Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.67 |
| ▸ | MEP1B | Q16820 | 7/20 | 0.64 |
| ▸ | MMP1 | P03956 | 5/20 | 0.64 |
| ▸ | MMP2 | P08253 | 4/20 | 0.64 |
| ▸ | MMP13 | P45452 | 4/20 | 0.64 |
| ▸ | MMP14 | P50281 | 4/20 | 0.64 |
| ▸ | MMP9 | P14780 | 2/20 | 0.64 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.64 |
| ▸ | MMP3 | P08254 | 1/20 | 0.64 |
| ▸ | MMP7 | P09237 | 1/20 | 0.64 |
| ▸ | MMP8 | P22894 | 1/20 | 0.64 |
| ▸ | MMP12 | P39900 | 1/20 | 0.64 |
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.63 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.63 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6438335 | 0.84 | ALDH1A1 (0.69) | CTSSMMP1MMP12KAT6APKM | |
| SCHEMBL6848743 | 0.83 | KAT6A (0.63) | CTSSKAT6APKMALDH1A1TPSAB1 | |
| SCHEMBL8318684 | 0.83 | CTSS (0.65) | CTSSKAT6APKMALDH1A1TPSAB1 | |
| SCHEMBL8954769 | 0.83 | KAT6A (0.63) | CTSSKAT6APKMALDH1A1TPSAB1 | |
| Hydrochloric Acid SCHEMBL27487670 | 0.82 | KAT6A (0.61) | CTSSKAT6APKMALDH1A1TPSAB1 | |
| Hydrochloric Acid SCHEMBL6791749 | 0.81 | TPSAB1 (0.70) | CTSSKAT6APKMALDH1A1TPSAB1 | |
| SCHEMBL2553981 | 0.80 | MEP1B (0.81) | MEP1BMMP1MMP2MMP13MMP14 | |
| SCHEMBL14045828 | 0.79 | ALDH1A1 (0.59) | CTSSKAT6APKMALDH1A1TPSAB1 | |
| SCHEMBL6791372 | 0.79 | ALDH1A1 (0.77) | CTSSKAT6APKMALDH1A1TPSAB1 | |
| SCHEMBL4926629 | 0.78 | MEP1B (0.53) | CTSSMEP1BMMP1MMP2MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269282-A1 | Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof | GENMEDICA THERAPEUTICS SL (ES) | 2008-10-30 | — | — | US | claimed |
| US-8841291-B2 | Selective hydroxamic acid based MMP-12 and MMP-13 inhibitors | NOVARTIS AG (CH) | 2014-09-23 | — | — | US | disclosed |
| US-8841291-B2 | Selective hydroxamic acid based MMP-12 and MMP-13 inhibitors | NOVARTIS AG (CH) | 2014-09-23 | — | — | US | disclosed |
| US-20140031399-A1 | SELECTIVE HYDROXAMIC ACID BASED MMP-12 AND MMP-13 INHIBITORS | NOVARTIS AG (CH) | 2014-01-30 | — | — | US | disclosed |
| US-20140031399-A1 | SELECTIVE HYDROXAMIC ACID BASED MMP-12 AND MMP-13 INHIBITORS | NOVARTIS AG (CH) | 2014-01-30 | — | — | US | disclosed |
| CN-102143942-A | Selective hydroxamic acid based MMP-12 and MMP-13 inhibitors | NOVARTIS AG | 2011-08-03 | — | — | CN | disclosed |
| US-20110112076-A1 | SELECTIVE HYDROXAMIC ACID BASED MMP-12 AND MMP-13 INHIBITORS | NOVARTIS AG (CH) | 2011-05-12 | — | — | US | disclosed |
| US-20110112076-A1 | SELECTIVE HYDROXAMIC ACID BASED MMP-12 AND MMP-13 INHIBITORS | NOVARTIS AG (CH) | 2011-05-12 | — | — | US | disclosed |
| EP-2318361-A1 | SELECTIVE HYDROXAMIC ACID BASED MMP-12 AND MMP-13 INHIBITORS | Novartis AG (CH) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010007027-A1 | SELECTIVE HYDROXAMIC ACID BASED MMP-12 AND MMP-13 INHIBITORS | NOVARTIS AG (CH) | 2010-01-21 | — | — | WO | disclosed |
| WO-2010007027-A1 | SELECTIVE HYDROXAMIC ACID BASED MMP-12 AND MMP-13 INHIBITORS | NOVARTIS AG (CH) | 2010-01-21 | — | — | WO | disclosed |
| US-20080269282-A1 | Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof | GENMEDICA THERAPEUTICS SL (ES) | 2008-10-30 | — | — | US | disclosed |
| US-20070066646-A1 | Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof | GENMEDICA THERAPEUTICS SL (ES) | 2007-03-22 | — | — | US | disclosed |
| US-20070066646-A1 | Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof | GENMEDICA THERAPEUTICS SL (ES) | 2007-03-22 | — | — | US | disclosed |
| US-20070066646-A1 | Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof | GENMEDICA THERAPEUTICS SL (ES) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269282-A1 | Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof | AOC2, AOC3, AOC1 | CTSS 2464/4885MEP1B 3107/4885MMP1 387/4885 |
| US-20110112076-A1 | SELECTIVE HYDROXAMIC ACID BASED MMP-12 AND MMP-13 INHIBITORS | MMP13, MMP11, MMP14 | CTSS 122/4885MEP1B 1085/4885MMP1 16/4885 |
| US-20070066646-A1 | Compounds for Inhibiting Copper-Containing Amine Oxidases and Uses Thereof | AOC2, AOC3, AOC1 | CTSS 2571/4885MEP1B 3118/4885MMP1 510/4885 |
| US-20140031399-A1 | SELECTIVE HYDROXAMIC ACID BASED MMP-12 AND MMP-13 INHIBITORS | MMP13, MMP11, MMP14 | CTSS 121/4885MEP1B 1137/4885MMP1 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.