Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 5/20 | 0.42 |
| ▸ | TOP1 | P11387 | 4/20 | 0.38 |
| ▸ | CYCS | P99999 | 3/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5011966 | 0.88 | TERT (0.46) | TERTTOP1CYCSENPP2 | |
| SCHEMBL2064907 | 0.88 | TERT (0.51) | TERTTOP1CYCSENPP2 | |
| SCHEMBL5013770 | 0.85 | TERT (0.44) | TERTTOP1CYCSENPP2 | |
| SCHEMBL30831251 | 0.85 | TERT (0.44) | TERTTOP1CYCSENPP2 | |
| SCHEMBL28670658 | 0.84 | STAT3 (0.51) | TERTTOP1CYCSENPP2STAT3 | |
| SCHEMBL28665111 | 0.83 | STAT3 (0.50) | TERTTOP1CYCSENPP2STAT3 | |
| SCHEMBL16604345 | 0.82 | STAT3 (0.49) | TERTTOP1CYCSENPP2STAT3 | |
| SCHEMBL16433683 | 0.81 | TERT (0.46) | TERTTOP1CYCSENPP2 | |
| SCHEMBL14657713 | 0.80 | TERT (0.42) | TERTTOP1CYCSENPP2STAT3 | |
| SCHEMBL5015256 | 0.80 | TERT (0.42) | TERTTOP1CYCSENPP2STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110207956-A1 | INTRAMOLECULAR C-H AMINATION WITH PHOSPHORYL AZIDES | NATIONAL SCIENCE FOUNDATION | 2011-08-25 | — | — | US | disclosed |
| US-20110207956-A1 | INTRAMOLECULAR C-H AMINATION WITH PHOSPHORYL AZIDES | NATIONAL SCIENCE FOUNDATION | 2011-08-25 | — | — | US | disclosed |
| US-20110112288-A1 | Metal Porphyrin Catalyzed Olefin Aziridination with Sulfonyl Azides | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-05-12 | — | — | US | disclosed |
| US-20100174104-A1 | COBALT-CATALYZED ASYMMETRIC CYCLOPROPANATION WITH DIAZOSULFONES | UNIVERSITY OF SOUTH FLORIDA | 2010-07-08 | — | — | US | disclosed |
| US-7417142-B2 | Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, INC. (US) | 2008-08-26 | — | — | US | disclosed |
| US-7417142-B2 | Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, INC. (US) | 2008-08-26 | — | — | US | disclosed |
| US-7417142-B2 | Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, INC. (US) | 2008-08-26 | — | — | US | disclosed |
| US-20060030718-A1 | Cobalt-based catalysts for the cyclization of alkenes | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2006-02-09 | — | — | US | disclosed |
| US-20050124596-A1 | Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060030718-A1 | Cobalt-based catalysts for the cyclization of alkenes | PPOX, HCCS, ICOSLG | TERT 645/4885TOP1 1268/4885CYCS 6/4885 |
| US-20110207956-A1 | INTRAMOLECULAR C-H AMINATION WITH PHOSPHORYL AZIDES | CYCS, CCNH, CBR3 | TERT 3383/4885TOP1 1505/4885CYCS 1/4885 |
| US-20100174104-A1 | COBALT-CATALYZED ASYMMETRIC CYCLOPROPANATION WITH DIAZOSULFONES | CYCS, TST, CBS | TERT 1829/4885TOP1 2811/4885CYCS 1/4885 |
| US-20110112288-A1 | Metal Porphyrin Catalyzed Olefin Aziridination with Sulfonyl Azides | PPOX, SOD1, AP1S1 | TERT 2692/4885TOP1 2510/4885CYCS 76/4885 |
| US-20050124596-A1 | Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same | PPOX, PPIF, HMBS | TERT 1385/4885TOP1 1564/4885CYCS 57/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.