SCHEMBL1730486

SCHEMBL1730486

Clc1cccc2c1CC1C3C=CC(C3)C21

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TRPM5 Q9NZQ8 1/20 0.35
HTR2C P28335 2/20 0.33
HTR2A P28223 1/20 0.32
HTR2B P41595 1/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
ALDH1A1 P00352 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TRPA1 O75762 2/20 0.31
TSHR P16473 1/20 0.31
TP53 P04637 1/20 0.31
RECQL P46063 1/20 0.31
LMNA P02545 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1730421 0.80 KDM4E (0.35) HTR2CHTR2AHTR2BALDH1A1MEN1
SCHEMBL4403294 0.76 CYP19A1 (0.44) HTR2AALDH1A1MEN1KMT2A
SCHEMBL10068328 0.76 MEN1 (0.31) MEN1KMT2ALMNA
SCHEMBL29370901 0.72 KDM1A (0.52)
SCHEMBL413013 0.72 KDM1A (0.52)
SCHEMBL22209826 0.70 HTR2C (0.36) TRPM5HTR2CHTR2AHTR2BTRPA1
SCHEMBL4443404 0.68
SCHEMBL4403405 0.68 MEN1 (0.39) HTR2CHTR2AHTR2BALDH1A1MEN1
SCHEMBL8057369 0.66 DPP4 (0.42) HTR2CHTR2AHTR2BSMN1; SMN2ALDH1A1
SCHEMBL4403306 0.65 MTNR1A (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12595359-B2 Resin composition for forming optical component, molded product, and optical component MITSUI CHEMICALS, INC. (JP) 2026-04-07 US disclosed
US-12509489-B2 Oligopeptide ZEON CORPORATION (JP) 2025-12-30 US disclosed
US-20250179232-A1 RESIN COMPOSITION, MOLDED PRODUCT, AND OPTICAL MEMBER ZEON CORPORATION (JP) 2025-06-05 US disclosed
WO-2025100415-A1 CYCLIC OLEFIN RING-OPENED POLYMER, CYCLIC OLEFIN RING-OPENED POLYMER HYDRIDE, RESIN COMPOSITION, AND RESIN MOLDED BODY 日本ゼオン株式会社 2025-05-15 WO disclosed
WO-2025084431-A1 SURFACE TREATMENT AGENT, SURFACE TREATMENT AGENT KIT, SURFACE-MODIFIED MOLDED ARTICLE, AND METHOD FOR PRODUCING SURFACE-MODIFIED MOLDED ARTICLE 日本ゼオン株式会社 2025-04-24 WO disclosed
EP-4502076-A1 RESIN COMPOSITION, MOLDED BODY, AND OPTICAL MEMBER Zeon Corporation (JP) 2025-02-05 EP disclosed
WO-2024203650-A1 CELL CULTURING CONTAINER 日本ゼオン株式会社 2024-10-03 WO disclosed
WO-2024166915-A1 CELL CULTURE CONTAINER WITH SURFACE MODIFIER LAYER AND PRODUCTION METHOD THEREOF, AND METHOD FOR APPLYING SURFACE MODIFIER SOLUTION 日本ゼオン株式会社 2024-08-15 WO disclosed
US-20240199694-A1 OLIGOPEPTIDE ZEON CORPORATION (JP) 2024-06-20 US disclosed
WO-2024127881-A1 CYCLIC OLEFIN RING-OPENED POLYMER HYDRIDE, RESIN COMPOSITION AND FILM 日本ゼオン株式会社 2024-06-20 WO disclosed
US-6277923-B1 WITH VERY LOW CONTENT OF FOREIGN MATTERS, BY FILTERING WITH A ZETA POTENTIAL FILTER; MOLDINGS NIPPON ZEON CO., LTD (JP) 2001-08-21 US disclosed
EP-1026189-A1 THERMOPLASTIC DICYCLOPENTADIENE-BASE OPEN-RING POLYMERS, HYDROGENATED DERIVATIVES THEREOF, AND PROCESSES FOR THE PREPARATION OF BOTH Nippon Zeon Co., Ltd. (JP) 2000-08-09 EP disclosed
EP-1006134-A1 NORBORNENE POLYMER AND PROCESS FOR THE PREPARATION THEREOF NIPPON ZEON CO., LTD. (JP) 2000-06-07 EP disclosed
EP-0713893-B1 HYDROGENATED NORBORNENE-BASE RING-OPENING POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF NIPPON ZEON CO (JP) 1999-09-29 EP disclosed
EP-0936231-A1 MODIFIED THERMOPLASTIC NORBORNENE POLYMER AND PROCESS FOR THE PRODUCTION THEREOF NIPPON ZEON CO., LTD. (JP) 1999-08-18 EP disclosed
EP-0936230-A1 MODIFIED THERMOPLASTIC NORBORNENE POLYMER AND PROCESS FOR THE PRODUCTION THEREOF NIPPON ZEON CO., LTD. (JP) 1999-08-18 EP disclosed
EP-0930326-A1 NORBORNENE POLYMER AND PROCESS FOR PREPARING THE SAME NIPPON ZEON CO., LTD. (JP) 1999-07-21 EP disclosed
EP-0827975-A2 Cycloolefin-based polymer and process for producing the same NIPPON ZEON CO., LTD. (JP) 1998-03-11 EP disclosed
US-5681900-A Hydrogenated norbornene ring-opening polymerization product, a process for production thereof and uses thereof NIPPON ZEON CO., LTD. (JP) 1997-10-28 US disclosed
EP-0713893-A1 HYDROGENATED NORBORNENE-BASE RING-OPENING POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF NIPPON ZEON CO., LTD. (JP) 1996-05-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595359-B2 Resin composition for forming optical component, molded product, and optical component ASIC1, NLRP1, ASIC3 TRPM5 329/4885HTR2C 2692/4885HTR2A 2469/4885
US-12509489-B2 Oligopeptide FN1, HGF, TNFSF11 TRPM5 3943/4885HTR2C 2214/4885HTR2A 2138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.