Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21863405 | 0.74 | ALDH1A1 (0.46) | ALDH1A1TSHRSMN1; SMN2HPGDLMNA | |
| SCHEMBL3594103 | 0.73 | P2RX7 (0.59) | ALDH1A1TSHRSMN1; SMN2HPGDLMNA | |
| SCHEMBL19303203 | 0.71 | ADK (0.41) | ALDH1A1TSHRSMN1; SMN2HPGDLMNA | |
| SCHEMBL11952909 | 0.70 | ALDH1A1 (0.41) | ALDH1A1TSHRSMN1; SMN2HPGDLMNA | |
| SCHEMBL10588731 | 0.67 | CETP (0.49) | ALDH1A1TSHRSMN1; SMN2HPGDLMNA | |
| SCHEMBL27612871 | 0.65 | GAA (0.50) | ALDH1A1SMN1; SMN2HPGDLMNAKMT2A | |
| SCHEMBL11316957 | 0.64 | POLB (0.50) | ALDH1A1TSHRSMN1; SMN2LMNAKMT2A | |
| SCHEMBL533863 | 0.64 | POLB (0.41) | ALDH1A1TSHRSMN1; SMN2HPGDLMNA | |
| SCHEMBL19086854 | 0.64 | POLB (0.41) | ALDH1A1TSHRSMN1; SMN2HPGDLMNA | |
| SCHEMBL20280414 | 0.64 | ALDH1A1 (0.43) | ALDH1A1TSHRSMN1; SMN2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11331314-B2 | Amine substituted triazole derivatives and uses thereof | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2022-05-17 | — | — | US | disclosed |
| US-11230540-B2 | Substituted triazole derivatives and uses thereof | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2022-01-25 | — | — | US | disclosed |
| US-11173151-B2 | Substituted triazole derivatives and uses thereof | BAYER AKTIENGESELLSCHAFT (DE) | 2021-11-16 | — | — | US | disclosed |
| EP-3700913-B1 | PRODRUGS OF SUBSTITUTED TRIAZOLE DERIVATIVES AND USES THEREOF | BAYER AG (DE) | 2021-11-10 | — | — | EP | disclosed |
| US-11149023-B2 | Substituted triazole derivatives and uses thereof | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-10-19 | — | — | US | disclosed |
| US-20210253557-A1 | SUBSTITUTED TRIAZOLE DERIVATIVES AND USES THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-08-19 | — | — | US | disclosed |
| US-11091463-B2 | Amide-substituted pyridinyltriazole derivatives and uses thereof | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-08-17 | — | — | US | disclosed |
| CN-113121504-A | Amide-substituted pyridyl triazole derivatives and use thereof | 拜耳制药股份公司 | 2021-07-16 | — | — | CN | disclosed |
| CN-113105403-A | Process for preparing 5-hydroxyalkyl-substituted 1-phenyl-1, 2, 4-triazole derivatives | 拜耳制药股份公司 | 2021-07-13 | — | — | CN | disclosed |
| CN-113105403-A | Process for preparing 5-hydroxyalkyl-substituted 1-phenyl-1, 2, 4-triazole derivatives | 拜耳制药股份公司 | 2021-07-13 | — | — | CN | disclosed |
| US-20170313665-A1 | HYDROXYALKYL-SUBSTITUTED PHENYLTRIAZOLE DERIVATIVES AND USES THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-11-02 | — | — | US | disclosed |
| US-9771352-B2 | Hydroxyalkyl-substituted phenyltriazole derivatives and uses thereof | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-26 | — | — | US | disclosed |
| US-9771352-B2 | Hydroxyalkyl-substituted phenyltriazole derivatives and uses thereof | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-26 | — | — | US | disclosed |
| EP-3215498-A1 | HYDROXYALKYL-SUBSTITUTED PHENYLTRIAZOLE DERIVATIVES AND USES THEREOF | Bayer Pharma Aktiengesellschaft (DE) | 2017-09-13 | — | — | EP | disclosed |
| EP-3215498-A1 | HYDROXYALKYL-SUBSTITUTED PHENYLTRIAZOLE DERIVATIVES AND USES THEREOF | Bayer Pharma Aktiengesellschaft (DE) | 2017-09-13 | — | — | EP | disclosed |
| CN-107074783-A | Hydroxyalkyl substituted phenyl triazole derivatives and uses thereof | 拜耳制药股份公司 | 2017-08-18 | — | — | CN | disclosed |
| WO-2016071212-A1 | HYDROXYALKYL-SUBSTITUTED PHENYLTRIAZOLE DERIVATIVES AND USES THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-05-12 | — | — | WO | disclosed |
| WO-2016071212-A1 | HYDROXYALKYL-SUBSTITUTED PHENYLTRIAZOLE DERIVATIVES AND USES THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-05-12 | — | — | WO | disclosed |
| US-20160122325-A1 | Hydroxyalkyl-substituted phenyltriazole derivatives and uses thereof | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-05-05 | — | — | US | disclosed |
| US-20160122325-A1 | Hydroxyalkyl-substituted phenyltriazole derivatives and uses thereof | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11331314-B2 | Amine substituted triazole derivatives and uses thereof | GLS, TNNI3, NAT1 | ALDH1A1 899/4885TSHR 1391/4885SMN1; SMN2 4299/4885 |
| US-11230540-B2 | Substituted triazole derivatives and uses thereof | GLS, TNNI3, CYP11B2 | ALDH1A1 858/4885TSHR 2036/4885SMN1; SMN2 4627/4885 |
| US-20210253557-A1 | SUBSTITUTED TRIAZOLE DERIVATIVES AND USES THEREOF | GLS, TNNI3, CYP11B2 | ALDH1A1 858/4885TSHR 2036/4885SMN1; SMN2 4627/4885 |
| US-20160122325-A1 | Hydroxyalkyl-substituted phenyltriazole derivatives and uses thereof | AADAC, HHAT, NAT1 | ALDH1A1 555/4885TSHR 2319/4885SMN1; SMN2 4804/4885 |
| US-20170313665-A1 | HYDROXYALKYL-SUBSTITUTED PHENYLTRIAZOLE DERIVATIVES AND USES THEREOF | AADAC, HHAT, NAT1 | ALDH1A1 555/4885TSHR 2319/4885SMN1; SMN2 4804/4885 |
| US-11149023-B2 | Substituted triazole derivatives and uses thereof | GLS, TNNI3, CYP11B2 | ALDH1A1 858/4885TSHR 2036/4885SMN1; SMN2 4627/4885 |
| US-11173151-B2 | Substituted triazole derivatives and uses thereof | GLS, TNNI3, CYP11B2 | ALDH1A1 858/4885TSHR 2036/4885SMN1; SMN2 4627/4885 |
| US-11091463-B2 | Amide-substituted pyridinyltriazole derivatives and uses thereof | AADAC, GLS, PDXK | ALDH1A1 1295/4885TSHR 1348/4885SMN1; SMN2 3828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.