Sugi Predict

Sugi Predict / Compounds / SCHEMBL17280200

SCHEMBL17280200

SCHEMBL17280200

O=Cc1ccccc1-c1cc(-c2cccc(-c3c[nH]c(-c4ccccc4C=O)c3)c2)c[nH]1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ THRB P10828 2/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ LMNA P02545 1/20 0.38
▸ BLM P54132 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.38
▸ XDH P47989 1/20 0.37
▸ CYP2A6 P11509 2/20 0.35
▸ IMPDH2 P12268 1/20 0.35
▸ ERN1 O75460 5/20 0.35
▸ GRM5 P41594 1/20 0.33
▸ AURKA O14965 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ CASP1 P29466 1/20 0.33
▸ TTK P33981 1/20 0.33
▸ AURKB Q96GD4 1/20 0.33
▸ INCENP Q9NQS7 1/20 0.33
▸ KMO O15229 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22242491 0.76 MCL1 (0.36) XDHALDH1A1
SCHEMBL19154057 0.75 MEN1 (0.46) NPC1RAB9ATHRBMEN1LMNA
SCHEMBL17279937 0.75 ALOX15 (0.51) NPC1RAB9AMEN1LMNAKMT2A
SCHEMBL5711323 0.72 LMNA (0.57) NPC1RAB9ATHRBMEN1LMNA
SCHEMBL17280182 0.71 AURKA (0.46) NPC1THRBMEN1KMT2AAURKA
SCHEMBL782416 0.70 ALDH1A1 (0.44) NPC1RAB9ATHRBMEN1LMNA
SCHEMBL17280164 0.70 NUDT1 (0.35) ALDH1A1
SCHEMBL17279777 0.69 AURKA (0.47) NPC1THRBMEN1KMT2AAURKA
SCHEMBL17280199 0.69 ADORA3 (0.43) MEN1LMNABLMKMT2ATDP1
SCHEMBL17280196 0.69 BRD4 (0.51) GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180203175-A1 TRIAZOLE COMPOUND Konica Minolta, Inc. (JP) 2018-07-19 — — US disclosed
US-20180203175-A1 TRIAZOLE COMPOUND Konica Minolta, Inc. (JP) 2018-07-19 — — US disclosed
US-10012777-B2 Resin composition Konica Minolta, Inc. (JP) 2018-07-03 — — US disclosed
US-10012777-B2 Resin composition Konica Minolta, Inc. (JP) 2018-07-03 — — US disclosed
WO-2017099041-A1 POLYIMIDE FILM, FLEXIBLE PRINTED BOARD, LED LIGHTING DEVICE ETC. コニカミノルタ株式会社 2017-06-15 — — WO disclosed
US-20150338563-A1 RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE KONICA MINOLTA, INC (JP) 2015-11-26 — — US disclosed
US-20150338563-A1 RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE KONICA MINOLTA, INC (JP) 2015-11-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150338563-A1 RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE HRH3, HELZ, NBAS NPC1 2503/4885RAB9A 1803/4885THRB 3045/4885
US-10012777-B2 Resin composition NBAS, WDR5, HRH3 NPC1 2768/4885RAB9A 2127/4885THRB 3805/4885
US-20180203175-A1 TRIAZOLE COMPOUND H1-10, TTI2, H1-2 NPC1 2718/4885RAB9A 1962/4885THRB 1319/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.