Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.72 |
| ▸ | EBP | Q15125 | 5/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.72 |
| ▸ | MAPT | P10636 | 5/20 | 0.72 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.72 |
| ▸ | MEN1 | O00255 | 4/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.72 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.72 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.72 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.72 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.72 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.72 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.72 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.72 |
| ▸ | DRD3 | P35462 | 3/20 | 0.72 |
| ▸ | HTR6 | P50406 | 3/20 | 0.72 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.72 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17790416 | 1.00 | ESR1 (0.72) | ESR1EBPKMT2AMAPTADORA3 | |
| SCHEMBL19506967 | 0.87 | ESR1 (0.67) | ESR1EBPKMT2AMAPTADORA3 | |
| SCHEMBL17470686 | 0.84 | CYP19A1 (0.69) | ESR1EBPKMT2AMAPTADORA3 | |
| SCHEMBL8613926 | 0.84 | ESR1 (0.63) | ESR1EBPKMT2AMAPTADORA3 | |
| SCHEMBL8639618 | 0.84 | ESR1 (0.63) | ESR1EBPKMT2AMAPTADORA3 | |
| SCHEMBL8639615 | 0.84 | ESR1 (0.63) | ESR1EBPKMT2AMAPTADORA3 | |
| SCHEMBL8639612 | 0.84 | ESR1 (0.63) | ESR1EBPKMT2AMAPTADORA3 | |
| SCHEMBL7964377 | 0.84 | ESR1 (0.64) | ESR1EBPKMT2AMAPTADORA3 | |
| SCHEMBL10407739 | 0.84 | ESR1 (1.00) | ESR1EBPKMT2AMAPTADORA3 | |
| Zuclomiphene SCHEMBL34894 | 0.84 | ESR1 (1.00) | ESR1EBPKMT2AMAPTADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112918-A1 | RNA DEGRADERS AND USES THEREOF | ARRAKIS THERAPEUTICS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |
| US-11661396-B2 | Crystalline forms of zuclomiphene citrate | APOTEX INC. (CA) | 2023-05-30 | — | — | US | disclosed |
| US-20170349533-A1 | STABLE SOLID FORMS OF ENCLOMIPHENE AND ENCLOMIPHENE CITRATE | F I S - FABBRICA ITALIANA SINTETICI S P A (IT) | 2017-12-07 | — | — | US | disclosed |
| US-9822063-B2 | Stable solid forms of enclomiphene and enclomiphene citrate | F.I.S.—FABBRICA ITALIANA SINTETICI S.P.A (IT) | 2017-11-21 | — | — | US | disclosed |
| US-20160347705-A1 | STABLE SOLID FORMS OF ENCLOMIPHENE AND ENCLOMIPHENE CITRATE | F.I.S.- FABBRICA ITALIANA SINTETICI S.P.A (IT) | 2016-12-01 | — | — | US | disclosed |
| US-9428442-B2 | Process for the preparation of Clomiphene | F.I.S.—Fabbrica Italiana Sintetici S.p.A. (IT) | 2016-08-30 | — | — | US | disclosed |
| US-20160152551-A1 | PROCESS FOR THE PREPARATION OF CLOMIPHENE | F.I.S.- FABBRICA ITALIANA SINTETICI S.P.A (IT) | 2016-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11661396-B2 | Crystalline forms of zuclomiphene citrate | CYP11A1, APOL1, APOB | ESR1 1538/4885EBP 288/4885KMT2A 3608/4885 |
| US-20160152551-A1 | PROCESS FOR THE PREPARATION OF CLOMIPHENE | CYP19A1, CYP11A1, SI | ESR1 918/4885EBP 2258/4885KMT2A 2471/4885 |
| US-20160347705-A1 | STABLE SOLID FORMS OF ENCLOMIPHENE AND ENCLOMIPHENE CITRATE | CS, ACLY, OAT | ESR1 895/4885EBP 3148/4885KMT2A 3745/4885 |
| US-20170349533-A1 | STABLE SOLID FORMS OF ENCLOMIPHENE AND ENCLOMIPHENE CITRATE | CS, ACLY, OAT | ESR1 895/4885EBP 3148/4885KMT2A 3745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.