SCHEMBL17278705

SCHEMBL17278705

CC1(C)c2ccccc2N(c2ccc(-c3nc(-c4ccc(N5c6ccccc6Oc6ccccc65)cc4)nc(-c4ccc(N5c6ccccc6Oc6ccccc65)cc4)n3)cc2)c2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TRPV4 Q9HBA0 1/20 0.33
▸ KMT2A Q03164 3/20 0.32
▸ MAPT P10636 3/20 0.32
▸ MEN1 O00255 2/20 0.32
▸ SMN1; SMN2 Q16637 2/20 0.32
▸ HTT P42858 2/20 0.32
▸ NPC1 O15118 1/20 0.32
▸ USP2 O75604 1/20 0.32
▸ POLB P06746 1/20 0.32
▸ RAB9A P51151 1/20 0.32
▸ P2RX4 Q99571 6/20 0.32
▸ CYP1A2 P05177 1/20 0.32
▸ CYP2D6 P10635 1/20 0.32
▸ ALDH1A1 P00352 2/20 0.32
▸ ALPG P10696 1/20 0.32
▸ THRB P10828 1/20 0.32
▸ TDP1 Q9NUW8 1/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.31
▸ PGR P06401 4/20 0.31
▸ NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17278707 1.00 TRPV4 (0.33) TRPV4KMT2AMAPTMEN1SMN1; SMN2
SCHEMBL17278673 0.97 L3MBTL1 (0.36) TRPV4KMT2AMAPTMEN1SMN1; SMN2
SCHEMBL17278674 0.96 L3MBTL1 (0.35) TRPV4KMT2AMAPTMEN1SMN1; SMN2
SCHEMBL17278526 0.92 POLB (0.33) KMT2AMAPTMEN1SMN1; SMN2POLB
SCHEMBL17278708 0.92 HDAC6 (0.39) —
SCHEMBL17278587 0.92 L3MBTL1 (0.32) KMT2AMAPTMEN1POLBP2RX4
SCHEMBL17278593 0.91 KMT2A (0.36) TRPV4KMT2AMAPTMEN1HTT
SCHEMBL17471203 0.91 TRPV4 (0.31) TRPV4
SCHEMBL17279260 0.91 PGR (0.43) USP2POLBPGR
SCHEMBL17278678 0.89 PGR (0.33) KMT2AMAPTMEN1SMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11730052-B2 Light-emitting device IDEMITSU KOSAN CO., LTD. (JP) 2023-08-15 — — US disclosed
US-11730052-B2 Light-emitting device IDEMITSU KOSAN CO., LTD. (JP) 2023-08-15 — — US disclosed
US-20190109285-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2019-04-11 — — US disclosed
US-10186665-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2019-01-22 — — US disclosed
US-9882144-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-01-30 — — US disclosed
US-9882144-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-01-30 — — US disclosed
US-20160197287-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 — — US disclosed
US-20160197287-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 — — US disclosed
US-20160028025-A1 LIGHT-EMITTING DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-01-28 — — US disclosed
US-20160028025-A1 LIGHT-EMITTING DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-01-28 — — US disclosed
US-20150340623-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-11-26 — — US disclosed
US-20150340623-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-11-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190109285-A1 ORGANIC ELECTROLUMINESCENT ELEMENT TCF4, TRPA1, EML4 TRPV4 5/4885KMT2A 1347/4885MAPT 1068/4885
US-11730052-B2 Light-emitting device GRK7, GRK1, CTNND1 TRPV4 1423/4885KMT2A 3535/4885MAPT 1228/4885
US-10186665-B2 Organic electroluminescent element TCF4, TRPA1, EML4 TRPV4 5/4885KMT2A 1347/4885MAPT 1068/4885
US-20160197287-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AOC2, AZI2, RER1 TRPV4 2844/4885KMT2A 1282/4885MAPT 3937/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback