SCHEMBL17278685

SCHEMBL17278685

CC1(C)c2ccccc2N(c2cc(-c3nc(-c4ccccc4)nc(-c4ccc(-c5ccccc5)cc4)n3)cc(N3c4ccccc4Oc4ccccc43)c2)c2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ ADAMTS5 Q9UNA0 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ MEN1 O00255 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ HPGD P15428 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ ITGB2 P05107 1/20 0.31
▸ ICAM1 P05362 1/20 0.31
▸ ITGAL P20701 1/20 0.31
▸ P2RX4 Q99571 1/20 0.31
▸ ADORA2A P29274 1/20 0.30
▸ ADORA1 P30542 1/20 0.30
▸ POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17278686 1.00 ADAMTS5 (0.33) ADAMTS5L3MBTL1MEN1ALDH1A1MAPT
SCHEMBL17278683 0.98 L3MBTL1 (0.34) ADAMTS5L3MBTL1MEN1ALDH1A1MAPT
SCHEMBL17278690 0.93 MEN1 (0.36) ADAMTS5L3MBTL1MEN1ALDH1A1MAPT
SCHEMBL17278601 0.93 L3MBTL1 (0.38) ADAMTS5L3MBTL1MEN1ALDH1A1MAPT
SCHEMBL17278602 0.93 L3MBTL1 (0.38) ADAMTS5L3MBTL1MEN1ALDH1A1MAPT
SCHEMBL17278702 0.92 MEN1 (0.38) ADAMTS5L3MBTL1MEN1ALDH1A1MAPT
SCHEMBL17278674 0.91 L3MBTL1 (0.35) ADAMTS5L3MBTL1MEN1ALDH1A1MAPT
SCHEMBL17278691 0.91 MEN1 (0.35) ADAMTS5L3MBTL1MEN1ALDH1A1MAPT
SCHEMBL17278673 0.90 L3MBTL1 (0.36) ADAMTS5L3MBTL1MEN1ALDH1A1MAPT
SCHEMBL13231651 0.90 L3MBTL1 (0.40) ADAMTS5L3MBTL1MEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11730052-B2 Light-emitting device IDEMITSU KOSAN CO., LTD. (JP) 2023-08-15 — — US disclosed
US-11730052-B2 Light-emitting device IDEMITSU KOSAN CO., LTD. (JP) 2023-08-15 — — US disclosed
US-20190109285-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2019-04-11 — — US disclosed
US-10186665-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2019-01-22 — — US disclosed
US-9882144-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-01-30 — — US disclosed
US-9882144-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-01-30 — — US disclosed
US-20160197287-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 — — US disclosed
US-20160197287-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 — — US disclosed
US-20160028025-A1 LIGHT-EMITTING DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-01-28 — — US disclosed
US-20160028025-A1 LIGHT-EMITTING DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-01-28 — — US disclosed
US-20150340623-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-11-26 — — US disclosed
US-20150340623-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-11-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190109285-A1 ORGANIC ELECTROLUMINESCENT ELEMENT TCF4, TRPA1, EML4 ADAMTS5 4577/4885L3MBTL1 737/4885MEN1 2279/4885
US-11730052-B2 Light-emitting device GRK7, GRK1, CTNND1 ADAMTS5 4860/4885L3MBTL1 566/4885MEN1 3144/4885
US-10186665-B2 Organic electroluminescent element TCF4, TRPA1, EML4 ADAMTS5 4577/4885L3MBTL1 737/4885MEN1 2279/4885
US-20160197287-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AOC2, AZI2, RER1 ADAMTS5 4864/4885L3MBTL1 2484/4885MEN1 886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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