Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.61 |
| ▸ | THRA | P10827 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | SCD | O00767 | 1/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.51 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 5/20 | 0.50 |
| ▸ | PPARD | Q03181 | 5/20 | 0.50 |
| ▸ | PPARA | Q07869 | 5/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL288982 | 0.89 | PPARA (0.60) | ALDH1A1PPARGPPARAHDAC11FFAR1 | |
| SCHEMBL6285855 | 0.88 | ALDH1A1 (0.72) | ALDH1A1S1PR1S1PR3S1PR2FFAR1 | |
| SCHEMBL20854085 | 0.86 | ALDH1A1 (0.70) | ALDH1A1PTGS2CYP3A4S1PR1S1PR3 | |
| SCHEMBL6286434 | 0.86 | ALDH1A1 (0.70) | ALDH1A1PTGS2CYP3A4S1PR1S1PR3 | |
| SCHEMBL6288014 | 0.86 | ALDH1A1 (0.70) | ALDH1A1PTGS2CYP3A4S1PR1S1PR3 | |
| SCHEMBL10435207 | 0.86 | ALDH1A1 (0.70) | ALDH1A1PTGS2CYP3A4S1PR1S1PR3 | |
| SCHEMBL2185948 | 0.86 | ALDH1A1 (0.70) | ALDH1A1PTGS2CYP3A4S1PR1S1PR3 | |
| SCHEMBL17678269 | 0.85 | GPR84 (0.62) | GPR84THRATHRBALDH1A1PTGS2 | |
| SCHEMBL19166907 | 0.84 | GPR84 (0.61) | GPR84THRATHRBALDH1A1PTGS2 | |
| SCHEMBL16050416 | 0.84 | GPR84 (0.72) | GPR84THRATHRBALDH1A1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11185521-B2 | Substituted aromatic compounds and pharmaceutical compositions for the prevention and treatment of osteoporosis | Liminal Biosciences Limited (GB) | 2021-11-30 | — | — | US | disclosed |
| US-20210085626-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR TISSUE SELF-REPAIR AND REGENERATION | LIMINAL BIOSCIENCES LTD (GB) | 2021-03-25 | — | — | US | disclosed |
| EP-3203998-B1 | SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DIABETES | LIMINAL BIOSCIENCES LTD (GB) | 2021-03-10 | — | — | EP | disclosed |
| US-10869849-B2 | Substituted aromatic compounds and pharmaceutical compositions for tissue self-repair and regeneration | Liminal Biosciences Limited (GB) | 2020-12-22 | — | — | US | disclosed |
| US-20200237693-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF OSTEOPOROSIS | LIMINAL BIOSCIENCES INC (GB) | 2020-07-30 | — | — | US | disclosed |
| US-10391073-B2 | Substituted aromatic compounds and pharmaceutical compositions for tissue self-repair and regeneration | PROMETIC PHARMA SMT LIMITED (GB) | 2019-08-27 | — | — | US | disclosed |
| US-20170312237-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR TISSUE SELF-REPAIR AND REGENERATION | Liminal Biosciences Limited (GB) | 2017-11-02 | — | — | US | disclosed |
| US-20170312237-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR TISSUE SELF-REPAIR AND REGENERATION | Liminal Biosciences Limited (GB) | 2017-11-02 | — | — | US | disclosed |
| US-20170209399-A1 | Substituted Aromatic Compounds and Pharmaceutical Compositions For The Prevention And Treatment Of Diabetes | PROMETIC PHARMA SMT LIMITED (GB) | 2017-07-27 | — | — | US | disclosed |
| US-20170209399-A1 | Substituted Aromatic Compounds and Pharmaceutical Compositions For The Prevention And Treatment Of Diabetes | PROMETIC PHARMA SMT LIMITED (GB) | 2017-07-27 | — | — | US | disclosed |
| WO-2016074068-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR TISSUE SELF-REPAIR AND REGENERATION | PROMETIC BIOSCIENCES INC. (CA) | 2016-05-19 | — | — | WO | disclosed |
| WO-2016054728-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF OSTEOPOROSIS | PROMETIC BIOSCIENCES INC. (CA) | 2016-04-14 | — | — | WO | disclosed |
| WO-2016054726-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DIABETES | PROMETIC BIOSCIENCES INC. (CA) | 2016-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210085626-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR TISSUE SELF-REPAIR AND REGENERATION | COL1A1, CCNH, COL2A1 | GPR84 1983/4885THRA 2231/4885THRB 1461/4885 |
| US-20170312237-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR TISSUE SELF-REPAIR AND REGENERATION | CCNH, COL1A1, COL2A1 | GPR84 2125/4885THRA 2415/4885THRB 1698/4885 |
| US-20200237693-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF OSTEOPOROSIS | ADIPOR1, ADIPOR2, FN1 | GPR84 632/4885THRA 308/4885THRB 330/4885 |
| US-10391073-B2 | Substituted aromatic compounds and pharmaceutical compositions for tissue self-repair and regeneration | CCNH, COL1A1, COL2A1 | GPR84 2125/4885THRA 2415/4885THRB 1698/4885 |
| US-10869849-B2 | Substituted aromatic compounds and pharmaceutical compositions for tissue self-repair and regeneration | COL1A1, CCNH, COL2A1 | GPR84 1983/4885THRA 2231/4885THRB 1461/4885 |
| US-20170209399-A1 | Substituted Aromatic Compounds and Pharmaceutical Compositions For The Prevention And Treatment Of Diabetes | GPR119, LIPC, INSR | GPR84 1382/4885THRA 420/4885THRB 271/4885 |
| US-11185521-B2 | Substituted aromatic compounds and pharmaceutical compositions for the prevention and treatment of osteoporosis | ADIPOR1, ADIPOR2, FN1 | GPR84 632/4885THRA 308/4885THRB 330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.