SCHEMBL1760841

SCHEMBL1760841

CCCCc1ccoc1C=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTRC Q99895 1/20 0.39
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
TYR P14679 1/20 0.34
HIF1A Q16665 1/20 0.34
EPAS1 Q99814 1/20 0.34
GAA P10253 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALDH1A1 P00352 3/20 0.33
ERAP1 Q9NZ08 1/20 0.33
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31
THRA P10827 1/20 0.31
THRB P10828 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31
SMN1; SMN2 Q16637 3/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2578095 0.95 HIF1A (0.40) CTRCCYP3A4TYRHIF1AEPAS1
SCHEMBL9534596 0.93 HIF1A (0.42) CYP3A4TYRHIF1AEPAS1TDP1
SCHEMBL7295420 0.89 ALDH1A1 (0.30) ALDH1A1
SCHEMBL574954 0.82
Water SCHEMBL2637003 0.80 ALDH1A1 (0.32) ALDH1A1
Butyl Alcohol SCHEMBL27800136 0.80 ALDH1A1 (0.35) GAATDP1L3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL7471068 0.79 CA2 (0.33) CA2
SCHEMBL136808 0.78 TSHR (0.38) CYP3A4CYP2D6CYP2C9GAATDP1
SCHEMBL9303455 0.78 HRH4 (0.44) CYP2D6ALDH1A1SMN1; SMN2LMNA
SCHEMBL11788637 0.77 PAOX (0.34) ALDH1A1HPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260022104-A1 AMINO COMPOUND AND METHOD FOR PRODUCING SAME, EPOXY RESIN CURING AGENT, AND EPOXY RESIN COMPOSITION AND CURED PRODUCT OF SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2026-01-22 US disclosed
US-20260008901-A1 AMINO COMPOSITION AND METHOD FOR PRODUCING SAME, EPOXY RESIN CURING AGENT, AND EPOXY RESIN COMPOSITION AND CURED PRODUCT OF SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2026-01-08 US disclosed
EP-4592281-A1 AMINO COMPOUND AND METHOD FOR PRODUCING SAME, EPOXY RESIN CURING AGENT, AND EPOXY RESIN COMPOSITION AND CURED PRODUCT OF SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-07-30 EP disclosed
EP-4592280-A1 AMINO COMPOSITION AND METHOD FOR PRODUCING SAME, EPOXY RESIN CURING AGENT, AND EPOXY RESIN COMPOSITION AND CURED PRODUCT OF SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-07-30 EP disclosed
EP-1697354-B1 ISOTHIAZOLE DIOXIDES AS CXC- AND CC- CHEMOKINE RECEPTOR LIGANDS MERCK SHARP & DOHME (US) 2013-08-07 EP disclosed
EP-1485089-B1 COMBINATION TREATMENTS FOR CHEMOKINE-MEDIATED DISEASES MERCK SHARP & DOHME (US) 2013-04-17 EP disclosed
EP-1539678-B1 3,4-DI-SUBSTITUTED CYCLOBUTENE-1, 2-DIONES AS CXC-CHEMOKINE RECEPTOR LIGANDS MERCK SHARP & DOHME (US) 2012-09-05 EP disclosed
US-20110213029-A1 3,4-Di-Substituted Cyclobutene-1,2-Diones as CXC-Chemokine Receptor Ligands SCHERING CORPORATION (US) 2011-09-01 US disclosed
US-7964646-B2 3,4-DI-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands SCHERING CORPORATION (US) 2011-06-21 US disclosed
US-7960433-B2 Treatment of chemokine mediated diseases SCHERING CORPORATION (US) 2011-06-14 US disclosed
EP-1539678-A1 3,4-DI-SUBSTITUTED CYCLOBUTENE-1, 2-DIONES AS CXC-CHEMOKINE RECEPTOR LIGANDS SCHERING CORPORATION (US) 2005-06-15 EP disclosed
EP-1485089-A1 COMBINATION TREATMENTS FOR CHEMOKINE-MEDIATED DISEASES SCHERING CORPORATION (US) 2004-12-15 EP disclosed
US-20040186142-A1 Thiadiazoledioxides and thiadiazoleoxides as CXC- and CC- chemokine receptor ligands SCHERING CORPORATION PHARMACOPEIA, INC. 2004-09-23 US disclosed
US-20040147559-A1 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands SCHERING CORPORATION AND PHARMACOPEIA, INC. 2004-07-29 US disclosed
US-20040106794-A1 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands SCHERING CORPORATION 2004-06-03 US disclosed
US-20040097547-A1 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands PHARMACOPEIA DRUG DISCOVERY 2004-05-20 US disclosed
WO-2004033440-A1 THIADIAZOLEDIOXIDES AND THIADIAZOLEOXIDES AS CXC- AND CC-CHEMOKINE RECEPTOR LIGANDS SCHERING CORPORATION (US) 2004-04-22 WO disclosed
US-20040053953-A1 Treatment of chemokine mediated diseases SCHERING CORPORATION 2004-03-18 US disclosed
WO-2004011418-A1 3,4-DI-SUBSTITUTED CYCLOBUTENE-1, 2-DIONES AS CXC-CHEMOKINE RECEPTOR LIGANDS SCHERING CORPORATION (US) 2004-02-05 WO disclosed
WO-2003080053-A1 COMBINATION TREATMENTS FOR CHEMOKINE-MEDIATED DISEASES SCHERING CORPORATION (US) 2003-10-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110213029-A1 3,4-Di-Substituted Cyclobutene-1,2-Diones as CXC-Chemokine Receptor Ligands CCR1, ACKR3, CXCR1 CTRC 1021/4885CYP3A4 3029/4885CYP2D6 1654/4885
US-20040147559-A1 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands CCR1, CXCR1, ACKR3 CTRC 1206/4885CYP3A4 2887/4885CYP2D6 1490/4885
US-20040186142-A1 Thiadiazoledioxides and thiadiazoleoxides as CXC- and CC- chemokine receptor ligands CXCR1, CCR2, CX3CR1 CTRC 721/4885CYP3A4 1187/4885CYP2D6 631/4885
US-20040053953-A1 Treatment of chemokine mediated diseases CCR1, CXCR3, CCL11 CTRC 1215/4885CYP3A4 2524/4885CYP2D6 1287/4885
US-20040097547-A1 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands CCR1, CXCR1, ACKR3 CTRC 1206/4885CYP3A4 2887/4885CYP2D6 1490/4885
US-20040106794-A1 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands CCR1, CXCR1, ACKR3 CTRC 1206/4885CYP3A4 2887/4885CYP2D6 1490/4885
US-20260022104-A1 AMINO COMPOUND AND METHOD FOR PRODUCING SAME, EPOXY RESIN CURING AGENT, AND EPOXY RESIN COMPOSITION AND CURED PRODUCT OF SAME ASH2L, PRMT1, RER1 CTRC 1313/4885CYP3A4 2988/4885CYP2D6 3508/4885
US-20260008901-A1 AMINO COMPOSITION AND METHOD FOR PRODUCING SAME, EPOXY RESIN CURING AGENT, AND EPOXY RESIN COMPOSITION AND CURED PRODUCT OF SAME PRMT1, SRM, BCAT2 CTRC 2801/4885CYP3A4 3386/4885CYP2D6 3967/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.