Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.46 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.41 |
| ▸ | MC4R | P32245 | 2/20 | 0.40 |
| ▸ | MC5R | P33032 | 1/20 | 0.40 |
| ▸ | MC3R | P41968 | 1/20 | 0.40 |
| ▸ | RBP4 | P02753 | 2/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17530393 | 0.86 | CTSL (0.46) | ROCK2PRKG1FFAR1MC4RMC5R | |
| SCHEMBL17530361 | 0.83 | CTSB (0.55) | — | |
| SCHEMBL17530209 | 0.78 | CCR1 (0.47) | PARP10 | |
| SCHEMBL17530362 | 0.78 | NPC1 (0.46) | GAA | |
| SCHEMBL17529977 | 0.75 | CTSS (0.52) | ROCK2PRKG1 | |
| SCHEMBL17530396 | 0.74 | CTSL (0.48) | — | |
| SCHEMBL17530391 | 0.71 | CTSB (0.54) | — | |
| SCHEMBL17530211 | 0.69 | ROCK2 (0.56) | ROCK2PRKG1GAA | |
| SCHEMBL8098541 | 0.67 | FFAR1 (0.46) | FFAR1 | |
| SCHEMBL17530183 | 0.66 | CTSS (0.47) | MTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016027284-A2 | PIPERIDINE UREAS AS CATHEPSIN CYSTEINE PROTEASE INHIBITORS | ALKEM LABORATORIES LTD. (IN) | 2016-02-25 | — | — | WO | disclosed |