Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.54 |
| ▸ | MMP9 | P14780 | 2/20 | 0.54 |
| ▸ | MMP8 | P22894 | 2/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.54 |
| ▸ | MMP3 | P08254 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.50 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8909236 | 0.87 | CYP1A2 (0.63) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL7327841 | 0.87 | CYP1A2 (0.63) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL7349315 | 0.87 | CYP1A2 (0.63) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL7988020 | 0.86 | MMP1 (0.53) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL1377052 | 0.86 | CPA3 (0.56) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL19506062 | 0.83 | MMP13 (0.46) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL6378071 | 0.82 | ALDH1A1 (0.53) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL7360995 | 0.82 | NPC1 (0.53) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL7075141 | 0.82 | MMP2 (0.80) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL7492579 | 0.82 | HSD11B1 (0.49) | MMP2MMP9MMP8MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3218009-B1 | PROCESS FOR THE CONJUGATION OF A PEPTIDE OR PROTEIN WITH A REAGENT COMPRISING A LEAVING GROUP INCLUDING A PORTION OF PEG | POLYTHERICS LTD (GB) | 2021-04-07 | — | — | EP | disclosed |
| US-10835616-B2 | Process for the conjugation of a peptide or protein with a reagent comprising a leaving group including a portion of PEG | POLYTHERICS LIMITED (GB) | 2020-11-17 | — | — | US | disclosed |
| US-20170304461-A1 | Process For The Conjugation Of A Peptide Or Protein With A Reagent Comprising A Leaving Group Including A Portion Of PEG | POLYTHERICS LIMITED (GB) | 2017-10-26 | — | — | US | disclosed |
| WO-2016059377-A1 | PROCESS FOR THE CONJUGATION OF A PEPTIDE OR PROTEIN WITH A REAGENT COMPRISING A LEAVING GROUP INCLUDING A PORTION OF PEG | POLYTHERICS LIMITED (GB) | 2016-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170304461-A1 | Process For The Conjugation Of A Peptide Or Protein With A Reagent Comprising A Leaving Group Including A Portion Of PEG | LNPEP, ANPEP, NGLY1 | MMP2 1524/4885MMP9 3447/4885MMP8 1386/4885 |
| US-10835616-B2 | Process for the conjugation of a peptide or protein with a reagent comprising a leaving group including a portion of PEG | LNPEP, ANPEP, NGLY1 | MMP2 1524/4885MMP9 3447/4885MMP8 1386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.