SCHEMBL17827611

SCHEMBL17827611

Cc1cc(C)c(C(=O)P(=O)(CCC(=O)OCCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C)C(=O)c2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15637257 0.89 TDP1 (0.32) TDP1
SCHEMBL17827612 0.83 SMN1; SMN2 (0.34) TDP1
SCHEMBL17827610 0.80 ALDH1A1 (0.35) TDP1
SCHEMBL26784274 0.78 THRB (0.33)
SCHEMBL17191296 0.77 ADRA2A (0.46)
SCHEMBL17827614 0.76 CRHR1 (0.33) TDP1
SCHEMBL17192835 0.76 DNM1 (0.40) TDP1
Hydrochloric Acid SCHEMBL15638142 0.76 MAPT (0.47)
SCHEMBL15635791 0.75 ALDH1A1 (0.34) TDP1
SCHEMBL15636584 0.74 TSHR (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9771319-B2 Cross-linker for the preparation of a new family of single ion conduction polymers for electrochemical devices and such polymers BELENOS CLEAN POWER HOLDING AG (CH) 2017-09-26 US disclosed
US-20160168086-A1 NOVEL CROSS-LINKER FOR THE PREPARATION OF A NEW FAMILY OF SINGLE ION CONDUCTION POLYMERS FOR ELECTROCHEMICAL DEVICES AND SUCH POLYMERS BELENOS CLEAN POWER HOLDING AG (CH) 2016-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160168086-A1 NOVEL CROSS-LINKER FOR THE PREPARATION OF A NEW FAMILY OF SINGLE ION CONDUCTION POLYMERS FOR ELECTROCHEMICAL DEVICES AND SUCH POLYMERS PPOX, PFAS, LPO TDP1 1977/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.