SCHEMBL17278683

SCHEMBL17278683

CC1(C)c2ccccc2N(c2cc(-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)cc(N3c4ccccc4Oc4ccccc43)c2)c2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ ADAMTS5 Q9UNA0 2/20 0.34
▸ ITGB2 P05107 1/20 0.32
▸ ICAM1 P05362 1/20 0.32
▸ ITGAL P20701 1/20 0.32
▸ P2RX4 Q99571 1/20 0.32
▸ POLB P06746 4/20 0.31
▸ MAPT P10636 5/20 0.31
▸ KDM4E B2RXH2 3/20 0.31
▸ ALDH1A1 P00352 2/20 0.31
▸ SMN1; SMN2 Q16637 2/20 0.31
▸ NPSR1 Q6W5P4 1/20 0.31
▸ MEN1 O00255 3/20 0.31
▸ KMT2A Q03164 3/20 0.31
▸ HTT P42858 3/20 0.31
▸ HPGD P15428 2/20 0.31
▸ PSMD14 O00487 1/20 0.31
▸ CYP1A2 P05177 1/20 0.31
▸ CYP3A4 P08684 1/20 0.31
▸ CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17278685 0.98 ADAMTS5 (0.33) L3MBTL1ADAMTS5ITGB2ICAM1ITGAL
SCHEMBL17278686 0.98 ADAMTS5 (0.33) L3MBTL1ADAMTS5ITGB2ICAM1ITGAL
SCHEMBL17278691 0.93 MEN1 (0.35) L3MBTL1ADAMTS5ITGB2ICAM1ITGAL
SCHEMBL13231651 0.92 L3MBTL1 (0.40) L3MBTL1ADAMTS5ITGB2ICAM1ITGAL
SCHEMBL17278697 0.92 MEN1 (0.37) ADAMTS5MAPTKDM4EALDH1A1NPSR1
SCHEMBL17278690 0.91 MEN1 (0.36) L3MBTL1ADAMTS5MAPTKDM4EALDH1A1
SCHEMBL17278673 0.90 L3MBTL1 (0.36) L3MBTL1ADAMTS5P2RX4POLBMAPT
SCHEMBL13231684 0.90 L3MBTL1 (0.38) L3MBTL1ADAMTS5ITGB2ICAM1ITGAL
SCHEMBL17278601 0.90 L3MBTL1 (0.38) L3MBTL1ADAMTS5ITGB2ICAM1ITGAL
SCHEMBL17278602 0.90 L3MBTL1 (0.38) L3MBTL1ADAMTS5ITGB2ICAM1ITGAL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11730052-B2 Light-emitting device IDEMITSU KOSAN CO., LTD. (JP) 2023-08-15 — — US disclosed
US-11730052-B2 Light-emitting device IDEMITSU KOSAN CO., LTD. (JP) 2023-08-15 — — US disclosed
US-20190109285-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2019-04-11 — — US disclosed
US-10186665-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2019-01-22 — — US disclosed
US-9882144-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-01-30 — — US disclosed
US-9882144-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-01-30 — — US disclosed
US-20160197287-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 — — US disclosed
US-20160197287-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 — — US disclosed
US-20160028025-A1 LIGHT-EMITTING DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-01-28 — — US disclosed
US-20160028025-A1 LIGHT-EMITTING DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-01-28 — — US disclosed
US-20150340623-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-11-26 — — US disclosed
US-20150340623-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-11-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190109285-A1 ORGANIC ELECTROLUMINESCENT ELEMENT TCF4, TRPA1, EML4 L3MBTL1 737/4885ADAMTS5 4577/4885ITGB2 794/4885
US-11730052-B2 Light-emitting device GRK7, GRK1, CTNND1 L3MBTL1 566/4885ADAMTS5 4860/4885ITGB2 1082/4885
US-10186665-B2 Organic electroluminescent element TCF4, TRPA1, EML4 L3MBTL1 737/4885ADAMTS5 4577/4885ITGB2 794/4885
US-20160197287-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AOC2, AZI2, RER1 L3MBTL1 2484/4885ADAMTS5 4864/4885ITGB2 508/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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