US disclosed
US-11730052-B2 Light-emitting device IDEMITSU KOSAN CO., LTD. (JP) 2023-08-15 — — US disclosed
US-20190109285-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2019-04-11 — — US disclosed
US-10186665-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2019-01-22 — — US disclosed
US-9882144-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-01-30 — — US disclosed
US-9882144-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-01-30 — — US disclosed
US-20170244049-A1 ORGANIC LIGHT-EMITTING DIODE MATERIALS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2017-08-24 — — US disclosed
US-20160197287-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 — — US disclosed
US-20160197287-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 — — US disclosed
US-20160028025-A1 LIGHT-EMITTING DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-01-28 — — US disclosed
US-20160028025-A1 LIGHT-EMITTING DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-01-28 — — US disclosed
US-20150340623-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-11-26 — — US disclosed
US-20150340623-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-11-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190109285-A1 ORGANIC ELECTROLUMINESCENT ELEMENT TCF4, TRPA1, EML4 POLB 1106/4885L3MBTL1 737/4885MAPT 1068/4885
US-20170244049-A1 ORGANIC LIGHT-EMITTING DIODE MATERIALS CYBA, DDT, DRD1 POLB 958/4885L3MBTL1 24/4885MAPT 640/4885
US-11730052-B2 Light-emitting device GRK7, GRK1, CTNND1 POLB 2477/4885L3MBTL1 566/4885MAPT 1228/4885
US-10186665-B2 Organic electroluminescent element TCF4, TRPA1, EML4 POLB 1106/4885L3MBTL1 737/4885MAPT 1068/4885
US-20160197287-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AOC2, AZI2, RER1 POLB 2874/4885L3MBTL1 2484/4885MAPT 3937/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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