Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7212339 | 0.73 | CHRNB2 (0.31) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL17386753 | 0.73 | MEN1 (0.33) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL17386755 | 0.69 | CHRNB2 (0.33) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4088340 | 0.68 | CHRNB2 (0.35) | ALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL28330060 | 0.68 | CHRNB2 (0.35) | ALDH1A1CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL3685419 | 0.68 | CHRNB2 (0.35) | ALDH1A1CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL4089006 | 0.68 | CHRNB2 (0.35) | ALDH1A1CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL5872685 | 0.68 | CHRNB2 (0.36) | CHRNB2CHRNA4 | |
| SCHEMBL17387267 | 0.68 | CHRNB2 (0.33) | KMT2AALDH1A1SMN1; SMN2CHRNB2CHRNA4 | |
| SCHEMBL17416153 | 0.68 | PTGS2 (0.33) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10005864-B2 | Metallocene compound, catalyst for olefin polymer, method for producing olefin polymer, and olefin polymer | JAPAN POLYETHYLENE CORPORATION (JP) | 2018-06-26 | — | — | US | disclosed |
| EP-3078670-B1 | METALLOCENE COMPOUND, CATALYST FOR OLEFIN POLYMER, METHOD FOR PRODUCING OLEFIN POLYMER, AND OLEFIN POLYMER | JAPAN POLYETHYLENE CORP (JP) | 2017-12-27 | — | — | EP | disclosed |
| US-20170320981-A1 | METALLOCENE COMPOUND, CATALYST FOR OLEFIN POLYMER, METHOD FOR PRODUCING OLEFIN POLYMER, AND OLEFIN POLYMER | JAPAN POLYETHYLENE CORPORATION (JP) | 2017-11-09 | — | — | US | disclosed |
| US-9783625-B2 | Metallocene compound, catalyst for olefin polymer, method for producing olefin polymer, and olefin polymer | JAPAN POLYETHYLENE CORPORATION (JP) | 2017-10-10 | — | — | US | disclosed |
| EP-2963045-B1 | METHOD FOR PRODUCING OLEFIN POLYMER WITH A METALLOCENE BASED CATALYST, AND OLEFIN POLYMER | JAPAN POLYETHYLENE CORP (JP) | 2016-12-21 | — | — | EP | disclosed |
| EP-3078670-A1 | METALLOCENE COMPOUND, CATALYST FOR OLEFIN POLYMER, METHOD FOR PRODUCING OLEFIN POLYMER, AND OLEFIN POLYMER | Japan Polyethylene Corporation (JP) | 2016-10-12 | — | — | EP | disclosed |
| US-20160009838-A1 | METALLOCENE COMPOUND, CATALYST FOR OLEFIN POLYMER, METHOD FOR PRODUCING OLEFIN POLYMER, AND OLEFIN POLYMER | JAPAN POLYETHYLENE CORPORATION (JP) | 2016-01-14 | — | — | US | disclosed |
| EP-2963045-A1 | METALLOCENE COMPOUND, CATALYST FOR OLEFIN POLYMER, METHOD FOR PRODUCING OLEFIN POLYMER, AND OLEFIN POLYMER | Japan Polyethylene Corporation (JP) | 2016-01-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170320981-A1 | METALLOCENE COMPOUND, CATALYST FOR OLEFIN POLYMER, METHOD FOR PRODUCING OLEFIN POLYMER, AND OLEFIN POLYMER | CPNE4, PIN4, PIN1 | ACHE 2279/4885MEN1 607/4885KMT2A 1568/4885 |
| US-20160009838-A1 | METALLOCENE COMPOUND, CATALYST FOR OLEFIN POLYMER, METHOD FOR PRODUCING OLEFIN POLYMER, AND OLEFIN POLYMER | CPNE4, ALOX12, PIN1 | ACHE 2373/4885MEN1 486/4885KMT2A 2334/4885 |
| US-10005864-B2 | Metallocene compound, catalyst for olefin polymer, method for producing olefin polymer, and olefin polymer | CPNE4, PPOX, PIN1 | ACHE 2885/4885MEN1 642/4885KMT2A 1328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.