SCHEMBL1787701

SCHEMBL1787701

C=C(CCC(F)=Cc1ccc(OC)cc1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.43
NPC1 O15118 1/20 0.43
THRB P10828 2/20 0.43
ATM Q13315 1/20 0.43
TUBB4A P04350 1/20 0.42
TUBB P07437 1/20 0.42
TUBA3C P0DPH7 1/20 0.42
TUBA1B P68363 1/20 0.42
TUBA4A P68366 1/20 0.42
TUBB4B P68371 1/20 0.42
TUBB3 Q13509 1/20 0.42
TUBB2A Q13885 1/20 0.42
TUBB8 Q3ZCM7 1/20 0.42
TUBA3E Q6PEY2 1/20 0.42
TUBA1A Q71U36 1/20 0.42
TUBA1C Q9BQE3 1/20 0.42
TUBB6 Q9BUF5 1/20 0.42
TUBB2B Q9BVA1 1/20 0.42
TUBB1 Q9H4B7 1/20 0.42
AKR1C3 P42330 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1790765 0.84 RAB9A (0.44) RAB9ANPC1THRBATMAKR1C3
SCHEMBL5965987 0.82 AKR1C3 (0.43) AKR1C3MAPTALDH1A1LMNACYP3A4
SCHEMBL1790768 0.75 THRB (0.51) RAB9ANPC1THRBATMGSK3B
SCHEMBL7074865 0.75 TUBB4A (0.57) THRBATMTUBB4ATUBBTUBA3C
SCHEMBL7074870 0.75 TUBB4A (0.57) THRBATMTUBB4ATUBBTUBA3C
SCHEMBL9715109 0.74 NPC1 (0.52) RAB9ANPC1ATMAKR1C3MAPT
SCHEMBL4630810 0.73 ALDH1A1 (0.53) RAB9ATUBB4ATUBBTUBA3CTUBA1B
SCHEMBL4630813 0.73 ALDH1A1 (0.53) RAB9ATUBB4ATUBBTUBA3CTUBA1B
SCHEMBL1354040 0.72 MAPT (0.45) RAB9ANPC1THRBATMAKR1C3
SCHEMBL1921185 0.72 F2RL1 (0.62) RAB9ANPC1ATMALDH1A1NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110123929-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, PRODUCTION METHOD FOR THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT FUJIFILM CORPORATION (JP) 2011-05-26 US disclosed
US-7041416-B2 Photosensitive resin composition, transfer material, image forming method, color filter and producing method thereof and photomask and producing method thereof FUJI PHOTO FILM CO., LTD. (JP) 2006-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123929-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, PRODUCTION METHOD FOR THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT PPOX, CRY2, HCCS RAB9A 4200/4885NPC1 4759/4885THRB 1303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.