Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.48 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.33 |
| ▸ | ABAT | P80404 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17817825 | 0.83 | LOXL2 (0.48) | LOXL2SNCAHRH3ASIC3ABAT | |
| SCHEMBL17049798 | 0.82 | GABRA1 (0.42) | LOXL2SNCAPDE3BPDE3AMAOB | |
| SCHEMBL27643775 | 0.82 | LOXL2 (0.40) | LOXL2SNCAPDE3BPDE3AGAA | |
| SCHEMBL28190683 | 0.79 | KDM4E (0.48) | LOXL2SNCAGAA | |
| SCHEMBL25447720 | 0.78 | MPO (0.42) | LOXL2SNCACYP2A6MAOBMAOA | |
| SCHEMBL13755158 | 0.78 | LOXL2 (0.47) | LOXL2HRH3PDE3BPDE3A | |
| SCHEMBL13778118 | 0.78 | NOS2 (0.42) | PNMTCYP2A6MAOBMAOA | |
| SCHEMBL15556367 | 0.78 | PDE3B (0.41) | LOXL2PDE3BPDE3ACYP2A6GAA | |
| SCHEMBL20489787 | 0.78 | LOXL2 (0.47) | LOXL2PNMTMAOBMAOACSNK2A1 | |
| SCHEMBL51299 | 0.78 | LOXL2 (0.47) | LOXL2PNMTMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3031803-B1 | BENZOGUANAMINE COMPOUND HAVING AMINOMETHYL GROUP OR SALT THEREOF, AND METHOD FOR MANUFACTURING SAME | MITSUBISHI GAS CHEMICAL CO (JP) | 2019-04-24 | — | — | EP | claimed |
| CN-110234630-B | Phenylimidazolines having aminomethyl groups Compound or salt thereof and process for producing the same | 三菱瓦斯化学株式会社 | 2023-02-03 | — | — | CN | disclosed |
| EP-3604286-B1 | PHENYL IMIDAZOLINE COMPOUND HAVING AMINOMETHYL GROUP OR SALT THEREOF, OR PHENYL TETRAHYDROPYRIMIDINE COMPOUND HAVING AMINOMETHYL GROUP OR SALT THEREOF, AND PRODUCTION METHOD OF SAID COMPOUNDS OR SALTS THEREOF | MITSUBISHI GAS CHEMICAL CO (JP) | 2022-01-19 | — | — | EP | disclosed |
| US-11198676-B2 | Phenyl imidazoline compound having aminomethyl group or salt thereof, or phenyl tetrahydropyrimidine compound having aminomethyl group or salt thereof, and production method for such compounds or salts thereof | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2021-12-14 | — | — | US | disclosed |
| US-20200339516-A1 | PHENYL IMIDAZOLINE COMPOUND HAVING AMINOMETHYL GROUP OR SALT THEREOF, OR PHENYL TETRAHYDROPYRIMIDINE COMPOUND HAVING AMINOMETHYL GROUP OR SALT THEREOF, AND PRODUCTION METHOD FOR SUCH COMPOUNDS OR SALTS THEREOF | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2020-10-29 | — | — | US | disclosed |
| US-10662142-B2 | Process for production of aromatic compounds comprising at least two amine functions | RHODIA OPERATIONS (FR) | 2020-05-26 | — | — | US | disclosed |
| EP-3604286-A1 | PHENYL IMIDAZOLINE COMPOUND HAVING AMINOMETHYL GROUP OR SALT THEREOF, OR PHENYL TETRAHYDROPYRIMIDINE COMPOUND HAVING AMINOMETHYL GROUP OR SALT THEREOF, AND PRODUCTION METHOD OF SAID COMPOUNDS OR SALTS THEREOF | Mitsubishi Gas Chemical Company, Inc. (JP) | 2020-02-05 | — | — | EP | disclosed |
| US-20190292128-A1 | PROCESS FOR PRODUCTION OF AROMATIC COMPOUNDS COMPRISING AT LEAST TWO AMINE FUNCTIONS | SPECIALTY OPERATIONS FRANCE (FR) | 2019-09-26 | — | — | US | disclosed |
| EP-3031803-B1 | BENZOGUANAMINE COMPOUND HAVING AMINOMETHYL GROUP OR SALT THEREOF, AND METHOD FOR MANUFACTURING SAME | MITSUBISHI GAS CHEMICAL CO (JP) | 2019-04-24 | — | — | EP | disclosed |
| US-9458116-B2 | Benzoguanamine compound having aminomethyl group, or salt thereof, and method for manufacturing the same | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2016-10-04 | — | — | US | disclosed |
| US-20160176827-A1 | BENZOGUANAMINE COMPOUND HAVING AMINOMETHYL GROUP, OR SALT THEREOF, AND METHOD FOR MANUFACTURING THE SAME | MITSUBHIS GAS CHEMICAL COMPANY, INC. (JP) | 2016-06-23 | — | — | US | disclosed |
| EP-3031803-A1 | BENZOGUANAMINE COMPOUND HAVING AMINOMETHYL GROUP OR SALT THEREOF, AND METHOD FOR MANUFACTURING SAME | Mitsubishi Gas Chemical Company, Inc. (JP) | 2016-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200339516-A1 | PHENYL IMIDAZOLINE COMPOUND HAVING AMINOMETHYL GROUP OR SALT THEREOF, OR PHENYL TETRAHYDROPYRIMIDINE COMPOUND HAVING AMINOMETHYL GROUP OR SALT THEREOF, AND PRODUCTION METHOD FOR SUCH COMPOUNDS OR SALTS THEREOF | JAK2, IL4I1, INMT | LOXL2 4761/4885SNCA 3896/4885HRH3 232/4885 |
| US-11198676-B2 | Phenyl imidazoline compound having aminomethyl group or salt thereof, or phenyl tetrahydropyrimidine compound having aminomethyl group or salt thereof, and production method for such compounds or salts thereof | JAK2, IL4I1, INMT | LOXL2 4761/4885SNCA 3896/4885HRH3 232/4885 |
| US-20160176827-A1 | BENZOGUANAMINE COMPOUND HAVING AMINOMETHYL GROUP, OR SALT THEREOF, AND METHOD FOR MANUFACTURING THE SAME | BCAT2, GNMT, BCAT1 | LOXL2 3127/4885SNCA 495/4885HRH3 137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.